CA2246802C - Antigene combine a un cytomegalovirus humain et son utilisation - Google Patents
Antigene combine a un cytomegalovirus humain et son utilisation Download PDFInfo
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- CA2246802C CA2246802C CA002246802A CA2246802A CA2246802C CA 2246802 C CA2246802 C CA 2246802C CA 002246802 A CA002246802 A CA 002246802A CA 2246802 A CA2246802 A CA 2246802A CA 2246802 C CA2246802 C CA 2246802C
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- hcmv
- combined antigen
- antigen
- combined
- amino acid
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- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 230000036963 noncompetitive effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 108010077112 prolyl-proline Proteins 0.000 description 1
- 108010053725 prolylvaline Proteins 0.000 description 1
- 230000007420 reactivation Effects 0.000 description 1
- 230000010322 reactivation of latent virus Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000002764 solid phase assay Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne un antigène combiné présentant au moins trois parties de protéines de cytomégalovirus humain (HCMV). Cet antigène est caractérisé par une meilleure capacité à se lier aux anticorps spécifiques de ce cytomégalovirus, lui permettant d'être utilisé dans des dosages visant à détecter les anticorps spécifiques du cytomégalovirus et comme vaccin pour assurer une immunité de protection contre les maladies induites par le cytomégalovirus.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/605,541 US5800981A (en) | 1996-02-22 | 1996-02-22 | Human cytomegalovirus antigen and its use |
| US08/605,541 | 1996-02-22 | ||
| PCT/EP1997/000865 WO1997031117A2 (fr) | 1996-02-22 | 1997-02-20 | Antigene combine a un cytomegalovirus humain et son utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2246802A1 CA2246802A1 (fr) | 1997-08-28 |
| CA2246802C true CA2246802C (fr) | 2006-12-05 |
Family
ID=37560872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002246802A Expired - Fee Related CA2246802C (fr) | 1996-02-22 | 1997-02-20 | Antigene combine a un cytomegalovirus humain et son utilisation |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2246802C (fr) |
-
1997
- 1997-02-20 CA CA002246802A patent/CA2246802C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2246802A1 (fr) | 1997-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |