CA2210532C - Procede et structure d'emballage pour la conservation et le stockage cryogeniques d'equivalents de tissu de culture - Google Patents

Procede et structure d'emballage pour la conservation et le stockage cryogeniques d'equivalents de tissu de culture Download PDF

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Publication number
CA2210532C
CA2210532C CA002210532A CA2210532A CA2210532C CA 2210532 C CA2210532 C CA 2210532C CA 002210532 A CA002210532 A CA 002210532A CA 2210532 A CA2210532 A CA 2210532A CA 2210532 C CA2210532 C CA 2210532C
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CA
Canada
Prior art keywords
tray
tissue
lid
carrier
flange
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002210532A
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English (en)
Other versions
CA2210532A1 (fr
Inventor
Stephen R. Watson
Mehmet Toner
Alexander G. Tschumakow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organogenesis Inc
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/380,099 external-priority patent/US5891617A/en
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Publication of CA2210532A1 publication Critical patent/CA2210532A1/fr
Application granted granted Critical
Publication of CA2210532C publication Critical patent/CA2210532C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/16Physical preservation processes
    • A01N1/162Temperature processes, e.g. following predefined temperature changes over time
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D55/00Accessories for container closures not otherwise provided for
    • B65D55/02Locking devices; Means for discouraging or indicating unauthorised opening or removal of closure
    • B65D55/06Deformable or tearable wires, strings or strips; Use of seals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/10Container closures formed after filling
    • B65D77/20Container closures formed after filling by applying separate lids or covers, i.e. flexible membrane or foil-like covers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/50Containers, packaging elements or packages, specially adapted for particular articles or materials for living organisms, articles or materials sensitive to changes of environment or atmospheric conditions, e.g. land animals, birds, fish, water plants, non-aquatic plants, flower bulbs, cut flowers or foliage

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une nouvelle structure d'emballage de cryoconservation efficace de tissus mammaliens récoltés et d'équivalents de tissus de culture obtenus par la technique in vitro. Le procédé selon l'invention consiste à immerger un tissu mammalien ou un équivalent de tissu de culture dans une solution cryoprotectrice, à agiter la solution cryoprotectrice et le tissu immergé de sorte que la solution cryoprotectrice pénètre efficacement dans le tissu, et à congeler le tissu à une vitesse de congélation très faible. Dans la phase de congélation, la formation de glace extracellulaire est induite par ensemencement. Le tissu cryoconservé peut être stocké pendant des périodes indéfinies avant d'être utilisé. L'équivalent de tissu de culture est un modèle in vitro du tissu humain équivalent tel que la peau ou la cornée, qui, une fois retiré du stockage peut être utilisé pour une transplantation ou un implant in vivo ou pour le titrage de composés in vitro.
CA002210532A 1995-01-30 1996-01-30 Procede et structure d'emballage pour la conservation et le stockage cryogeniques d'equivalents de tissu de culture Expired - Fee Related CA2210532C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US380,099 1995-01-30
US08/380,099 US5891617A (en) 1993-09-15 1995-01-30 Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing
PCT/US1996/001217 WO1996024018A1 (fr) 1995-01-30 1996-01-30 Procede et structure d'emballage pour la conservation et le stockage cryogeniques d'equivalents de tissu de culture

Publications (2)

Publication Number Publication Date
CA2210532A1 CA2210532A1 (fr) 1996-08-08
CA2210532C true CA2210532C (fr) 2007-05-15

Family

ID=38069020

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002210532A Expired - Fee Related CA2210532C (fr) 1995-01-30 1996-01-30 Procede et structure d'emballage pour la conservation et le stockage cryogeniques d'equivalents de tissu de culture

Country Status (1)

Country Link
CA (1) CA2210532C (fr)

Also Published As

Publication number Publication date
CA2210532A1 (fr) 1996-08-08

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