CA2268751A1 - Proteines "fringe" et signalisation de notch - Google Patents
Proteines "fringe" et signalisation de notch Download PDFInfo
- Publication number
- CA2268751A1 CA2268751A1 CA002268751A CA2268751A CA2268751A1 CA 2268751 A1 CA2268751 A1 CA 2268751A1 CA 002268751 A CA002268751 A CA 002268751A CA 2268751 A CA2268751 A CA 2268751A CA 2268751 A1 CA2268751 A1 CA 2268751A1
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- CA
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- Prior art keywords
- fringe
- protein
- sequence
- mammalian
- notch
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
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- Wood Science & Technology (AREA)
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- Biochemistry (AREA)
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- Molecular Biology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
On a cloné et séquencé trois ADNc frangés de mammifère; on a décrit leur interaction avec la voie de signalisation du récepteur de Notch. L'invention propose des méthodes de prévention et de traitement de troubles caractérisés par une anomalie de signalisation du récepteur de Notch.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2839896P | 1996-10-21 | 1996-10-21 | |
| US60/028,398 | 1996-10-21 | ||
| PCT/CA1997/000775 WO1998017793A1 (fr) | 1996-10-21 | 1997-10-20 | Proteines 'fringe' et signalisation de notch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2268751A1 true CA2268751A1 (fr) | 1998-04-30 |
Family
ID=21843249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002268751A Abandoned CA2268751A1 (fr) | 1996-10-21 | 1997-10-20 | Proteines "fringe" et signalisation de notch |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0939814A1 (fr) |
| CA (1) | CA2268751A1 (fr) |
| WO (1) | WO1998017793A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0861261T3 (da) | 1995-06-28 | 2009-12-14 | Imp Cancer Res Tech | Nukleotid- og proteinsekvenser af hvirveldyrs-Delta-gener og fremgangsmåder baseret derpå |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| GB0019242D0 (en) * | 2000-08-04 | 2000-09-27 | Lorantis Ltd | Assay |
-
1997
- 1997-10-20 WO PCT/CA1997/000775 patent/WO1998017793A1/fr not_active Ceased
- 1997-10-20 EP EP97944671A patent/EP0939814A1/fr not_active Withdrawn
- 1997-10-20 CA CA002268751A patent/CA2268751A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0939814A1 (fr) | 1999-09-08 |
| WO1998017793A1 (fr) | 1998-04-30 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |