CA2218281C - Procede et appareil de determination non invasive de l'hematocrite - Google Patents

Procede et appareil de determination non invasive de l'hematocrite Download PDF

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Publication number
CA2218281C
CA2218281C CA002218281A CA2218281A CA2218281C CA 2218281 C CA2218281 C CA 2218281C CA 002218281 A CA002218281 A CA 002218281A CA 2218281 A CA2218281 A CA 2218281A CA 2218281 C CA2218281 C CA 2218281C
Authority
CA
Canada
Prior art keywords
signals
blood
current
voltage
quadrature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002218281A
Other languages
English (en)
Other versions
CA2218281A1 (fr
Inventor
Paul W. Ruben
Allan L. Kaminsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microcor Inc
Original Assignee
Microcor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/425,404 external-priority patent/US5526808A/en
Priority claimed from US08/602,700 external-priority patent/US5642734A/en
Application filed by Microcor Inc filed Critical Microcor Inc
Publication of CA2218281A1 publication Critical patent/CA2218281A1/fr
Application granted granted Critical
Publication of CA2218281C publication Critical patent/CA2218281C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14535—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring haematocrit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
CA002218281A 1995-04-20 1996-04-03 Procede et appareil de determination non invasive de l'hematocrite Expired - Fee Related CA2218281C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US08/425,404 1995-04-20
US08/425,404 US5526808A (en) 1990-10-04 1995-04-20 Method and apparatus for noninvasively determining hematocrit
US48449095A 1995-06-07 1995-06-07
US08/484,490 1995-06-07
US08/602,700 US5642734A (en) 1990-10-04 1996-02-16 Method and apparatus for noninvasively determining hematocrit
US08/602,700 1996-02-16
PCT/US1996/004547 WO1996032883A1 (fr) 1995-04-20 1996-04-03 Procede et appareil de determination non invasive de l'hematocrite

Publications (2)

Publication Number Publication Date
CA2218281A1 CA2218281A1 (fr) 1996-10-24
CA2218281C true CA2218281C (fr) 2004-08-17

Family

ID=27411466

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002218281A Expired - Fee Related CA2218281C (fr) 1995-04-20 1996-04-03 Procede et appareil de determination non invasive de l'hematocrite

Country Status (6)

Country Link
EP (1) EP0955871A4 (fr)
JP (1) JP3844779B2 (fr)
CN (1) CN1244779A (fr)
AU (1) AU5383796A (fr)
CA (1) CA2218281C (fr)
WO (1) WO1996032883A1 (fr)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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US6766191B1 (en) 1990-10-04 2004-07-20 Microcor, Inc. System and method for in-vivo hematocrit measurement using impedance and pressure plethysmography
ES2143911B1 (es) * 1997-03-06 2000-12-01 Nte Sa Metodo y aparato para medir la concentracion y composicion de biomasa.
JP2002501802A (ja) * 1998-02-04 2002-01-22 ダーマル セラピー (バルバドス) インク. 体液中のグルコースを非侵襲的に測定するための方法及び装置
AU2001261847A1 (en) * 2000-05-16 2001-11-26 Microcor, Inc. System and method for in-vivo hematocrit measurement using impedance and pressure plethysmography
US7228170B2 (en) 2000-08-14 2007-06-05 Renal Research Institute, Llc Device and method for monitoring and controlling physiologic parameters of a dialysis patient using segmental bioimpedance
US6615077B1 (en) 2000-08-14 2003-09-02 Renal Research Institute, Llc Device and method for monitoring and controlling physiologic parameters of a dialysis patient using segmental bioimpedence
WO2004086940A2 (fr) 2003-03-25 2004-10-14 Fresenius Medical Care Holdings, Inc. Dispositif et procede permettant d'executer une tomographie a impedance electrique
US8414498B2 (en) 2003-05-12 2013-04-09 Cheetah Medical, Inc. System, method and apparatus for measuring blood flow and blood volume
EP1628564B1 (fr) * 2003-06-03 2014-02-12 Orsense Ltd. Procédé et système destinés à être utilisés dans des mesures optiques non invasives de paramètres sanguins
EP2579031B1 (fr) 2003-12-04 2017-09-27 Panasonic Healthcare Holdings Co., Ltd. Détecteur de mesure de composant sanguin et d'hématocrit
US8088271B2 (en) * 2003-12-04 2012-01-03 Panasonic Corporation Method of measuring hematocrit (Hct), sensor used in the method, and measuring device
JP4689601B2 (ja) 2004-04-19 2011-05-25 パナソニック株式会社 血液成分の測定方法、それに用いるバイオセンサおよび測定装置
US7356366B2 (en) * 2004-08-02 2008-04-08 Cardiac Pacemakers, Inc. Device for monitoring fluid status
AU2006215274B2 (en) 2005-02-15 2011-12-22 Cheetah Medical, Inc. System, method and apparatus for measuring blood flow and blood volume
JP4947440B2 (ja) * 2005-11-10 2012-06-06 バイオボーション・アーゲー 身体組織中のグルコース・レベルを割り出すための装置
JP4640608B2 (ja) * 2005-12-12 2011-03-02 ソニー株式会社 検出装置及び検出方法
JP5071768B2 (ja) * 2006-12-08 2012-11-14 学校法人日本大学 血流速度測定装置
JP5071767B2 (ja) * 2006-12-08 2012-11-14 学校法人日本大学 生体組織血流量測定装置
US9095271B2 (en) 2007-08-13 2015-08-04 Cheetah Medical, Inc. Dynamically variable filter
US8876725B2 (en) 2007-02-23 2014-11-04 Cheetah Medical, Inc. Method and system for estimating exercise capacity
US8764667B2 (en) 2007-03-07 2014-07-01 Cheetah Medical, Inc. Method and system for monitoring sleep
WO2008129535A1 (fr) 2007-04-19 2008-10-30 Cheetah Medical Ltd. Procédé, appareil et système destinés à prévoir une dissociation électrochimique
US8168063B2 (en) 2008-07-09 2012-05-01 Baxter International Inc. Dialysis system having filtering method for determining therapy prescriptions
US9514283B2 (en) 2008-07-09 2016-12-06 Baxter International Inc. Dialysis system having inventory management including online dextrose mixing
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US8062513B2 (en) 2008-07-09 2011-11-22 Baxter International Inc. Dialysis system and machine having therapy prescription recall
US7981281B2 (en) 2008-07-09 2011-07-19 Baxter International, Inc. Dialysis system having regimen generation methodology
DK2346395T3 (en) * 2008-09-22 2018-06-06 Cheetah Medical Inc SYSTEM AND PROCEDURE FOR DETERMINING BLOOD FLOW
RU2395086C1 (ru) * 2008-11-24 2010-07-20 Государственное образовательное учреждение высшего профессионального образования Самарский государственный аэрокосмический университет имени академика С.П. Королева Устройство для определения показателя гематокрита
JP5628289B2 (ja) 2009-04-17 2014-11-19 バイオボーション・アーゲーBiovotion AG グルコース決定のための広帯域フィールド応答特性測定
US8282829B2 (en) 2009-05-20 2012-10-09 Baxter International Inc. System and method for automated data collection of twenty-four hour ultrafiltration and other patient parameters using wired or wireless technology
US8926551B2 (en) 2009-07-07 2015-01-06 Baxter Healthcare Inc. Peritoneal dialysis therapy with large dialysis solution volumes
JP2011078443A (ja) * 2009-10-02 2011-04-21 Tanita Corp 生体測定装置
CN106073731B (zh) * 2011-02-17 2020-01-31 高通股份有限公司 用于确定哺乳动物心血管分量的方法和系统
CN102694509B (zh) * 2011-03-22 2017-02-15 北京汉朔科技有限公司 具有交流激励功能的集成电生理信号放大器
JP5726662B2 (ja) * 2011-07-22 2015-06-03 学校法人上智学院 血液インピーダンス計測装置、人工透析装置及び血液のインピーダンスを計測する装置の作動方法
BR112013028102A2 (pt) 2011-07-25 2017-06-27 Cheetah Medical Inc sistema e método para monitorar a hemodinâmica
US8623660B2 (en) * 2011-09-30 2014-01-07 Lifescan Scotland Limited Hand-held test meter with phase-shift-based hematocrit measurement circuit
CN103149132B (zh) * 2013-03-18 2015-02-25 深圳市理邦精密仪器股份有限公司 提高测量红细胞压积准确度的检测系统、及运行控制方法
US20150196224A1 (en) * 2014-01-16 2015-07-16 Dermal Therapy (Barbados) Inc. Implantable Sensor and Method for Such Sensor
WO2015178924A1 (fr) 2014-05-23 2015-11-26 Nova Biomedical Corporation Procédé et système de détection d'hémolyse
CN105403691B (zh) * 2016-01-01 2017-08-18 赛奥生物科技(青岛)有限公司 一种血液试剂分析系统
JP7034427B2 (ja) 2016-04-11 2022-03-14 センサム 病変部の検知された特性に基づいて治療法の推奨を行う医療装置
US11568990B2 (en) * 2016-11-21 2023-01-31 Sensome SAS Characterizing and identifying biological structure
AU2018300002B2 (en) 2017-07-11 2021-02-18 Fresenius Medical Care Holdings, Inc. Techniques for determining fluid volumes using bioimpedance information
JP6895876B2 (ja) * 2017-12-13 2021-06-30 アークレイ株式会社 血液中のヘマトクリット値を測定する測定方法および測定装置
WO2020232706A1 (fr) * 2019-05-23 2020-11-26 麦层移动健康管理有限公司 Procédé et dispositif de mesure de fluide corporel et de ses changements et de mesure de changements de débit sanguin
US12543980B2 (en) 2021-06-21 2026-02-10 Instrumentation Laboratory Company Determining a platelet aggregation value
CN118019492A (zh) * 2021-08-13 2024-05-10 医科大学克利夫兰医药中心 内源性s-亚硝基硫醇的非侵入性测量

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994284A (en) * 1975-12-31 1976-11-30 Systron Donner Corporation Flow rate computer adjunct for use with an impedance plethysmograph and method
US4425920A (en) * 1980-10-24 1984-01-17 Purdue Research Foundation Apparatus and method for measurement and control of blood pressure
DE3202067C2 (de) * 1982-01-23 1984-06-20 Holger Dr. 5100 Aachen Kiesewetter Vorrichtung zur Bestimmung des Hämatokritwertes
SE455043B (sv) * 1982-04-22 1988-06-20 Karolinska Inst Anordning for overvakning av menniskokroppens vetskebalans genom metning av kroppens impedans
JP2665806B2 (ja) * 1989-09-13 1997-10-22 株式会社豊田中央研究所 ヘマトクリット測定装置
US5404879A (en) * 1993-01-19 1995-04-11 Hewlett-Packard Method and apparatus for automatic non-invasive monitoring of a patient's blood pressure
JP3345481B2 (ja) * 1993-09-22 2002-11-18 興和株式会社 脈波分光計

Also Published As

Publication number Publication date
JP3844779B2 (ja) 2006-11-15
CN1244779A (zh) 2000-02-16
JP2001500392A (ja) 2001-01-16
CA2218281A1 (fr) 1996-10-24
WO1996032883A1 (fr) 1996-10-24
EP0955871A4 (fr) 2000-03-22
AU5383796A (en) 1996-11-07
EP0955871A1 (fr) 1999-11-17

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Effective date: 20130403