CA2270055A1 - Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes - Google Patents

Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes Download PDF

Info

Publication number
CA2270055A1
CA2270055A1 CA002270055A CA2270055A CA2270055A1 CA 2270055 A1 CA2270055 A1 CA 2270055A1 CA 002270055 A CA002270055 A CA 002270055A CA 2270055 A CA2270055 A CA 2270055A CA 2270055 A1 CA2270055 A1 CA 2270055A1
Authority
CA
Canada
Prior art keywords
phenyl
cis
hydroxy
chromane
phenylchromane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002270055A
Other languages
English (en)
Inventor
Paul Stanley Bury
Anders Kanstrup
Lise Brown Christiansen
Poul Jacobsen
Svend Treppendahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2270055A1 publication Critical patent/CA2270055A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des composés actifs sur le plan thérapeutique représentés par la formule (I) un procédé servant à préparer ces composés et des compositions pharmaceutiques contenant ces composés. Ces nouveaux composés sont utiles pour la prévention ou le traitement de maladies ou de syndromes relatifs aux oestrogènes.
CA002270055A 1996-10-28 1997-10-28 Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes Abandoned CA2270055A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK119896 1996-10-28
DK1198/96 1996-10-28
PCT/DK1997/000484 WO1998018777A1 (fr) 1996-10-28 1997-10-28 Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes

Publications (1)

Publication Number Publication Date
CA2270055A1 true CA2270055A1 (fr) 1998-05-07

Family

ID=8102077

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002270055A Abandoned CA2270055A1 (fr) 1996-10-28 1997-10-28 Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes

Country Status (8)

Country Link
EP (1) EP0937061A1 (fr)
JP (1) JP2001502709A (fr)
AU (1) AU4772197A (fr)
CA (1) CA2270055A1 (fr)
IL (1) IL129617A0 (fr)
NO (1) NO992004L (fr)
WO (1) WO1998018777A1 (fr)
ZA (1) ZA979648B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4913056B2 (ja) * 2004-09-21 2012-04-11 マーシャル エドワーズ，インコーポレーテッド 置換クロマン誘導体、医薬品、および治療における使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
HUP9702244A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for manufacture of a pharmaceutical composition for treatment or prophylaxis of gynaecological disorders

Also Published As

Publication number Publication date
ZA979648B (en) 1998-04-28
EP0937061A1 (fr) 1999-08-25
NO992004D0 (no) 1999-04-27
JP2001502709A (ja) 2001-02-27
WO1998018777A1 (fr) 1998-05-07
IL129617A0 (en) 2000-02-29
AU4772197A (en) 1998-05-22
NO992004L (no) 1999-06-25

Similar Documents

Publication Publication Date Title
EP0937060B1 (fr) Derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
US5985306A (en) (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes
US5994390A (en) Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5919817A (en) Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU744403B2 (en) Novel trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
EP0937062B1 (fr) Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
EP0937057B1 (fr) Nouveaux (-)-enantiomeres de derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes associes aux oestrogenes
CA2270056A1 (fr) Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
AU4700097A (en) Novel (cis)-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5958967A (en) Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
CA2269970A1 (fr) Nouveaux (+)-enantiomeres de derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
CA2270057A1 (fr) Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
CA2270055A1 (fr) Nouveaux derives de cis-3,4-chromane utiles pour la prevention ou le traitement de maladies ou de syndromes relatifs aux oestrogenes
US20010021710A1 (en) Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU9734501A (en) Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or sydndromes
AU9733801A (en) Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU9733501A (en) Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU9733601A (en) Novel (+)-enantiomers of cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU9733701A (en) Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related disease or sydnromes
AU9734001A (en) Novel (-)-enantiomers of cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued