CA2225450A1 - Proteine kinase associee au recepteur de l'interleukine-1 et dosages - Google Patents
Proteine kinase associee au recepteur de l'interleukine-1 et dosagesInfo
- Publication number
- CA2225450A1 CA2225450A1 CA002225450A CA2225450A CA2225450A1 CA 2225450 A1 CA2225450 A1 CA 2225450A1 CA 002225450 A CA002225450 A CA 002225450A CA 2225450 A CA2225450 A CA 2225450A CA 2225450 A1 CA2225450 A1 CA 2225450A1
- Authority
- CA
- Canada
- Prior art keywords
- assays
- receptor
- associated protein
- interleukin
- protein kinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 2
- 108060006633 protein kinase Proteins 0.000 title abstract 2
- 102000019223 Interleukin-1 receptor Human genes 0.000 title 1
- 108050006617 Interleukin-1 receptor Proteins 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 101710199015 Interleukin-1 receptor-associated kinase 1 Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000000589 Interleukin-1 Human genes 0.000 abstract 1
- 108010002352 Interleukin-1 Proteins 0.000 abstract 1
- 102100036342 Interleukin-1 receptor-associated kinase 1 Human genes 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 150000002611 lead compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 238000003566 phosphorylation assay Methods 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49400695A | 1995-06-23 | 1995-06-23 | |
| US08/494,006 | 1995-06-23 | ||
| PCT/US1996/009193 WO1997000690A1 (fr) | 1995-06-23 | 1996-06-05 | Proteine kinase associee au recepteur de l'interleukine-1 et dosages |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2225450A1 true CA2225450A1 (fr) | 1997-01-09 |
| CA2225450C CA2225450C (fr) | 2001-05-29 |
Family
ID=23962617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225450A Expired - Fee Related CA2225450C (fr) | 1995-06-23 | 1996-06-05 | Proteine kinase associee au recepteur de l'interleukine-1 et dosages |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0839045A4 (fr) |
| JP (1) | JPH11509085A (fr) |
| AU (1) | AU702844B2 (fr) |
| CA (1) | CA2225450C (fr) |
| WO (1) | WO1997000690A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5932425A (en) * | 1997-02-18 | 1999-08-03 | Signal Pharmaceuticals, Inc. | Compositions and methods for modulating cellular NF-κB activation |
| US5965421A (en) | 1997-11-26 | 1999-10-12 | Human Genome Sciences, Inc. | Human IRAK-2 |
| US6262228B1 (en) * | 1998-08-17 | 2001-07-17 | Tularik Inc. | IRAK3 polypeptides and methods |
| GB9913180D0 (en) * | 1999-06-08 | 1999-08-04 | Glaxo Group Ltd | Interleukin-1 receptor associated kinases |
| WO2002040680A2 (fr) * | 2000-11-17 | 2002-05-23 | The Burnham Institute | Nouvelles proteines du domaine de mort cellulaire |
| US6965023B2 (en) | 2000-11-17 | 2005-11-15 | The Burnham Institute | Death domain proteins |
| WO2005052132A2 (fr) * | 2003-11-24 | 2005-06-09 | Exelixis, Inc | Utilisation de modulateurs de la morphogenese de ramification comme genes modificateurs de la morphogenese de ramification et leurs procedes d'utilisation |
-
1996
- 1996-06-05 WO PCT/US1996/009193 patent/WO1997000690A1/fr not_active Ceased
- 1996-06-05 JP JP9503857A patent/JPH11509085A/ja not_active Ceased
- 1996-06-05 AU AU61766/96A patent/AU702844B2/en not_active Ceased
- 1996-06-05 CA CA002225450A patent/CA2225450C/fr not_active Expired - Fee Related
- 1996-06-05 EP EP96919140A patent/EP0839045A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11509085A (ja) | 1999-08-17 |
| CA2225450C (fr) | 2001-05-29 |
| EP0839045A4 (fr) | 1999-06-09 |
| EP0839045A1 (fr) | 1998-05-06 |
| AU6176696A (en) | 1997-01-22 |
| AU702844B2 (en) | 1999-03-04 |
| WO1997000690A1 (fr) | 1997-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |