CA2263473C - Compositions antimicrobiennes a base d'argent - Google Patents
Compositions antimicrobiennes a base d'argent Download PDFInfo
- Publication number
- CA2263473C CA2263473C CA002263473A CA2263473A CA2263473C CA 2263473 C CA2263473 C CA 2263473C CA 002263473 A CA002263473 A CA 002263473A CA 2263473 A CA2263473 A CA 2263473A CA 2263473 C CA2263473 C CA 2263473C
- Authority
- CA
- Canada
- Prior art keywords
- silver
- ion complexes
- thiosulfate ion
- silver thiosulfate
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 262
- 229910052709 silver Inorganic materials 0.000 title claims abstract description 162
- 239000004332 silver Substances 0.000 title claims abstract description 162
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 138
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 title abstract description 111
- ZSILVJLXKHGNPL-UHFFFAOYSA-L S(=S)(=O)([O-])[O-].[Ag+2] Chemical compound S(=S)(=O)([O-])[O-].[Ag+2] ZSILVJLXKHGNPL-UHFFFAOYSA-L 0.000 claims abstract description 344
- 229940006280 thiosulfate ion Drugs 0.000 claims abstract description 338
- 238000000034 method Methods 0.000 claims abstract description 105
- 239000011159 matrix material Substances 0.000 claims abstract description 69
- 208000015181 infectious disease Diseases 0.000 claims abstract description 37
- -1 silver halides Chemical class 0.000 claims description 77
- 229920000642 polymer Polymers 0.000 claims description 63
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 27
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 26
- 239000003795 chemical substances by application Substances 0.000 claims description 26
- 239000004599 antimicrobial Substances 0.000 claims description 25
- 239000000843 powder Substances 0.000 claims description 24
- 230000000699 topical effect Effects 0.000 claims description 23
- 239000007787 solid Substances 0.000 claims description 17
- 229940003587 aquaphor Drugs 0.000 claims description 16
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims description 16
- 235000019271 petrolatum Nutrition 0.000 claims description 16
- MTZBBNMLMNBNJL-UHFFFAOYSA-N xipamide Chemical compound CC1=CC=CC(C)=C1NC(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1O MTZBBNMLMNBNJL-UHFFFAOYSA-N 0.000 claims description 15
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical class [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 claims description 13
- 239000003871 white petrolatum Substances 0.000 claims description 13
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 claims description 12
- 239000006071 cream Substances 0.000 claims description 12
- 230000000813 microbial effect Effects 0.000 claims description 12
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 claims description 12
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims description 11
- 229960003128 mupirocin Drugs 0.000 claims description 10
- 229930187697 mupirocin Natural products 0.000 claims description 10
- 150000003431 steroids Chemical class 0.000 claims description 10
- 230000003444 anaesthetic effect Effects 0.000 claims description 8
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims description 8
- 229960000890 hydrocortisone Drugs 0.000 claims description 8
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 7
- 229960004194 lidocaine Drugs 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims description 6
- TYMRLRRVMHJFTF-UHFFFAOYSA-N Mafenide Chemical compound NCC1=CC=C(S(N)(=O)=O)C=C1 TYMRLRRVMHJFTF-UHFFFAOYSA-N 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- 229960003260 chlorhexidine Drugs 0.000 claims description 6
- 229960003640 mafenide Drugs 0.000 claims description 6
- 229960000282 metronidazole Drugs 0.000 claims description 6
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 229930182555 Penicillin Natural products 0.000 claims description 5
- SYCBXBCPLUFJID-UHFFFAOYSA-N Pramoxine hydrochloride Chemical compound Cl.C1=CC(OCCCC)=CC=C1OCCCN1CCOCC1 SYCBXBCPLUFJID-UHFFFAOYSA-N 0.000 claims description 5
- 239000004098 Tetracycline Substances 0.000 claims description 5
- 229940019974 pramoxine hydrochloride Drugs 0.000 claims description 5
- 229960002180 tetracycline Drugs 0.000 claims description 5
- 235000019364 tetracycline Nutrition 0.000 claims description 5
- 229930101283 tetracycline Natural products 0.000 claims description 5
- 150000003522 tetracyclines Chemical class 0.000 claims description 5
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims description 4
- 239000004099 Chlortetracycline Substances 0.000 claims description 4
- MUQNGPZZQDCDFT-JNQJZLCISA-N Halcinonide Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CCl)[C@@]1(C)C[C@@H]2O MUQNGPZZQDCDFT-JNQJZLCISA-N 0.000 claims description 4
- XWALNWXLMVGSFR-HLXURNFRSA-N Methandrostenolone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@](C)(O)[C@@]1(C)CC2 XWALNWXLMVGSFR-HLXURNFRSA-N 0.000 claims description 4
- 239000004909 Moisturizer Substances 0.000 claims description 4
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 4
- 229960005274 benzocaine Drugs 0.000 claims description 4
- 229960000870 betamethasone benzoate Drugs 0.000 claims description 4
- SOQJPQZCPBDOMF-YCUXZELOSA-N betamethasone benzoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@@H]1C)C(=O)CO)C(=O)C1=CC=CC=C1 SOQJPQZCPBDOMF-YCUXZELOSA-N 0.000 claims description 4
- 229960004311 betamethasone valerate Drugs 0.000 claims description 4
- SNHRLVCMMWUAJD-SUYDQAKGSA-N betamethasone valerate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CCCC)[C@@]1(C)C[C@@H]2O SNHRLVCMMWUAJD-SUYDQAKGSA-N 0.000 claims description 4
- 229960005091 chloramphenicol Drugs 0.000 claims description 4
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 claims description 4
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 claims description 4
- 229960004475 chlortetracycline Drugs 0.000 claims description 4
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 claims description 4
- 235000019365 chlortetracycline Nutrition 0.000 claims description 4
- 229960001747 cinchocaine Drugs 0.000 claims description 4
- PUFQVTATUTYEAL-UHFFFAOYSA-N cinchocaine Chemical compound C1=CC=CC2=NC(OCCCC)=CC(C(=O)NCCN(CC)CC)=C21 PUFQVTATUTYEAL-UHFFFAOYSA-N 0.000 claims description 4
- 229960003662 desonide Drugs 0.000 claims description 4
- WBGKWQHBNHJJPZ-LECWWXJVSA-N desonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O WBGKWQHBNHJJPZ-LECWWXJVSA-N 0.000 claims description 4
- 229960002383 halcinonide Drugs 0.000 claims description 4
- 239000007943 implant Substances 0.000 claims description 4
- 229960004130 itraconazole Drugs 0.000 claims description 4
- 229960003377 metandienone Drugs 0.000 claims description 4
- 230000001333 moisturizer Effects 0.000 claims description 4
- 229940049954 penicillin Drugs 0.000 claims description 4
- 239000004100 Oxytetracycline Substances 0.000 claims description 3
- 229960004150 aciclovir Drugs 0.000 claims description 3
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 claims description 3
- 150000001450 anions Chemical class 0.000 claims description 3
- 238000010668 complexation reaction Methods 0.000 claims description 3
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical compound NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 claims description 3
- 229960001907 nitrofurazone Drugs 0.000 claims description 3
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- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 claims description 3
- 235000019366 oxytetracycline Nutrition 0.000 claims description 3
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- 230000000475 sunscreen effect Effects 0.000 claims description 3
- 239000000516 sunscreening agent Substances 0.000 claims description 3
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 claims description 3
- 230000002485 urinary effect Effects 0.000 claims description 3
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- 229960001347 fluocinolone acetonide Drugs 0.000 claims 2
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 2
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- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 30
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- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 12
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- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
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- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/43—Hormones, e.g. dexamethasone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne de manière générale des compositions antimicrobiennes à base d'argent et les procédés de fabrication desdites compositions. De manière particulière, la présente invention décrit des compositions antimicrobiennes stables et purifiées à base d'argent et des procédés de fabrication de telles compositions, comprenant des complexes ionisés de thiosulfate d'argent sans entraîneur soit en suspension dans une base, soit incorporées dans un support. Lesdites compositions antimicrobiennes de complexes ionisés de thiosulfate d'argent servent pour le traitement et la prévention de certaines maladies et infections.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002383742A CA2383742C (fr) | 1996-08-16 | 1997-08-15 | Compositions antimicrobiennes a base d'argent |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2410896P | 1996-08-16 | 1996-08-16 | |
| US60/024,108 | 1996-08-16 | ||
| US08/909,239 US6093414A (en) | 1997-08-11 | 1997-08-11 | Silver-based antimicrobial compositions |
| US08/909,239 | 1997-08-11 | ||
| PCT/US1997/014697 WO1998006260A1 (fr) | 1996-08-16 | 1997-08-15 | Compositions antimicrobiennes a base d'argent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002383742A Division CA2383742C (fr) | 1996-08-16 | 1997-08-15 | Compositions antimicrobiennes a base d'argent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2263473A1 CA2263473A1 (fr) | 1998-02-19 |
| CA2263473C true CA2263473C (fr) | 2003-04-22 |
Family
ID=26698050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002263473A Expired - Fee Related CA2263473C (fr) | 1996-08-16 | 1997-08-15 | Compositions antimicrobiennes a base d'argent |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0920252A4 (fr) |
| AU (1) | AU735373B2 (fr) |
| CA (1) | CA2263473C (fr) |
| WO (1) | WO1998006260A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011262362B2 (en) * | 2010-06-04 | 2014-06-05 | Smiths Medical Asd, Inc. | Antimicrobial lubricant |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7026308B1 (en) | 1999-06-25 | 2006-04-11 | The Procter & Gamble Company | Topical anti-microbial compositions |
| CN100341408C (zh) | 1999-06-25 | 2007-10-10 | 阿奇化工公司 | 用银、铜或锌离子增效的羟基吡啶硫酮抗微生物剂 |
| DE19956398A1 (de) * | 1999-11-24 | 2001-06-13 | Hahl Filaments Gmbh & Co Kg | Monofile Kunstfaser |
| IL133473A0 (en) * | 1999-12-12 | 2001-04-30 | Avenir R & B Medical Technolog | Bactericidal haemostatic preparations for local use and the methods of their production and conservation |
| EP1244476B1 (fr) | 1999-12-30 | 2006-05-31 | Acrymed | Procedes et compositions destines a des dispositifs d'administration ameliores |
| EP1343510B1 (fr) | 2000-11-29 | 2010-05-19 | ConvaTec Technologies Inc. | Substances anti-microbiennes stabilisees par rayonnement |
| RU2220982C9 (ru) * | 2001-01-05 | 2016-04-20 | Иркутский институт химии им. А.Е.Фаворского СО РАН, Государственное учреждение "Научный центр реконструктивной и восстановительной хирургии Восточно-Сибирского научного центра СО РАМН" | Аргакрил - новое антисептическое и гемостатическое средство |
| WO2003002164A2 (fr) * | 2001-06-29 | 2003-01-09 | Dow Global Technologies Inc. | Polymeres superabsorbants contenant un carboxyle et presentant des proprietes d'elimination des odeurs, et procede de preparation associe |
| WO2003002089A1 (fr) * | 2001-06-29 | 2003-01-09 | Dow Global Technologies Inc. | Polymeres superabsorbants a base de carboxyle presentant des proprietes desodorisantes et procede de fabrication associe |
| US7745686B2 (en) | 2001-11-02 | 2010-06-29 | Playtex Products, Inc. | Catamenial device |
| US9381382B2 (en) | 2002-06-04 | 2016-07-05 | The Procter & Gamble Company | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network |
| US9381148B2 (en) | 2003-03-18 | 2016-07-05 | The Procter & Gamble Company | Composition comprising particulate zinc material with a high relative zinc lability |
| NZ552928A (en) | 2004-07-30 | 2011-05-27 | Acrymed Inc | Antimicrobial silver compositions |
| CN102783499A (zh) | 2004-07-30 | 2012-11-21 | 金伯利-克拉克环球有限公司 | 抗微生物的装置和组合物 |
| US9289378B2 (en) | 2004-09-20 | 2016-03-22 | Avent, Inc. | Antimicrobial amorphous compositions |
| GB0525504D0 (en) | 2005-12-14 | 2006-01-25 | Bristol Myers Squibb Co | Antimicrobial composition |
| AU2008281278B2 (en) * | 2007-08-02 | 2012-08-09 | Covalon Technologies Ltd. | Antimicrobial photo-stable coating composition |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| CN102274135A (zh) * | 2011-08-25 | 2011-12-14 | 宁夏医科大学 | 防干裂唇膏 |
| US9006462B2 (en) | 2013-02-28 | 2015-04-14 | Dermira, Inc. | Glycopyrrolate salts |
| KR20150119468A (ko) | 2013-02-28 | 2015-10-23 | 더미라, 인코포레이티드 | 글리코피롤레이트 염 |
| GB201308770D0 (en) | 2013-05-15 | 2013-06-26 | Convatec Technologies Inc | Wound Dressing Comprising an Antimicrobial Composition |
| EP2944565B1 (fr) | 2014-05-13 | 2017-09-27 | Entrotech, Inc. | Manchon de protection contre l'érosion |
| PL411078A1 (pl) * | 2015-01-27 | 2016-08-01 | Uniwersytet Medyczny w Łodzi | Związek kompleksowy srebra, sposób wytwarzania związku kompleksowego oraz zastosowanie związku kompleksowego |
| US11944095B2 (en) | 2017-04-05 | 2024-04-02 | Suominen Corporation | Substrate for efficient use in sanitizing and disinfecting |
| CN112897472B (zh) * | 2021-02-03 | 2022-09-06 | 晋大纳米科技（厦门）有限公司 | 一种耐高温耐光照的络合银溶液的制备方法、络合银溶液及抗菌产品 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR882M (fr) * | 1961-01-18 | 1961-10-06 | ||
| US4581028A (en) * | 1984-04-30 | 1986-04-08 | The Trustees Of Columbia University In The City Of New York | Infection-resistant materials and method of making same through use of sulfonamides |
| US4677143A (en) * | 1984-10-01 | 1987-06-30 | Baxter Travenol Laboratories, Inc. | Antimicrobial compositions |
| US5102401A (en) * | 1990-08-22 | 1992-04-07 | Becton, Dickinson And Company | Expandable catheter having hydrophobic surface |
| JP2590653B2 (ja) * | 1990-11-28 | 1997-03-12 | 松下電器産業株式会社 | 抗菌性複合体、その製造法、それを用いた樹脂およびコ−キング材 |
| US5429819A (en) * | 1992-10-14 | 1995-07-04 | Matsushita Electric Industrial Co., Ltd. | Antiviral composition |
-
1997
- 1997-08-15 AU AU40797/97A patent/AU735373B2/en not_active Ceased
- 1997-08-15 CA CA002263473A patent/CA2263473C/fr not_active Expired - Fee Related
- 1997-08-15 WO PCT/US1997/014697 patent/WO1998006260A1/fr not_active Ceased
- 1997-08-15 EP EP97938487A patent/EP0920252A4/fr not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011262362B2 (en) * | 2010-06-04 | 2014-06-05 | Smiths Medical Asd, Inc. | Antimicrobial lubricant |
Also Published As
| Publication number | Publication date |
|---|---|
| AU735373B2 (en) | 2001-07-05 |
| WO1998006260A1 (fr) | 1998-02-19 |
| EP0920252A1 (fr) | 1999-06-09 |
| CA2263473A1 (fr) | 1998-02-19 |
| AU4079797A (en) | 1998-03-06 |
| EP0920252A4 (fr) | 2004-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |