CA2279608C - Reservoir pour materiau sensible a l'humidite - Google Patents

Reservoir pour materiau sensible a l'humidite Download PDF

Info

Publication number: CA2279608C
Authority: CA; Canada
Prior art keywords: desiccating; formulation according; closure; polymer; desiccant
Prior art date: 1994-08-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA002279608A

Other languages

English (en)

Other versions

CA2279608A1 (fr

Inventor

Charles Bernard Taskis

Simon Joseph Holland

Paul John Whatmore

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

West Pharmaceutical Services Cornwall Ltd

Original Assignee

West Pharmaceutical Services Cornwall Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-05

Filing date

1995-08-04

Publication date

2000-09-05

1994-08-05 Priority claimed from GB9415864A external-priority patent/GB9415864D0/en

1995-06-16 Priority claimed from GBGB9512243.8A external-priority patent/GB9512243D0/en

1995-08-04 Application filed by West Pharmaceutical Services Cornwall Ltd filed Critical West Pharmaceutical Services Cornwall Ltd

1995-08-04 Priority claimed from CA002196673A external-priority patent/CA2196673C/fr

1996-02-15 Publication of CA2279608A1 publication Critical patent/CA2279608A1/fr

2000-09-05 Application granted granted Critical

2000-09-05 Publication of CA2279608C publication Critical patent/CA2279608C/fr

2015-08-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

239000000463 material Substances 0.000 title claims abstract description 81
229920000642 polymer Polymers 0.000 claims abstract description 81
229920001971 elastomer Polymers 0.000 claims description 39
239000005060 rubber Substances 0.000 claims description 38
239000000203 mixture Substances 0.000 claims description 34
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 30
238000009472 formulation Methods 0.000 claims description 25
ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 claims description 25
239000013536 elastomeric material Substances 0.000 claims description 23
LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 claims description 22
229960003022 amoxicillin Drugs 0.000 claims description 22
LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 claims description 22
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 21
229910052708 sodium Inorganic materials 0.000 claims description 21
239000011734 sodium Substances 0.000 claims description 21
239000000945 filler Substances 0.000 claims description 19
239000002808 molecular sieve Substances 0.000 claims description 17
URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 claims description 17
238000000034 method Methods 0.000 claims description 14
BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 11
239000000292 calcium oxide Substances 0.000 claims description 11
ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 11
238000003860 storage Methods 0.000 claims description 9
239000011521 glass Substances 0.000 claims description 8
NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 8
238000004891 communication Methods 0.000 claims description 6
229920005555 halobutyl Polymers 0.000 claims description 6
125000004968 halobutyl group Chemical group 0.000 claims description 6
238000000354 decomposition reaction Methods 0.000 claims description 5
229920005556 chlorobutyl Polymers 0.000 claims description 4
239000007972 injectable composition Substances 0.000 claims description 3
229920002379 silicone rubber Polymers 0.000 claims description 3
239000008194 pharmaceutical composition Substances 0.000 claims description 2
239000004945 silicone rubber Substances 0.000 claims description 2
239000002274 desiccant Substances 0.000 abstract description 110
239000007787 solid Substances 0.000 abstract description 5
229920001577 copolymer Polymers 0.000 description 20
239000000126 substance Substances 0.000 description 16
238000010276 construction Methods 0.000 description 12
239000000017 hydrogel Substances 0.000 description 11
WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 9
238000007906 compression Methods 0.000 description 9
230000006835 compression Effects 0.000 description 9
239000004033 plastic Substances 0.000 description 8
229920003023 plastic Polymers 0.000 description 8
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 7
229910052700 potassium Inorganic materials 0.000 description 7
239000011591 potassium Substances 0.000 description 7
238000001035 drying Methods 0.000 description 6
-1 hydroxy alkyl methacrylates Chemical class 0.000 description 6
229910052751 metal Inorganic materials 0.000 description 6
239000002184 metal Substances 0.000 description 6
230000008569 process Effects 0.000 description 6
230000000717 retained effect Effects 0.000 description 6
239000000243 solution Substances 0.000 description 6
229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 description 4
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
230000000694 effects Effects 0.000 description 4
229920001477 hydrophilic polymer Polymers 0.000 description 4
239000011256 inorganic filler Substances 0.000 description 4
229910003475 inorganic filler Inorganic materials 0.000 description 4
239000012763 reinforcing filler Substances 0.000 description 4
WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical class C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 3
230000009471 action Effects 0.000 description 3
239000012736 aqueous medium Substances 0.000 description 3
239000002585 base Substances 0.000 description 3
238000013329 compounding Methods 0.000 description 3
238000004090 dissolution Methods 0.000 description 3
239000003814 drug Substances 0.000 description 3
238000002474 experimental method Methods 0.000 description 3
230000036571 hydration Effects 0.000 description 3
238000006703 hydration reaction Methods 0.000 description 3
230000007062 hydrolysis Effects 0.000 description 3
238000006460 hydrolysis reaction Methods 0.000 description 3
238000011065 in-situ storage Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000002245 particle Substances 0.000 description 3
239000000047 product Substances 0.000 description 3
238000007789 sealing Methods 0.000 description 3
229920003051 synthetic elastomer Polymers 0.000 description 3
239000005061 synthetic rubber Substances 0.000 description 3
KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
238000010521 absorption reaction Methods 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000004913 activation Effects 0.000 description 2
230000008901 benefit Effects 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
239000002775 capsule Substances 0.000 description 2
238000011109 contamination Methods 0.000 description 2
238000009826 distribution Methods 0.000 description 2
STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Chemical compound CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 description 2
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
238000002347 injection Methods 0.000 description 2
239000007924 injection Substances 0.000 description 2
239000007788 liquid Substances 0.000 description 2
230000007774 longterm Effects 0.000 description 2
238000005259 measurement Methods 0.000 description 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
229920003052 natural elastomer Polymers 0.000 description 2
229920001194 natural rubber Polymers 0.000 description 2
239000006187 pill Substances 0.000 description 2
229920000728 polyester Polymers 0.000 description 2
229920003048 styrene butadiene rubber Polymers 0.000 description 2
239000003826 tablet Substances 0.000 description 2
238000012360 testing method Methods 0.000 description 2
238000005406 washing Methods 0.000 description 2
OLQFXOWPTQTLDP-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCO OLQFXOWPTQTLDP-UHFFFAOYSA-N 0.000 description 1
MCWMYICYUGCRDY-UHFFFAOYSA-N 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOCCOCCO MCWMYICYUGCRDY-UHFFFAOYSA-N 0.000 description 1
OELQSSWXRGADDE-UHFFFAOYSA-N 2-methylprop-2-eneperoxoic acid Chemical compound CC(=C)C(=O)OO OELQSSWXRGADDE-UHFFFAOYSA-N 0.000 description 1
DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 description 1
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
239000004150 EU approved colour Substances 0.000 description 1
BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
229920000181 Ethylene propylene rubber Polymers 0.000 description 1
244000043261 Hevea brasiliensis Species 0.000 description 1
CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
239000004698 Polyethylene Substances 0.000 description 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
239000002174 Styrene-butadiene Substances 0.000 description 1
XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
239000002250 absorbent Substances 0.000 description 1
239000000654 additive Substances 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
230000001070 adhesive effect Effects 0.000 description 1
150000001447 alkali salts Chemical class 0.000 description 1
239000003963 antioxidant agent Substances 0.000 description 1
239000003782 beta lactam antibiotic agent Substances 0.000 description 1
239000003781 beta lactamase inhibitor Substances 0.000 description 1
229940126813 beta-lactamase inhibitor Drugs 0.000 description 1
MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 description 1
229920005549 butyl rubber Polymers 0.000 description 1
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
239000000920 calcium hydroxide Substances 0.000 description 1
229910001861 calcium hydroxide Inorganic materials 0.000 description 1
210000000845 cartilage Anatomy 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
229920003193 cis-1,4-polybutadiene polymer Polymers 0.000 description 1
239000011247 coating layer Substances 0.000 description 1
239000002131 composite material Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
OIWOHHBRDFKZNC-UHFFFAOYSA-N cyclohexyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC1CCCCC1 OIWOHHBRDFKZNC-UHFFFAOYSA-N 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
230000018044 dehydration Effects 0.000 description 1
238000006297 dehydration reaction Methods 0.000 description 1
230000002939 deleterious effect Effects 0.000 description 1
239000000806 elastomer Substances 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
UIWXSTHGICQLQT-UHFFFAOYSA-N ethenyl propanoate Chemical compound CCC(=O)OC=C UIWXSTHGICQLQT-UHFFFAOYSA-N 0.000 description 1
239000002657 fibrous material Substances 0.000 description 1
230000004927 fusion Effects 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
239000007943 implant Substances 0.000 description 1
238000003780 insertion Methods 0.000 description 1
230000037431 insertion Effects 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
239000010410 layer Substances 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
238000000465 moulding Methods 0.000 description 1
229940088644 n,n-dimethylacrylamide Drugs 0.000 description 1
125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 description 1
230000035699 permeability Effects 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
229940127557 pharmaceutical product Drugs 0.000 description 1
229920002587 poly(1,3-butadiene) polymer Polymers 0.000 description 1
229920001084 poly(chloroprene) Polymers 0.000 description 1
229920000573 polyethylene Polymers 0.000 description 1
229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
229920001195 polyisoprene Polymers 0.000 description 1
239000002861 polymer material Substances 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
239000012858 resilient material Substances 0.000 description 1
230000000452 restraining effect Effects 0.000 description 1
238000010058 rubber compounding Methods 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000012216 screening Methods 0.000 description 1
239000000741 silica gel Substances 0.000 description 1
229910002027 silica gel Inorganic materials 0.000 description 1
239000012265 solid product Substances 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
125000006850 spacer group Chemical group 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
239000008223 sterile water Substances 0.000 description 1
239000011115 styrene butadiene Substances 0.000 description 1
230000004580 weight loss Effects 0.000 description 1
239000011787 zinc oxide Substances 0.000 description 1
239000002132 β-lactam antibiotic Substances 0.000 description 1
229940124586 β-lactam antibiotics Drugs 0.000 description 1
229940126085 β‑Lactamase Inhibitor Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
- B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Mechanical Engineering (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Food Science & Technology (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Packages (AREA)

