CA2235393C - Compositions therapeutiques anti-angiogenese et procedes associes - Google Patents
Compositions therapeutiques anti-angiogenese et procedes associes Download PDFInfo
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- CA2235393C CA2235393C CA 2235393 CA2235393A CA2235393C CA 2235393 C CA2235393 C CA 2235393C CA 2235393 CA2235393 CA 2235393 CA 2235393 A CA2235393 A CA 2235393A CA 2235393 C CA2235393 C CA 2235393C
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- endostatin
- protein
- angiogenesis
- acid sequence
- endostatin protein
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Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention concerne un inhibiteur de la prolifération des cellules endothéliales, capable d'inhiber l'angiogenèse et de provoquer une régression des tumeurs. Cet inhibiteur est d'environ 20 kDa et il correspond à un fragment C-terminal du collagène de type XVIII. L'invention concerne également des thérapies permettant de traiter des maladies liées à l'angiogénèse.
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US583595P | 1995-10-23 | 1995-10-23 | |
| US60/005,835 | 1995-10-23 | ||
| US2307096P | 1996-08-02 | 1996-08-02 | |
| US60/023,070 | 1996-08-02 | ||
| US2626396P | 1996-09-17 | 1996-09-17 | |
| US60/026,263 | 1996-09-17 | ||
| US08/740,168 | 1996-10-22 | ||
| US08/740,168 US5854205A (en) | 1995-10-23 | 1996-10-22 | Therapeutic antiangiogenic compositions and methods |
| PCT/US1996/016925 WO1997015666A1 (fr) | 1995-10-23 | 1996-10-23 | Compositions therapeutiques anti-angiogenese et procedes associes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2235393A1 CA2235393A1 (fr) | 1997-05-01 |
| CA2235393C true CA2235393C (fr) | 2010-04-06 |
Family
ID=29408123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2235393 Expired - Lifetime CA2235393C (fr) | 1995-10-23 | 1996-10-23 | Compositions therapeutiques anti-angiogenese et procedes associes |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2235393C (fr) |
-
1996
- 1996-10-23 CA CA 2235393 patent/CA2235393C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2235393A1 (fr) | 1997-05-01 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20161024 |