CA2202649C - Procede et appareil pour verifier la distribution d'un liquide - Google Patents
Procede et appareil pour verifier la distribution d'un liquide Download PDFInfo
- Publication number
- CA2202649C CA2202649C CA 2202649 CA2202649A CA2202649C CA 2202649 C CA2202649 C CA 2202649C CA 2202649 CA2202649 CA 2202649 CA 2202649 A CA2202649 A CA 2202649A CA 2202649 C CA2202649 C CA 2202649C
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- dispense
- receiver
- source
- electromagnetic radiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 38
- 238000012795 verification Methods 0.000 title description 7
- 239000012530 fluid Substances 0.000 claims abstract description 201
- 230000005670 electromagnetic radiation Effects 0.000 claims abstract description 75
- 230000002123 temporal effect Effects 0.000 claims description 17
- 230000002411 adverse Effects 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 8
- 238000001514 detection method Methods 0.000 claims description 7
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 description 16
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000000203 mixture Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 241000725303 Human immunodeficiency virus Species 0.000 description 4
- 239000012472 biological sample Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000008054 signal transmission Effects 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000013024 troubleshooting Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F13/00—Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups
- G01F13/006—Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups measuring volume in function of time
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N2035/1025—Fluid level sensing
Landscapes
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Fluid Mechanics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
La présente invention concerne des appareils et de procédés pour vérifier la distribution d'un liquide par un ajutage de distribution. Selon un procédé, une trajectoire de rayonnement électromagnétique entre une source et un récepteur est obstruée avec le fluide distribué par l'ajutage de distribution. L'intensité du rayonnement électromagnétique reçue par le récepteur est mesurée. L'intensité mesurée est comparée à une intensité prédéterminée pour vérifier la distribution de liquide par l'ajutage de distribution. Un appareil permettant de vérifier la distribution d'un liquide comporte une source de rayonnement électromagnétique, et un récepteur de ce rayonnement électromagnétique émanant de la source prévue à cet effet, qui est en liaison fonctionnelle avec la source du rayonnement électromagnétique de telle manière que ce dernier est reçu par le récepteur. La trajectoire suivie par le rayonnement électromagnétique entre la source et le récepteur est décalée, d'une distance prédéterminée, par rapport à l'extrémité de sortie de liquide de l'ajutage de distribution, de sorte que la distribution de liquide avec une grosse goutte de liquide suspendue à l'extrémité de sortie de l'ajutage de distribution obstrue la trajectoire, laquelle n'est pas obstruée par une petite goutte de liquide.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/332,307 | 1994-10-31 | ||
| US08/332,307 US5559339A (en) | 1994-10-31 | 1994-10-31 | Method and apparatus for verifying dispense of a fluid from a dispense nozzle |
| PCT/US1995/013091 WO1996013726A1 (fr) | 1994-10-31 | 1995-10-06 | Procede et appareil pour verifier la distribution d'un liquide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2202649A1 CA2202649A1 (fr) | 1996-05-09 |
| CA2202649C true CA2202649C (fr) | 2000-12-19 |
Family
ID=29422761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2202649 Expired - Fee Related CA2202649C (fr) | 1994-10-31 | 1995-10-06 | Procede et appareil pour verifier la distribution d'un liquide |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2202649C (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852291B1 (en) | 2000-10-11 | 2005-02-08 | Innovadyne Technologies, Inc. | Hybrid valve apparatus and method for fluid handling |
| US7135146B2 (en) | 2000-10-11 | 2006-11-14 | Innovadyne Technologies, Inc. | Universal non-contact dispense peripheral apparatus and method for a primary liquid handling device |
| EP1470427B1 (fr) | 2002-01-25 | 2007-11-07 | Innovadyne Technologies, Inc. | Procede de distribution de faibles volumes de liquide sans contact |
-
1995
- 1995-10-06 CA CA 2202649 patent/CA2202649C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2202649A1 (fr) | 1996-05-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5559339A (en) | Method and apparatus for verifying dispense of a fluid from a dispense nozzle | |
| CN103026241B (zh) | 自动分析装置 | |
| US5670946A (en) | Smoke detector sensitivity testing apparatus | |
| US6372506B1 (en) | Apparatus and method for verifying drop delay in a flow cytometer | |
| EP1059535B1 (fr) | Procédé pour vérifier un volume aspiré de fluide dans un système diagnostique automatisé | |
| US6370942B1 (en) | Method for verifying the integrity of a fluid transfer | |
| US6060320A (en) | Method of verifying aspirated volume in automatic diagnostic system | |
| EP1316802B1 (fr) | Méthode d'analyse d'une reaction de la coagulation du sang | |
| US5834314A (en) | Method and apparatus for metering a fluid | |
| US4317520A (en) | Servo system to control the spatial position of droplet formation of a fluid jet in a cell sorting apparatus | |
| US9857388B2 (en) | Automatic analyzer | |
| US20090266149A1 (en) | Differentiating Between Abnormal Sample Viscosities and Pipette Clogging During Aspiration | |
| EP0753750A2 (fr) | Procédé et dispositif pour aspirer et remettre des échantillons liquides | |
| JP2010539510A (ja) | 臨床サンプリング・ピペットにおける詰まりの検出 | |
| JPH0217448A (ja) | 空気式検出方式 | |
| JP2002519704A (ja) | 吸引および分配システムをモニタするための方法および装置 | |
| EP0075440B1 (fr) | Procédé et système de mélange de réactifs | |
| CA2202649C (fr) | Procede et appareil pour verifier la distribution d'un liquide | |
| EP0042337B1 (fr) | Procédé et dispositif de distribution de doses de fluides biologiques | |
| JPH05223830A (ja) | 分注量検出装置および方法 | |
| WO1997011349A1 (fr) | Compteur optique de particules utilisant un calibreur de champ | |
| US6476911B1 (en) | Backscatter instrument for monitoring particulate levels in a gas stream | |
| JP2013044692A (ja) | 分注機構及びこれを用いた自動分析装置 | |
| CA2427164C (fr) | Methode de mesurage dynamique du volume d'ecoulement d'un fluide et appareil connexe | |
| EP0394041A2 (fr) | Dispositif d'écoulement capillaire et instrument de lecture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20151006 |