CA2276324A1 - La loratadine employee comme anti-arythmisant - Google Patents

La loratadine employee comme anti-arythmisant Download PDF

Info

Publication number: CA2276324A1
Authority: CA; Canada
Prior art keywords: loratadine; antiarrhythmic; descarboethoxycarbonyl; cyclohepta; ylidene
Prior art date: 1998-06-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA002276324A

Other languages

English (en)

Other versions

CA2276324C (fr

Inventor

Guy Buckland

Carol Ann Satler

Tilman Friedrich

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Products Inc

Original Assignee

Pfizer Products Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-30

Filing date

1999-06-28

Publication date

1999-12-30

1999-06-28 Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc

1999-12-30 Publication of CA2276324A1 publication Critical patent/CA2276324A1/fr

2003-08-19 Application granted granted Critical

2003-08-19 Publication of CA2276324C publication Critical patent/CA2276324C/fr

2019-06-28 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 title abstract 4
229960003088 loratadine Drugs 0.000 title abstract 3
230000003288 anthiarrhythmic effect Effects 0.000 title 1
239000003416 antiarrhythmic agent Substances 0.000 title 1
206010003658 Atrial Fibrillation Diseases 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
206010003119 arrhythmia Diseases 0.000 abstract 1
230000006793 arrhythmia Effects 0.000 abstract 1
-1 i. e. Chemical compound 0.000 abstract 1
239000002207 metabolite Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CA002276324A 1998-06-30 1999-06-28 La loratadine employee comme anti-arythmisant Expired - Fee Related CA2276324C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9124698P	1998-06-30	1998-06-30
US60/091,246		1998-06-30

Publications (2)

Publication Number	Publication Date
CA2276324A1 true CA2276324A1 (fr)	1999-12-30
CA2276324C CA2276324C (fr)	2003-08-19

Family

ID=22226786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002276324A Expired - Fee Related CA2276324C (fr)	1998-06-30	1999-06-28	La loratadine employee comme anti-arythmisant

Country Status (10)

Country	Link
US (1)	US6110927A (fr)
EP (1)	EP0968715B1 (fr)
JP (1)	JP2000034231A (fr)
AT (1)	ATE274907T1 (fr)
BR (1)	BR9902393A (fr)
CA (1)	CA2276324C (fr)
DE (1)	DE69919789T2 (fr)
DK (1)	DK0968715T3 (fr)
ES (1)	ES2226289T3 (fr)
PT (1)	PT968715E (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6555139B2 (en)	1999-06-28	2003-04-29	Wockhardt Europe Limited	Preparation of micron-size pharmaceutical particles by microfluidization
WO2002067938A2 (fr) *	2000-10-30	2002-09-06	Schering Corporation	Traitement médical
US6544557B2 (en)	2001-01-09	2003-04-08	Pan Pharmaceutical Limited	Effervescent tablet compositions
US6720002B2 (en)	2001-07-20	2004-04-13	R.P. Scherer Technologies, Inc.	Antihistamine formulations for soft capsule dosage forms
CA2690490C (fr)	2010-01-19	2012-06-26	Accucaps Industries Limited	Formulations pharmaceutiques de loratadine pour encapsulation et combinaisons associees

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1548022A (en) *	1976-10-06	1979-07-04	Wyeth John & Brother Ltd	Pharmaceutial dosage forms
US4282233B1 (en) *	1980-06-19	2000-09-05	Schering Corp	Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
JPS61501205A (ja) *	1984-02-15	1986-06-19	シェリング・コ−ポレ−ション	８↓−クロル↓−６，１１↓−ジヒドロ↓−１１↓−（４↓−ピペリジリデン）↓−５Ｈ↓−ベンゾ〔５，６〕シクロヘプタ〔１，２−ｂ〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物
US5595997A (en) *	1994-12-30	1997-01-21	Sepracor Inc.	Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine

1999
- 1999-06-04 PT PT99304375T patent/PT968715E/pt unknown
- 1999-06-04 DK DK99304375T patent/DK0968715T3/da active
- 1999-06-04 EP EP99304375A patent/EP0968715B1/fr not_active Expired - Lifetime
- 1999-06-04 DE DE69919789T patent/DE69919789T2/de not_active Expired - Fee Related
- 1999-06-04 ES ES99304375T patent/ES2226289T3/es not_active Expired - Lifetime
- 1999-06-04 AT AT99304375T patent/ATE274907T1/de not_active IP Right Cessation
- 1999-06-28 US US09/342,007 patent/US6110927A/en not_active Expired - Fee Related
- 1999-06-28 BR BR9902393-8A patent/BR9902393A/pt not_active IP Right Cessation
- 1999-06-28 CA CA002276324A patent/CA2276324C/fr not_active Expired - Fee Related
- 1999-06-29 JP JP11182656A patent/JP2000034231A/ja active Pending

Also Published As

Publication number	Publication date
ATE274907T1 (de)	2004-09-15
DE69919789D1 (de)	2004-10-07
ES2226289T3 (es)	2005-03-16
PT968715E (pt)	2004-12-31
BR9902393A (pt)	2000-05-02
US6110927A (en)	2000-08-29
DE69919789T2 (de)	2005-09-08
JP2000034231A (ja)	2000-02-02
EP0968715A1 (fr)	2000-01-05
DK0968715T3 (da)	2004-12-27
EP0968715B1 (fr)	2004-09-01
CA2276324C (fr)	2003-08-19

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Legal Events

Date	Code	Title	Description
1999-06-28	EEER	Examination request
2006-06-28	MKLA	Lapsed