CA2262066C - Methode rapide pour determiner la clairance des proteines prions - Google Patents

Methode rapide pour determiner la clairance des proteines prions Download PDF

Info

Publication number
CA2262066C
CA2262066C CA 2262066 CA2262066A CA2262066C CA 2262066 C CA2262066 C CA 2262066C CA 2262066 CA2262066 CA 2262066 CA 2262066 A CA2262066 A CA 2262066A CA 2262066 C CA2262066 C CA 2262066C
Authority
CA
Canada
Prior art keywords
sample
western blot
protein
tse
proteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 2262066
Other languages
English (en)
Other versions
CA2262066A1 (fr
Inventor
Steve R. Petteway
Douglas C. Lee
Robert W. Kozak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Priority to CA 2262066 priority Critical patent/CA2262066C/fr
Publication of CA2262066A1 publication Critical patent/CA2262066A1/fr
Application granted granted Critical
Publication of CA2262066C publication Critical patent/CA2262066C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA 2262066 1999-02-22 1999-02-22 Methode rapide pour determiner la clairance des proteines prions Expired - Lifetime CA2262066C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2262066 CA2262066C (fr) 1999-02-22 1999-02-22 Methode rapide pour determiner la clairance des proteines prions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2262066 CA2262066C (fr) 1999-02-22 1999-02-22 Methode rapide pour determiner la clairance des proteines prions

Publications (2)

Publication Number Publication Date
CA2262066A1 CA2262066A1 (fr) 2000-08-22
CA2262066C true CA2262066C (fr) 2006-06-06

Family

ID=29555160

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2262066 Expired - Lifetime CA2262066C (fr) 1999-02-22 1999-02-22 Methode rapide pour determiner la clairance des proteines prions

Country Status (1)

Country Link
CA (1) CA2262066C (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1596199A1 (fr) * 2004-05-14 2005-11-16 Prionics AG Méthode de détection des formes pathogènes des protéines prions.
CN118745237B (zh) * 2024-06-04 2025-09-23 沧州市天津工业大学研究院 一种辣根过氧化物酶介导的表面引发制备表面印迹聚合物微球的方法及其应用

Also Published As

Publication number Publication date
CA2262066A1 (fr) 2000-08-22

Similar Documents

Publication Publication Date Title
Lee et al. Monitoring plasma processing steps with a sensitive Western blot assay for the detection of the prion protein
EP0891553B1 (fr) Methode de detection des encephalopathies spongiformes transmissibles
HUP0104890A2 (hu) Eljárás és készlet prion protein extrahálására
CA1146067A (fr) Methode de dosage immunologique en phase solide utilisant un anticorps anti-haptene marque
Barnard et al. The measurement of prion protein in bovine brain tissue using differential extraction and DELFIA® as a diagnostic test for BSE
Simon et al. The identification of disease-induced biomarkers in the urine of BSE infected cattle
US7504204B2 (en) Detection of transmissible spongiform encephalopathy (TSE) protein employing a highly sensitive Western blot assay and chemiluminescent detection system
CA2262066C (fr) Methode rapide pour determiner la clairance des proteines prions
US20020137114A1 (en) Method of detecting PrP protein and kits therefor
Lukan et al. TSE diagnostics: recent advances in immunoassaying prions
Nunnally It's a mad, mad, mad, mad cow: a review of analytical methodology for detecting BSE/TSE
AU2005246032B2 (en) Method for the detection of disease-related prion
Soutyrine et al. A novel approach for scrapie-associated prion (PrPSc) detection in blood using the competitive affinity of an aggregate-specific antibody and streptavidin to PrPSc
US20050089943A1 (en) Rapid method of determining clearance of prion protein
US7713515B2 (en) Methods and compositions for use in diagnosing and characterizing diseases involving abnormal apoptosis
Dabaghian et al. An immunoassay for the pathological form of the prion protein based on denaturation and time resolved fluorometry
Sandholm Development and evaluation of immunoassays for complement diagnostics
Benjamin et al. Evaluation of solid-phase immunofluorescence for quantitation of antibodies to herpes simplex virus and cytomegalovirus
Barnard et al. The diagnosis of transmissible spongiform encephalopathies using differential extraction and DELFIA
Lee An enzyme immunoassay for urinary albumin at low concentrations
Missler et al. Time-resolved immunofluorometric assay for the quantification of lipoprotein (a) in serum
Sachse et al. Role of variant Creutzfeldt‐Jakob disease for safety of treatment with blood components: screening of lymphatic tissue is a potential tool for risk assessment
Gilbert et al. Detection of residual donor leucocytes in leucoreduced red blood cell components using a fluorescence microplate assay
Sy The Diagnosis of Transmissible Spongiform Encephalopathies Using Differential
Alpert Mary Jo Schmerr

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190222