CA2216912A1 - Recepteur hdgnr10 de chimiokine de la proteine g humaine - Google Patents

Recepteur hdgnr10 de chimiokine de la proteine g humaine Download PDF

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Publication number
CA2216912A1
CA2216912A1 CA002216912A CA2216912A CA2216912A1 CA 2216912 A1 CA2216912 A1 CA 2216912A1 CA 002216912 A CA002216912 A CA 002216912A CA 2216912 A CA2216912 A CA 2216912A CA 2216912 A1 CA2216912 A1 CA 2216912A1
Authority
CA
Canada
Prior art keywords
polypeptide
receptor
compound
dna
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002216912A
Other languages
English (en)
Inventor
Yi Li
Steven M. Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002562211A priority Critical patent/CA2562211A1/fr
Priority to CA002216912A priority patent/CA2216912A1/fr
Priority to CA002562162A priority patent/CA2562162A1/fr
Publication of CA2216912A1 publication Critical patent/CA2216912A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des polypeptides de chémokines récepteurs aux protéines G humaines et l'ADN (ARN) codant de tels polypeptides, ainsi qu'un procédé de production de ces polypeptides par des techniques de recombinaison. Elle concerne également des procédés d'utilisation desdits polypeptides pour l'identification d'antagonistes et d'agonistes à ces polypeptides, ainsi que des procédés d'utilisation thérapeutique des agonistes et des antagonistes dans le traitement, respectivement, de la sous-expression et de la surexpression des polypeptides de chémokines récepteurs de protéines G. L'invention a en outre pour objet des méthodes de diagnostic permettant de détecter une mutation dans les séquences d'acide nucléique des chémokines récepteurs de protéines G, de même qu'une concentration de la forme soluble des récepteurs dans un échantillon tiré d'un hôte.
CA002216912A 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de la proteine g humaine Abandoned CA2216912A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002562211A CA2562211A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine
CA002216912A CA2216912A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de la proteine g humaine
CA002562162A CA2562162A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002216912A CA2216912A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de la proteine g humaine

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CA002562162A Division CA2562162A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine
CA002562211A Division CA2562211A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine

Publications (1)

Publication Number Publication Date
CA2216912A1 true CA2216912A1 (fr) 1996-12-12

Family

ID=4161544

Family Applications (3)

Application Number Title Priority Date Filing Date
CA002562162A Abandoned CA2562162A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine
CA002216912A Abandoned CA2216912A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de la proteine g humaine
CA002562211A Abandoned CA2562211A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002562162A Abandoned CA2562162A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002562211A Abandoned CA2562211A1 (fr) 1995-06-06 1995-06-06 Recepteur hdgnr10 de chimiokine de proteine-g humaine

Country Status (1)

Country Link
CA (3) CA2562162A1 (fr)

Also Published As

Publication number Publication date
CA2562162A1 (fr) 1996-12-12
CA2562211A1 (fr) 1996-12-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued