CA2276087A1 - Plantes transgeniques dotees de voies modifiees de synthese biologique des sterols - Google Patents

Plantes transgeniques dotees de voies modifiees de synthese biologique des sterols Download PDF

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Publication number
CA2276087A1
CA2276087A1 CA002276087A CA2276087A CA2276087A1 CA 2276087 A1 CA2276087 A1 CA 2276087A1 CA 002276087 A CA002276087 A CA 002276087A CA 2276087 A CA2276087 A CA 2276087A CA 2276087 A1 CA2276087 A1 CA 2276087A1
Authority
CA
Canada
Prior art keywords
sterol
plant
delta
smt
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002276087A
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English (en)
Inventor
W. David Nes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2276087A1 publication Critical patent/CA2276087A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Cette invention se rapporte à la modulation des compositions de phytostérols dans des plantes transgéniques, qui permet de conférer à ces plantes une certaine résistance aux insectes, aux nématodes, aux champignons et/ou aux agressions exercées par l'environnement, et/ou d'accroître la valeur nutritionnelle de ces plantes. L'invention se rapporte à des molécules d'ADN recombinées qui codent l'ARN ou les séquences protéiques susceptibles de modifier les profils de stérols des plantes par modification de l'expression ou de l'activité d'enzymes assurant la synthèse biologique des stérols. Les molécules d'ADN sont transformées en cellules végétales et les plantes régénérées à partir de ces cellules possèdent des compositions de stérols modifiées.
CA002276087A 1996-12-26 1997-12-24 Plantes transgeniques dotees de voies modifiees de synthese biologique des sterols Abandoned CA2276087A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3392396P 1996-12-26 1996-12-26
US60/033,923 1996-12-26
PCT/US1997/023495 WO1998045457A1 (fr) 1996-12-26 1997-12-24 Plantes transgeniques dotees de voies modifiees de synthese biologique des sterols

Publications (1)

Publication Number Publication Date
CA2276087A1 true CA2276087A1 (fr) 1998-10-15

Family

ID=21873233

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002276087A Abandoned CA2276087A1 (fr) 1996-12-26 1997-12-24 Plantes transgeniques dotees de voies modifiees de synthese biologique des sterols

Country Status (6)

Country Link
EP (1) EP0958370A1 (fr)
CN (1) CN1247569A (fr)
AU (1) AU724046B2 (fr)
BR (1) BR9714439A (fr)
CA (1) CA2276087A1 (fr)
WO (1) WO1998045457A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008190A2 (fr) * 1998-08-03 2000-02-17 Arizona Board Of Regents On Behalf Of The University Of Arizona Gene de la methyltransferase des sterols
BR0010597A (pt) 1999-04-12 2002-02-13 Monsanto Technology Llc Plantas transgênicas contendo nìveis alterados de compostos esterol e tocoferóis
CA2381259A1 (fr) * 1999-09-30 2001-04-05 E. I. Du Pont De Nemours And Company Genes codant une sterol delta-14 reductase chez les plantes
GB9925453D0 (en) * 1999-10-27 1999-12-29 Univ Bristol Increasing isoprenoid biosynthesis
BR0014934A (pt) * 1999-10-27 2002-06-18 Unilever Nv Usos de um gene que expressa uma hmg-redutase sem retro-inibição e de um gene heterólogo que expressa uma hmg-redutase sem retro-inibição truncada, método de obtenção de sementes, planta, tecido de planta, sementes, método de obtenção de óleo, e, produto alimentìcio
BR0109953A (pt) * 2000-04-14 2003-05-27 Unilever Nv Semente de tabaco, canola, girassol, colza ou soja, uso de um gene que expressa um smt1, método para obter sementes, sementes, método de obtenção de óleo que compreende esteróis, produto alimentìcio, método para aumentar o nìvel de esteróis nas sementes de plantas e/ou diminuir o nìvel de colesterol em sementes de plantas
US20040019192A1 (en) * 2000-11-24 2004-01-29 Mark Harker Process for modifying plants
US6822142B2 (en) 2001-01-05 2004-11-23 Monsanto Company Transgenic plants containing altered levels of steroid compounds
DE10203352A1 (de) * 2002-01-29 2003-07-31 Basf Ag Verfahren zur Herstellung von 7-Dehydrocholesterol und/oder dessen biosynthetischen Zwischen- und/oder Folgeprodukten in transgenen Organismen
EP2216405A1 (fr) 2002-05-03 2010-08-11 Monsanto Technology LLC Promoteurs USP spécifiques de sémences pour l'expression de gènes dans des plantes
EP1521838A1 (fr) * 2002-07-16 2005-04-13 Unilever N.V. Procede de modification de vegetaux
WO2006092449A2 (fr) 2005-03-02 2006-09-08 Metanomics Gmbh Procede de production de produits chimiques fins
JP5174430B2 (ja) * 2007-11-06 2013-04-03 花王株式会社 ２−フェニルエチルアルコールの製造方法
EP2510090A1 (fr) * 2009-12-09 2012-10-17 BASF Plant Science Company GmbH Méthode d'augmentation de la résistance aux champignons de végétaux par silençage du gène smt1 des champignons
WO2012156902A1 (fr) * 2011-05-16 2012-11-22 Basf Plant Science Company Gmbh Plantes transgéniques résistantes aux nématodes
ES2842501T5 (es) 2015-09-21 2023-04-13 Modern Meadow Inc Materiales compuestos de tejido reforzados con fibras
US11525042B2 (en) 2016-02-15 2022-12-13 Modern Meadow, Inc. Composite biofabricated material
CA3008850A1 (fr) 2017-06-29 2018-12-29 Modern Meadow, Inc. Souches de levure et methode de production de collagene
AU2018253595A1 (en) 2017-11-13 2019-05-30 Modern Meadow, Inc. Biofabricated leather articles having zonal properties
EP3704202A4 (fr) 2019-01-17 2020-12-16 Modern Meadow, Inc. Matériaux de collagène en couches et leurs procédés de fabrication
EP4143258A4 (fr) 2020-05-01 2024-05-22 Modern Meadow, Inc. Alliages de protéine-polyuréthane et matériaux en couches comprenant ceux-ci
CN111500624B (zh) * 2020-06-30 2020-10-30 中国农业科学院生物技术研究所 CrSMT基因在提高植物对于生物胁迫以及非生物胁迫抗性中的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306862A (en) * 1990-10-12 1994-04-26 Amoco Corporation Method and composition for increasing sterol accumulation in higher plants
WO1997048793A1 (fr) * 1996-06-21 1997-12-24 The General Hospital Corporation Reductases de sterol de plantes et leurs utilisations

Also Published As

Publication number Publication date
AU724046B2 (en) 2000-09-07
WO1998045457A1 (fr) 1998-10-15
EP0958370A1 (fr) 1999-11-24
AU5709998A (en) 1998-10-30
CN1247569A (zh) 2000-03-15
BR9714439A (pt) 2000-03-21

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20031224