CA2237581A1 - Proteines secretees par la salmonelle et utilisations de ces proteines - Google Patents

Proteines secretees par la salmonelle et utilisations de ces proteines Download PDF

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Publication number
CA2237581A1
CA2237581A1 CA002237581A CA2237581A CA2237581A1 CA 2237581 A1 CA2237581 A1 CA 2237581A1 CA 002237581 A CA002237581 A CA 002237581A CA 2237581 A CA2237581 A CA 2237581A CA 2237581 A1 CA2237581 A1 CA 2237581A1
Authority
CA
Canada
Prior art keywords
dna
ssp
seq
cell
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002237581A
Other languages
English (en)
Inventor
Samuel I. Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2237581A1 publication Critical patent/CA2237581A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255—Salmonella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention concerne des protéines sécrétées par la Salmonelle (Ssp), sensiblement pures, dont la sécrétion dépend de l'expression du gène PrgH. L'invention concerne en outre des procédés permettant de diagnostiquer une infection par la Salmonelle ainsi que des souches de vaccins vivants atténués par une sécrétion réduite de protéines Ssp.
CA002237581A 1995-11-14 1996-11-14 Proteines secretees par la salmonelle et utilisations de ces proteines Abandoned CA2237581A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US673395P 1995-11-14 1995-11-14
US60/006,733 1995-11-14

Publications (1)

Publication Number Publication Date
CA2237581A1 true CA2237581A1 (fr) 1997-05-22

Family

ID=21722306

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002237581A Abandoned CA2237581A1 (fr) 1995-11-14 1996-11-14 Proteines secretees par la salmonelle et utilisations de ces proteines

Country Status (4)

Country Link
EP (1) EP0939761A4 (fr)
AU (1) AU7738396A (fr)
CA (1) CA2237581A1 (fr)
WO (1) WO1997018225A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025171A1 (fr) * 2006-08-31 2008-03-06 The University Of British Columbia Vaccins et procédés pour le traitement ou la prévention d'infections bactériennes par des espèces salmonella chez un sujet vertébré

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69526377T2 (de) 1994-12-09 2002-11-07 Microscience Ltd Virulenzgene in der VGC2-Region von Salmonella
US6080849A (en) 1997-09-10 2000-06-27 Vion Pharmaceuticals, Inc. Genetically modified tumor-targeted bacteria with reduced virulence
WO1999013053A1 (fr) 1997-09-10 1999-03-18 Vion Pharmaceuticals, Inc. Bacteries a virulence reduite modifiees genetiquement ciblees sur des tumeurs
WO2000014240A2 (fr) 1998-09-04 2000-03-16 Creatogen Aktiengesellschaft Mutants attenues de spi2 de salmonelles utilises comme porteurs d'antigenes
GB9910812D0 (en) 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
US6962696B1 (en) 1999-10-04 2005-11-08 Vion Pharmaceuticals Inc. Compositions and methods for tumor-targeted delivery of effector molecules
US6605285B2 (en) 2000-03-29 2003-08-12 G.B. Pant University Of Agriculture & Technology Vaccine for protection of poultry against salmonellosis and a process for preparing the same
DE102005037796A1 (de) * 2005-08-07 2007-02-08 Tgc Biomics Gmbh Testsystem zum Nachweis von Salmonellen
US7833740B2 (en) 2005-08-07 2010-11-16 Tgc Biomics Gmbh Test system for detecting salmonella
US8703153B2 (en) 2008-06-16 2014-04-22 Prokarium Ltd. Salmonella vectored vaccines against Chlamydia and methods of use
US9597379B1 (en) 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
DE102010018085A1 (de) * 2010-04-23 2011-10-27 Bioserv Analytik Und Medizinprodukte Gmbh Verfahren zur Erkennung einer Salmonelleninfektion
US10548962B2 (en) 2012-10-22 2020-02-04 The Board Of Regents For Oklahoma State University Use of the salmonella SPP type III secretion proteins as a protective vaccination
US9950053B2 (en) 2012-10-22 2018-04-24 The Board Of Regents For Oklahoma State University Use of the Salmonella SPP type III secretion proteins as a protective vaccination
US20150238590A1 (en) * 2012-10-22 2015-08-27 The Board Of Regents For Oklahoma State University Use of the salmonella spp type iii secretion proteins as a protective vaccination
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695983A (en) * 1990-12-18 1997-12-09 The General Hospital Corporation Salmonella vaccines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008025171A1 (fr) * 2006-08-31 2008-03-06 The University Of British Columbia Vaccins et procédés pour le traitement ou la prévention d'infections bactériennes par des espèces salmonella chez un sujet vertébré

Also Published As

Publication number Publication date
WO1997018225A1 (fr) 1997-05-22
EP0939761A4 (fr) 2002-07-31
AU7738396A (en) 1997-06-05
EP0939761A1 (fr) 1999-09-08

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued