CA2222613C - A device for delivering a preselected molecule into systemic circulation - Google Patents

A device for delivering a preselected molecule into systemic circulation Download PDF

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Publication number
CA2222613C
CA2222613C CA002222613A CA2222613A CA2222613C CA 2222613 C CA2222613 C CA 2222613C CA 002222613 A CA002222613 A CA 002222613A CA 2222613 A CA2222613 A CA 2222613A CA 2222613 C CA2222613 C CA 2222613C
Authority
CA
Canada
Prior art keywords
cells
blood
capsule
vessel
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002222613A
Other languages
English (en)
French (fr)
Other versions
CA2222613A1 (en
Inventor
H. David Humes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RENAMED BIOLOGICS Inc
Original Assignee
Nephros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nephros Therapeutics Inc filed Critical Nephros Therapeutics Inc
Publication of CA2222613A1 publication Critical patent/CA2222613A1/en
Application granted granted Critical
Publication of CA2222613C publication Critical patent/CA2222613C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/0105—Open ended, i.e. legs gathered only at one side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/005—Rosette-shaped, e.g. star-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0067—Three-dimensional shapes conical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Threshing Machine Elements (AREA)
  • Electrotherapy Devices (AREA)
CA002222613A 1995-06-05 1996-06-04 A device for delivering a preselected molecule into systemic circulation Expired - Fee Related CA2222613C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/461,042 1995-06-05
US08/461,042 US5704910A (en) 1995-06-05 1995-06-05 Implantable device and use therefor
PCT/US1996/008524 WO1996039098A1 (en) 1995-06-05 1996-06-04 A device for delivering a preselected molecule into the system circulation

Publications (2)

Publication Number Publication Date
CA2222613A1 CA2222613A1 (en) 1996-12-12
CA2222613C true CA2222613C (en) 2001-08-07

Family

ID=23830999

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002222613A Expired - Fee Related CA2222613C (en) 1995-06-05 1996-06-04 A device for delivering a preselected molecule into systemic circulation

Country Status (8)

Country Link
US (5) US5704910A (2)
EP (2) EP1486182A3 (2)
JP (1) JP3878672B2 (2)
AT (1) ATE274869T1 (2)
AU (1) AU716897B2 (2)
CA (1) CA2222613C (2)
DE (1) DE69633278T2 (2)
WO (1) WO1996039098A1 (2)

Families Citing this family (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5704910A (en) * 1995-06-05 1998-01-06 Nephros Therapeutics, Inc. Implantable device and use therefor
US6416510B1 (en) 1997-03-13 2002-07-09 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
US6547787B1 (en) 1997-03-13 2003-04-15 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
US6409674B1 (en) * 1998-09-24 2002-06-25 Data Sciences International, Inc. Implantable sensor with wireless communication
US20020188207A1 (en) * 1998-01-08 2002-12-12 Jacob Richter Anchor for sensor implanted in a bodily lumen
US6206914B1 (en) * 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6102887A (en) * 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
CA2340276A1 (en) * 1998-08-28 2000-03-09 Duke University Adenoviruses deleted in the iva2, 100k and/or preterminal protein sequences
US7314477B1 (en) 1998-09-25 2008-01-01 C.R. Bard Inc. Removable embolus blood clot filter and filter delivery unit
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US7044134B2 (en) * 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
US8016852B2 (en) * 1998-11-10 2011-09-13 Stryker Corporation Bioactive components for incorporation with vaso-occlusive members
US6187024B1 (en) 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US6713293B1 (en) * 1999-02-08 2004-03-30 Friedrich Grummt Encapsulated cells containing an amplified expression vector as a drug delivery device
US6080178A (en) * 1999-04-20 2000-06-27 Meglin; Allen J. Vena cava filter
US6436120B1 (en) 1999-04-20 2002-08-20 Allen J. Meglin Vena cava filter
WO2001007059A1 (en) * 1999-07-21 2001-02-01 University Of Southern California Matrix-targeted fusion polypeptides for tissue regeneration and wound healing
US6770468B1 (en) 1999-09-14 2004-08-03 Genzyme Glycobiology Research Institute, Inc. Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway
US6537785B1 (en) 1999-09-14 2003-03-25 Genzyme Glycobiology Research Institute, Inc. Methods of treating lysosomal storage diseases
US6994092B2 (en) * 1999-11-08 2006-02-07 Ev3 Sunnyvale, Inc. Device for containing embolic material in the LAA having a plurality of tissue retention structures
US6217600B1 (en) 2000-01-26 2001-04-17 Scimed Life Systems, Inc. Thrombus filter with break-away anchor members
US6342063B1 (en) 2000-01-26 2002-01-29 Scimed Life Systems, Inc. Device and method for selectively removing a thrombus filter
US6478776B1 (en) 2000-04-05 2002-11-12 Biocardia, Inc. Implant delivery catheter system and methods for its use
US7651696B2 (en) * 2000-08-25 2010-01-26 Nexeon Medical Systems, Inc. Implantable device for treating disease states and methods of using same
US6740331B1 (en) 2000-08-25 2004-05-25 Global Gene Therapies, Inc. Apparatus for the delivery of drugs or gene therapy into a patient's vasculature and methods of use
US20020090388A1 (en) * 2000-12-01 2002-07-11 Humes H. David Intravascular drug delivery device and use therefor
CA2430554A1 (en) * 2000-12-01 2002-07-25 Nephros Therapeutics, Inc. Intravascular blood conditioning device and use thereof
US6867183B2 (en) * 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US20040005309A1 (en) * 2002-05-29 2004-01-08 Symbiontics, Inc. Targeted therapeutic proteins
US7629309B2 (en) * 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
ATE384736T1 (de) 2001-04-30 2008-02-15 Zystor Therapeutics Inc Subzelluläres targeting von therapeutischen proteinen
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US6828297B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
WO2003000314A2 (en) 2001-06-20 2003-01-03 The Regents Of The University Of California Hemodialysis system and method
US7247313B2 (en) 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
EP1281767A3 (en) * 2001-07-31 2003-05-28 Aladar A. Szalay Light emitting microorganisms and cells for diagnosis and therapy of tumors
ES2250690T3 (es) 2001-08-01 2006-04-16 Anecova Sa Dispositivo intrauterino y metodo para poner elementos activos dentro de dicho dispositivo.
US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
US20030073961A1 (en) * 2001-09-28 2003-04-17 Happ Dorrie M. Medical device containing light-protected therapeutic agent and a method for fabricating thereof
US20030072761A1 (en) * 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
US6592594B2 (en) 2001-10-25 2003-07-15 Spiration, Inc. Bronchial obstruction device deployment system and method
US20060292206A1 (en) 2001-11-26 2006-12-28 Kim Steven W Devices and methods for treatment of vascular aneurysms
US20030124652A1 (en) * 2001-12-21 2003-07-03 Novazyme Pharmaceuticals, Inc. Methods of producing high mannose glycoproteins in complex carbohydrate deficient cells
US6905856B2 (en) * 2001-12-21 2005-06-14 Genzyme Glycobiology Research Institute, Inc. Soluble GlcNAc phosphotransferase
US6800472B2 (en) * 2001-12-21 2004-10-05 Genzyme Glycobiology Research Institute, Inc. Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase
US9204956B2 (en) 2002-02-20 2015-12-08 C. R. Bard, Inc. IVC filter with translating hooks
US6929637B2 (en) * 2002-02-21 2005-08-16 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US7442546B2 (en) 2002-03-15 2008-10-28 The Regents Of The University Of Michigan Method of modulating inflammatory response
US20030216769A1 (en) 2002-05-17 2003-11-20 Dillard David H. Removable anchored lung volume reduction devices and methods
US20030181922A1 (en) 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20030195385A1 (en) * 2002-04-16 2003-10-16 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US7695427B2 (en) * 2002-04-26 2010-04-13 Torax Medical, Inc. Methods and apparatus for treating body tissue sphincters and the like
US20050197715A1 (en) * 2002-04-26 2005-09-08 Torax Medical, Inc. Methods and apparatus for implanting devices into non-sterile body lumens or organs
US20030228261A1 (en) * 2002-06-05 2003-12-11 Aladar Szalay Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
EP1369491A1 (en) * 2002-06-05 2003-12-10 Aladar A. Szalay Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
AU2003236521A1 (en) 2002-06-13 2003-12-31 Nobex Corporation Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US7005137B1 (en) 2002-06-21 2006-02-28 Advanceed Cardiovascular Systems, Inc. Coating for implantable medical devices
US7396539B1 (en) 2002-06-21 2008-07-08 Advanced Cardiovascular Systems, Inc. Stent coatings with engineered drug release rate
US7491233B1 (en) 2002-07-19 2009-02-17 Advanced Cardiovascular Systems Inc. Purified polymers for coatings of implantable medical devices
US7303575B2 (en) * 2002-08-01 2007-12-04 Lumen Biomedical, Inc. Embolism protection devices
AU2003267164A1 (en) * 2002-09-12 2004-04-30 Cook Incorporated Retrievable filter
US7481821B2 (en) 2002-11-12 2009-01-27 Thomas J. Fogarty Embolization device and a method of using the same
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
AU2003297534A1 (en) * 2002-12-24 2004-07-22 Ovion, Inc. Contraceptive device and delivery system
US7166458B2 (en) * 2003-01-07 2007-01-23 Bio Tex, Inc. Assay and method for analyte sensing by detecting efficiency of radiation conversion
US20040260382A1 (en) * 2003-02-12 2004-12-23 Fogarty Thomas J. Intravascular implants and methods of using the same
WO2004075855A2 (en) 2003-02-26 2004-09-10 Biomed Solutions, Llc Process for in vivo treatment of specific biological targets in bodily fluid
US7100616B2 (en) 2003-04-08 2006-09-05 Spiration, Inc. Bronchoscopic lung volume reduction method
US8791171B2 (en) * 2003-05-01 2014-07-29 Abbott Cardiovascular Systems Inc. Biodegradable coatings for implantable medical devices
US7563454B1 (en) 2003-05-01 2009-07-21 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices
US8239045B2 (en) * 2003-06-04 2012-08-07 Synecor Llc Device and method for retaining a medical device within a vessel
EP1633434B1 (en) * 2003-06-04 2014-11-19 Synecor Intravascular electrophysiological system
US7617007B2 (en) * 2003-06-04 2009-11-10 Synecor Llc Method and apparatus for retaining medical implants within body vessels
US7082336B2 (en) * 2003-06-04 2006-07-25 Synecor, Llc Implantable intravascular device for defibrillation and/or pacing
EP1644492B1 (en) * 2003-06-18 2009-01-07 Genelux Corporation Modified recombinant vaccinia viruses, uses thereof
CN1812746B (zh) * 2003-06-27 2011-07-06 孕体有限公司 用于阻塞体腔和/或用于递送治疗剂的方法和装置
US8048042B2 (en) * 2003-07-22 2011-11-01 Medtronic Vascular, Inc. Medical articles incorporating surface capillary fiber
US7879062B2 (en) * 2003-07-22 2011-02-01 Lumen Biomedical, Inc. Fiber based embolism protection device
US7662143B2 (en) * 2003-07-29 2010-02-16 Boston Scientific Scimed, Inc. Apparatus and method for treating intravascular disease
US7896898B2 (en) * 2003-07-30 2011-03-01 Boston Scientific Scimed, Inc. Self-centering blood clot filter
US7533671B2 (en) 2003-08-08 2009-05-19 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US7056286B2 (en) * 2003-11-12 2006-06-06 Adrian Ravenscroft Medical device anchor and delivery system
EP1701766A2 (en) * 2003-12-12 2006-09-20 Synecor, LLC Implantable medical device having pre-implant exoskeleton
US7704266B2 (en) 2004-01-22 2010-04-27 Rex Medical, L.P. Vein filter
US7976562B2 (en) 2004-01-22 2011-07-12 Rex Medical, L.P. Method of removing a vein filter
US9510929B2 (en) 2004-01-22 2016-12-06 Argon Medical Devices, Inc. Vein filter
US8162972B2 (en) 2004-01-22 2012-04-24 Rex Medical, Lp Vein filter
CN1922313B (zh) * 2004-02-10 2011-10-26 生物马林医药公司 酸性α-糖苷酶及其片段
JP4680939B2 (ja) * 2004-02-10 2011-05-11 シネコー・エルエルシー 治療薬用脈管内送達システム
US8764729B2 (en) * 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
BRPI0513508B1 (pt) 2004-07-19 2021-06-01 Biocon Limited Conjugados de insulina-oligômero, formulações e usos desses
US7704267B2 (en) 2004-08-04 2010-04-27 C. R. Bard, Inc. Non-entangling vena cava filter
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
EP2298236B1 (en) * 2004-09-27 2013-11-06 Rex Medical, L.P. Vein filter
US8795315B2 (en) 2004-10-06 2014-08-05 Cook Medical Technologies Llc Emboli capturing device having a coil and method for capturing emboli
CA2583061C (en) 2004-10-06 2015-02-17 Kwang Guan Tay Antibody production method
US20060079927A1 (en) * 2004-10-08 2006-04-13 Medtronic Vascular, Inc., A Delaware Corporation Detachable joint catheter and method
EP1809374A4 (en) * 2004-10-12 2008-09-10 Closed Loop Therapies Ltd IMPLANTABLE METHODS AND DEVICES FOR TREATING SUPRAVENTRICULAR ARRHYTHMIAS
US7794473B2 (en) * 2004-11-12 2010-09-14 C.R. Bard, Inc. Filter delivery system
US8267954B2 (en) * 2005-02-04 2012-09-18 C. R. Bard, Inc. Vascular filter with sensing capability
US8169892B2 (en) * 2005-02-08 2012-05-01 Nokia Corporation HARQ failure indication over IUB-interface
US8945169B2 (en) 2005-03-15 2015-02-03 Cook Medical Technologies Llc Embolic protection device
US8221446B2 (en) 2005-03-15 2012-07-17 Cook Medical Technologies Embolic protection device
US8574259B2 (en) * 2005-05-10 2013-11-05 Lifescreen Sciences Llc Intravascular filter with drug reservoir
US12115057B2 (en) 2005-05-12 2024-10-15 C.R. Bard, Inc. Tubular filter
US7967838B2 (en) 2005-05-12 2011-06-28 C. R. Bard, Inc. Removable embolus blood clot filter
US8109962B2 (en) 2005-06-20 2012-02-07 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
US7850708B2 (en) 2005-06-20 2010-12-14 Cook Incorporated Embolic protection device having a reticulated body with staggered struts
US7766934B2 (en) 2005-07-12 2010-08-03 Cook Incorporated Embolic protection device with an integral basket and bag
US7771452B2 (en) 2005-07-12 2010-08-10 Cook Incorporated Embolic protection device with a filter bag that disengages from a basket
US8187298B2 (en) 2005-08-04 2012-05-29 Cook Medical Technologies Llc Embolic protection device having inflatable frame
CA2616818C (en) 2005-08-09 2014-08-05 C.R. Bard, Inc. Embolus blood clot filter and delivery system
US7972359B2 (en) 2005-09-16 2011-07-05 Atritech, Inc. Intracardiac cage and method of delivering same
US8377092B2 (en) 2005-09-16 2013-02-19 Cook Medical Technologies Llc Embolic protection device
US8632562B2 (en) 2005-10-03 2014-01-21 Cook Medical Technologies Llc Embolic protection device
US8182508B2 (en) 2005-10-04 2012-05-22 Cook Medical Technologies Llc Embolic protection device
US8252017B2 (en) 2005-10-18 2012-08-28 Cook Medical Technologies Llc Invertible filter for embolic protection
US8216269B2 (en) 2005-11-02 2012-07-10 Cook Medical Technologies Llc Embolic protection device having reduced profile
US8152831B2 (en) 2005-11-17 2012-04-10 Cook Medical Technologies Llc Foam embolic protection device
US9131999B2 (en) 2005-11-18 2015-09-15 C.R. Bard Inc. Vena cava filter with filament
US20070135826A1 (en) 2005-12-01 2007-06-14 Steve Zaver Method and apparatus for delivering an implant without bias to a left atrial appendage
US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8278094B2 (en) 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US20090081296A1 (en) * 2006-02-02 2009-03-26 Humes H David Extracorporeal cell-based therapeutic device and delivery system
EP1989144A4 (en) 2006-02-02 2014-01-29 Innovative Bio Therapies EXTRACORPOREAL THERAPEUTIC DEVICE AND DELIVERY SYSTEM BASED ON CELLS
US8235047B2 (en) * 2006-03-30 2012-08-07 Conceptus, Inc. Methods and devices for deployment into a lumen
US7691151B2 (en) 2006-03-31 2010-04-06 Spiration, Inc. Articulable Anchor
US10188496B2 (en) 2006-05-02 2019-01-29 C. R. Bard, Inc. Vena cava filter formed from a sheet
US20070265655A1 (en) * 2006-05-09 2007-11-15 Boston Scientific Scimed, Inc. Embolic protection filter with enhanced stability within a vessel
US20080090765A1 (en) * 2006-05-25 2008-04-17 The Trustees Of Columbia University In The City Of New York Compositions for modulating growth of embryonic and adult kidney tissue and uses for treating kidney damage
US9326842B2 (en) 2006-06-05 2016-05-03 C. R . Bard, Inc. Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
US20080097377A1 (en) * 2006-06-13 2008-04-24 The Florida International University Board Of Trustees Temperature-controlled catheter system and method
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
US10076401B2 (en) 2006-08-29 2018-09-18 Argon Medical Devices, Inc. Vein filter
US20080071307A1 (en) 2006-09-19 2008-03-20 Cook Incorporated Apparatus and methods for in situ embolic protection
US20090117091A1 (en) * 2006-11-13 2009-05-07 Lebowitz Jonathan Methods for treating pompe disease
EP2153803B1 (en) * 2006-12-07 2011-10-26 Mallinckrodt Inc. Medical devices for localized drug delivery
US20080215072A1 (en) * 2007-02-15 2008-09-04 Graham Kelly Methods and apparatus for utilization of barbed sutures in human tissue including a method for eliminating or improving blood flow in veins
US9901434B2 (en) 2007-02-27 2018-02-27 Cook Medical Technologies Llc Embolic protection device including a Z-stent waist band
US8795351B2 (en) 2007-04-13 2014-08-05 C.R. Bard, Inc. Migration resistant embolic filter
US8007470B2 (en) * 2007-07-10 2011-08-30 Cook Medical Technologies Llc Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall
WO2009015341A1 (en) * 2007-07-25 2009-01-29 Mick Radio-Nuclear Instruments, Inc. Seed anchor
US8419748B2 (en) 2007-09-14 2013-04-16 Cook Medical Technologies Llc Helical thrombus removal device
US8252018B2 (en) 2007-09-14 2012-08-28 Cook Medical Technologies Llc Helical embolic protection device
US9138307B2 (en) 2007-09-14 2015-09-22 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US8136230B2 (en) 2007-10-12 2012-03-20 Spiration, Inc. Valve loader method, system, and apparatus
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
JP5868594B2 (ja) * 2007-10-16 2016-02-24 バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ 経口投与可能な固形医薬組成物及びそのプロセス
US9023063B2 (en) 2008-04-17 2015-05-05 Apollo Endosurgery, Inc. Implantable access port device having a safety cap
RU2464048C2 (ru) 2008-04-17 2012-10-20 Аллерган, Инк. Имплантируемый порт доступа и система его крепления
HRP20170698T1 (hr) 2008-05-07 2017-09-22 Biomarin Pharmaceutical Inc. Lizosomski usmjereni peptidi i njihove uporabe
DE102008002397A1 (de) 2008-06-12 2009-12-17 Biotronik Vi Patent Ag Implantierbare Vorrichtung
CN102171332A (zh) * 2008-06-18 2011-08-31 创新生物制剂疗法公司 促进肾前体细胞增殖的方法
US8388644B2 (en) 2008-12-29 2013-03-05 Cook Medical Technologies Llc Embolic protection device and method of use
US8715732B2 (en) * 2009-01-05 2014-05-06 Cornell University Nucleic acid hydrogel via rolling circle amplification
US20120141547A1 (en) * 2009-04-03 2012-06-07 Feng Zhao Methods of making cell sheets, tissue sheets and tissue engineered blood vessels
AU2010248992B2 (en) * 2009-05-15 2014-11-27 Intersect Ent, Inc. Expandable devices and methods therefor
US20100303882A1 (en) * 2009-05-26 2010-12-02 Mallinckrodt Inc. Medical Devices for Localized Drug Delivery
EP2475376B1 (en) 2009-06-17 2016-03-30 BioMarin Pharmaceutical Inc. Formulations for lysosomal enzymes
US8809311B2 (en) * 2009-08-10 2014-08-19 Darlene McCord Nutritional supplements
ES2717424T3 (es) 2009-07-29 2019-06-21 Bard Inc C R Filtro tubular
US8708979B2 (en) 2009-08-26 2014-04-29 Apollo Endosurgery, Inc. Implantable coupling device
US8715158B2 (en) 2009-08-26 2014-05-06 Apollo Endosurgery, Inc. Implantable bottom exit port
US8506532B2 (en) 2009-08-26 2013-08-13 Allergan, Inc. System including access port and applicator tool
EP2496189A4 (en) * 2009-11-04 2016-05-11 Nitinol Devices And Components Inc DESIGN FOR A STENT WITH AN ALTERNATIVE RINGARY BRIDGE AND USE METHOD THEREFOR
US8882728B2 (en) 2010-02-10 2014-11-11 Apollo Endosurgery, Inc. Implantable injection port
US20130023823A1 (en) * 2010-03-10 2013-01-24 University Of Florida Research Foundation Inc. Implantable therapeutic device and methods of making
US8992415B2 (en) 2010-04-30 2015-03-31 Apollo Endosurgery, Inc. Implantable device to protect tubing from puncture
US20110270021A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Electronically enhanced access port for a fluid filled implant
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US20120041258A1 (en) 2010-08-16 2012-02-16 Allergan, Inc. Implantable access port system
US20120065460A1 (en) 2010-09-14 2012-03-15 Greg Nitka Implantable access port system
EP2624791B1 (en) * 2010-10-08 2017-06-21 Confluent Medical Technologies, Inc. Alternating circumferential bridge stent design
US9395286B2 (en) * 2011-01-04 2016-07-19 Massachusetts Institute Of Technology Device and method for sampling bodily fluid for medical analytes in ultra low concentrations
US8821373B2 (en) 2011-05-10 2014-09-02 Apollo Endosurgery, Inc. Directionless (orientation independent) needle injection port
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
US20130030369A1 (en) * 2011-07-27 2013-01-31 Vascular Solutions, Inc. Vascular introducer including expandable passage member
US8801597B2 (en) 2011-08-25 2014-08-12 Apollo Endosurgery, Inc. Implantable access port with mesh attachment rivets
US9199069B2 (en) 2011-10-20 2015-12-01 Apollo Endosurgery, Inc. Implantable injection port
US8858421B2 (en) 2011-11-15 2014-10-14 Apollo Endosurgery, Inc. Interior needle stick guard stems for tubes
US9089395B2 (en) 2011-11-16 2015-07-28 Appolo Endosurgery, Inc. Pre-loaded septum for use with an access port
AU2013204200B2 (en) 2012-10-11 2016-10-20 Brandeis University Treatment of amyotrophic lateral sclerosis
US9414752B2 (en) 2012-11-09 2016-08-16 Elwha Llc Embolism deflector
EP2968877B1 (en) 2013-03-14 2020-01-01 Intersect ENT, Inc. Systems and devices for treating a sinus condition
EP2813234A1 (en) * 2013-06-11 2014-12-17 Erytech Pharma Composition of erythrocytes encapsulating phenylalanine hydroxylase and therapeutic use thereof
AU2016235152B2 (en) * 2015-03-23 2020-09-03 The Regents Of The University Of California Thin film cell encapsulation devices
US9867974B2 (en) * 2015-06-01 2018-01-16 Wisconsin Alumni Research Foundation Microfluidic device for multiplexed point source administration of compounds
WO2018200891A1 (en) 2017-04-27 2018-11-01 Boston Scientific Scimed, Inc. Occlusive medical device with fabric retention barb
EP3829603A4 (en) * 2018-07-27 2022-04-27 Washington University CELL-EMBEDDED VASCULAR GRAFT FOR TRANSPLANTATION
DE102018006061A1 (de) * 2018-08-01 2020-02-06 Universität Duisburg-Essen Implantat
EP3840670B1 (en) 2018-08-21 2023-11-15 Boston Scientific Scimed, Inc. Projecting member with barb for cardiovascular devices
EP3998962B1 (en) 2019-07-17 2024-05-08 Boston Scientific Scimed, Inc. Left atrial appendage implant with continuous covering
EP3986284B1 (en) 2019-08-30 2025-05-14 Boston Scientific Scimed, Inc. Left atrial appendage implant with sealing disk
US20210093435A1 (en) 2019-09-27 2021-04-01 Isla Technologies, Inc. Bioartificial pancreas
EP4609806A3 (en) 2020-03-24 2025-11-26 Boston Scientific Scimed, Inc. Medical system for treating a left atrial appendage
CN116685276A (zh) 2020-11-30 2023-09-01 波士顿科学医学有限公司 植入式无源平均压力传感器
WO2022155344A1 (en) 2021-01-14 2022-07-21 Boston Scientific Scimed, Inc. Medical system for treating a left atrial appendage
US12383201B2 (en) 2021-02-03 2025-08-12 Boston Scientific Scimed, Inc. Medical system for treating a left atrial appendage
WO2022271832A1 (en) 2021-06-22 2022-12-29 Boston Scientific Scimed, Inc. Left atrial appendage implant
FR3124695B1 (fr) * 2021-06-30 2023-06-30 Univ Grenoble Alpes Matrice de réception de cellules pancréatiques et dispositif amélioré de pancréas artificiel
JP7690067B2 (ja) 2021-07-08 2025-06-09 ボストン サイエンティフィック サイムド，インコーポレイテッド 左心耳閉鎖デバイス
WO2023038929A1 (en) 2021-09-08 2023-03-16 Boston Scientific Scimed, Inc. Occlusive implant with multi-sharpness split tip soft tissue anchors
EP4568616A2 (en) * 2022-08-09 2025-06-18 The General Hospital Corporation Endovascular biologic stent
US12502178B2 (en) 2022-08-16 2025-12-23 Boston Scientific Scimed, Inc. Medical device for occluding a left atrial appendage
KR20250102135A (ko) 2022-10-11 2025-07-04 메이라지티엑스 유케이 Ii 리미티드 Upf1 발현 작제물
WO2024079530A2 (en) 2022-10-11 2024-04-18 Meiragtx Uk Ii Limited Nucleic acid regulatory elements for gene expression in the muscle and methods of use

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313289A (en) * 1964-06-23 1967-04-11 Frank A Kapral Implant chamber
US3952747A (en) * 1974-03-28 1976-04-27 Kimmell Jr Garman O Filter and filter insertion instrument
US4309776A (en) * 1980-05-13 1982-01-12 Ramon Berguer Intravascular implantation device and method of using the same
US4393133A (en) * 1980-06-12 1983-07-12 The Wistar Institute Of Anatomy And Biology Human hepatoma derived cell line, process for preparation thereof, and uses therefor
US4378016A (en) * 1981-07-15 1983-03-29 Biotek, Inc. Artificial endocrine gland containing hormone-producing cells
US4586922A (en) * 1981-10-09 1986-05-06 Alza Corporation Intravenous system for delivering a beneficial agent
US4479796A (en) * 1982-11-15 1984-10-30 Medtronic, Inc. Self-regenerating drug administration device
US4494531A (en) * 1982-12-06 1985-01-22 Cook, Incorporated Expandable blood clot filter
US5104399A (en) * 1986-12-10 1992-04-14 Endovascular Technologies, Inc. Artificial graft and implantation method
GB8422876D0 (en) * 1984-09-11 1984-10-17 Secr Defence Silicon implant devices
DE3447202A1 (de) * 1984-12-22 1986-07-10 CYTOMED Medizintechnik GmbH, 8750 Aschaffenburg Implantierbarer, intravasaler katheter fuer die dauermedikation von pharmaka
SE447061B (sv) * 1985-06-10 1986-10-27 Medinvent Sa Inforingsanordning, spec for implantering i en levande organism
US4793348A (en) * 1986-11-15 1988-12-27 Palmaz Julio C Balloon expandable vena cava filter to prevent migration of lower extremity venous clots into the pulmonary circulation
FR2606641B1 (fr) * 1986-11-17 1991-07-12 Promed Dispositif filtrant pour caillots sanguins
US5026365A (en) * 1987-04-29 1991-06-25 The University Of Massachusetts Method and apparatus for therapeutically treating immunological disorders and disease states
US4817600A (en) * 1987-05-22 1989-04-04 Medi-Tech, Inc. Implantable filter
US4911717A (en) * 1987-06-18 1990-03-27 Gaskill Iii Harold V Intravasular artificial organ
US5182111A (en) * 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US5487739A (en) * 1987-11-17 1996-01-30 Brown University Research Foundation Implantable therapy systems and methods
US4936823A (en) * 1988-05-04 1990-06-26 Triangle Research And Development Corp. Transendoscopic implant capsule
US4832055A (en) * 1988-07-08 1989-05-23 Palestrant Aubrey M Mechanically locking blood clot filter
US5152743A (en) 1988-08-05 1992-10-06 Healthdyne, Inc. Apparatus and method for selective separation of blood cholesterol
US5164186A (en) * 1988-10-13 1992-11-17 Kabushikigaisha Ars Japan Drug-releaser
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
JPH04507041A (ja) * 1988-12-13 1992-12-10 アメリカ合衆国 遺伝工学により修飾された内皮細胞およびその利用方法
US5152777A (en) * 1989-01-25 1992-10-06 Uresil Corporation Device and method for providing protection from emboli and preventing occulsion of blood vessels
US5059205A (en) * 1989-09-07 1991-10-22 Boston Scientific Corporation Percutaneous anti-migration vena cava filter
DE3941873A1 (de) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen
US5314471A (en) * 1991-07-24 1994-05-24 Baxter International Inc. Tissue inplant systems and methods for sustaining viable high cell densities within a host
US5053008A (en) * 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5147379A (en) * 1990-11-26 1992-09-15 Louisiana State University And Agricultural And Mechanical College Insertion instrument for vena cava filter
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
US5391164A (en) * 1991-05-03 1995-02-21 Giampapa; Vincent C. Subcutaneous implantable multiple-agent delivery system
US5350398A (en) * 1991-05-13 1994-09-27 Dusan Pavcnik Self-expanding filter for percutaneous insertion
WO1993006878A1 (en) * 1991-10-11 1993-04-15 Boston Scientific Corporation Catheter introducer sheath assembly
FR2683449A1 (fr) * 1991-11-08 1993-05-14 Cardon Alain Endoprothese pour implantation transluminale.
US5304120A (en) * 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
FR2697995B1 (fr) * 1992-11-19 1994-12-30 Celsa Lg Dispositif amovible de filtration sanguine, à rigidité variable, implantable dans le corps d'un patient et autorisant l'injection d'un produit traitant.
EP0604022A1 (en) * 1992-12-22 1994-06-29 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method for its manufacture
FR2699809B1 (fr) * 1992-12-28 1995-02-17 Celsa Lg Dispositif pouvant constituer sélectivement un filtre sanguin temporaire.
AU675505B2 (en) * 1993-01-08 1997-02-06 Miravant Systems, Inc. Medicament dispensing stents
US5645829A (en) * 1993-06-18 1997-07-08 Beth Israel Hospital Association Mesothelial cell gene therapy
US5961923A (en) 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US5704910A (en) * 1995-06-05 1998-01-06 Nephros Therapeutics, Inc. Implantable device and use therefor
US6283951B1 (en) 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US5902336A (en) 1996-10-15 1999-05-11 Mirimedical, Inc. Implantable device and method for removing fluids from the blood of a patient method for implanting such a device and method for treating a patient experiencing renal failure
US6022333A (en) 1997-05-01 2000-02-08 S.L.I.M. Tech, Ltd. Method and system for removing materials from lymphatic and other fluids
CA2430554A1 (en) 2000-12-01 2002-07-25 Nephros Therapeutics, Inc. Intravascular blood conditioning device and use thereof

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US6572605B1 (en) 2003-06-03
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US6716208B2 (en) 2004-04-06
US5704910A (en) 1998-01-06
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EP1486182A3 (en) 2006-03-15
DE69633278T2 (de) 2006-08-17
US20010001817A1 (en) 2001-05-24
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DE69633278D1 (de) 2004-10-07
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US20050019370A1 (en) 2005-01-27
ATE274869T1 (de) 2004-09-15

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