CA2245145A1 - Procede de traitement des troubles lies a la presence de peptide beta-amyloide au moyen de thyroliberine - Google Patents

Procede de traitement des troubles lies a la presence de peptide beta-amyloide au moyen de thyroliberine Download PDF

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Publication number
CA2245145A1
CA2245145A1 CA002245145A CA2245145A CA2245145A1 CA 2245145 A1 CA2245145 A1 CA 2245145A1 CA 002245145 A CA002245145 A CA 002245145A CA 2245145 A CA2245145 A CA 2245145A CA 2245145 A1 CA2245145 A1 CA 2245145A1
Authority
CA
Canada
Prior art keywords
releasing hormone
amyloid peptide
amyloid
thyrotropin releasing
analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002245145A
Other languages
English (en)
Inventor
Kimberly Sue Fuson
Patrick Cornelious May
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2245145A1 publication Critical patent/CA2245145A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/066TRH, thyroliberin, thyrotropin releasing hormone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention se rapporte à un procédé de traitement d'un trouble physiologique associé à la présence d'un peptide bêta-amyloïde chez un mammifère. Ledit procédé consiste à administrer à un mammifère ayant besoin d'un tel traitement, une quantité efficace de thyrolibérine (TRH), un analogue de thyrolibérine, ou un sel ou un bioprécurseur de thyrolibérine ou dudit analogue.
CA002245145A 1996-02-05 1997-02-05 Procede de traitement des troubles lies a la presence de peptide beta-amyloide au moyen de thyroliberine Abandoned CA2245145A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1112696P 1996-02-05 1996-02-05
US60/011,126 1996-02-05

Publications (1)

Publication Number Publication Date
CA2245145A1 true CA2245145A1 (fr) 1997-08-07

Family

ID=21748996

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002245145A Abandoned CA2245145A1 (fr) 1996-02-05 1997-02-05 Procede de traitement des troubles lies a la presence de peptide beta-amyloide au moyen de thyroliberine

Country Status (5)

Country Link
EP (1) EP0912602A4 (fr)
JP (1) JP2000505425A (fr)
AU (1) AU1757597A (fr)
CA (1) CA2245145A1 (fr)
WO (1) WO1997028184A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540574A (en) * 1975-05-23 1979-02-14 Takeda Chemical Industries Ltd Medicament for remedying schizophrenia
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
FR2585709B1 (fr) * 1985-08-05 1987-10-02 Adir Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2649110B1 (fr) * 1989-06-29 1994-10-21 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1237435B (it) * 1989-12-14 1993-06-04 Farmaco attivo nel ripristino della plasticita' neuronale.
FR2663336B1 (fr) * 1990-06-18 1992-09-04 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
EP0912602A1 (fr) 1999-05-06
WO1997028184A1 (fr) 1997-08-07
AU1757597A (en) 1997-08-22
EP0912602A4 (fr) 2002-09-11
JP2000505425A (ja) 2000-05-09

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Legal Events

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EEER Examination request
FZDE Dead