CA2206519A1 - Derives de dibenz¬cd,f|indole - Google Patents

Derives de dibenz¬cd,f|indole

Info

Publication number
CA2206519A1
CA2206519A1 CA002206519A CA2206519A CA2206519A1 CA 2206519 A1 CA2206519 A1 CA 2206519A1 CA 002206519 A CA002206519 A CA 002206519A CA 2206519 A CA2206519 A CA 2206519A CA 2206519 A1 CA2206519 A1 CA 2206519A1
Authority
CA
Canada
Prior art keywords
compound
addition salt
acid addition
dibenz
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002206519A
Other languages
English (en)
Inventor
Rudolf Karl Andreas Giger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2206519A1 publication Critical patent/CA2206519A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Des 1-alkyl-9,10-dihydroxy-4,5,5a,6-tétrahydro-dibenz[cd,f]indoles peuvent être utilisés dans le traitement de la maladie de Parkinson, l'abus d'alcool et la pharmacodépendance. Dans la formule, R¿1?, R¿2? et R¿3? représentent, indépendamment l'un de l'autre, alkyle en C¿1-4? sous forme libre ou de sel d'addition d'acide.
CA002206519A 1994-12-30 1995-12-29 Derives de dibenz¬cd,f|indole Abandoned CA2206519A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9426407.4 1994-12-30
GBGB9426407.4A GB9426407D0 (en) 1994-12-30 1994-12-30 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
CA2206519A1 true CA2206519A1 (fr) 1996-07-11

Family

ID=10766712

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002206519A Abandoned CA2206519A1 (fr) 1994-12-30 1995-12-29 Derives de dibenz¬cd,f|indole

Country Status (8)

Country Link
EP (1) EP0800515A1 (fr)
JP (1) JPH11504616A (fr)
AU (1) AU4435896A (fr)
CA (1) CA2206519A1 (fr)
GB (1) GB9426407D0 (fr)
IL (1) IL116606A0 (fr)
WO (1) WO1996020927A1 (fr)
ZA (1) ZA9511036B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030048026A (ko) 2001-07-06 2003-06-18 펜웨스트 파머슈티칼즈 컴파니 옥시모르폰의 서방형 제제
CN1610551A (zh) 2001-07-06 2005-04-27 恩德制药公司 用作止痛剂的6－羟基羟吗啡酮的肠胃外给药
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI70407C (fi) * 1978-06-23 1986-09-19 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4,5,5a,6-tetra-hydro-dibens/cd f/indol derivat
BE889324A (fr) * 1980-06-27 1981-12-22 Sandoz Sa Nouveaux derives du dibenz(cd,f)indole, leur preparation et leur application comme medicaments
CH660187A5 (en) * 1983-04-06 1987-03-31 Sandoz Ag Dibenz[cd,f]indole derivatives, their preparation and the pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU4435896A (en) 1996-07-24
IL116606A0 (en) 1996-03-31
EP0800515A1 (fr) 1997-10-15
GB9426407D0 (en) 1995-03-01
JPH11504616A (ja) 1999-04-27
WO1996020927A1 (fr) 1996-07-11
ZA9511036B (en) 1997-06-30

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Legal Events

Date Code Title Description
FZDE Discontinued