CA002279608A 1994-08-05 1995-08-04 Reservoir pour materiau sensible a l'humidite Expired - Fee Related CA2279608C (fr)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
GB9415864A GB9415864D0 (en)	1994-08-05	1994-08-05	Container
GB9415864.9		1994-08-05
GBGB9512243.8A GB9512243D0 (en)	1995-06-16	1995-06-16	Container and closure
GB9512243.8		1995-06-16
CA002196673A CA2196673C (fr)	1994-08-05	1995-08-04	Reservoir pour materiau sensible a l'humidite

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002196673A Division CA2196673C (fr)	1994-08-05	1995-08-04	Reservoir pour materiau sensible a l'humidite

Publications (2)

Publication Number	Publication Date
CA2279608A1 CA2279608A1 (fr)	1996-02-15
CA2279608C true CA2279608C (fr)	2000-09-05

Family

ID=31191502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002279608A Expired - Fee Related CA2279608C (fr)	1994-08-05	1995-08-04	Reservoir pour materiau sensible a l'humidite

Country Status (1)

Country	Link
CA (1)	CA2279608C (fr)

1995
- 1995-08-04 CA CA002279608A patent/CA2279608C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2279608A1 (fr)	1996-02-15

Legal Events

Date	Code	Title	Description
1999-08-26	EEER	Examination request
2006-08-04	MKLA	Lapsed

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CA2337604C (fr)	2007-12-11	Polymeres modifies a vitesses de transmission regulees
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AU694548C (en)	2001-01-11	Container for moisture-sensitive material
AU711609B2 (en)	1999-10-14	Container for moisture-sensitive material
WO2000012088A1 (fr)	2000-03-09	Formulation pharmaceutique d'amoxycilline de sodium et de clavulanate de potassium
HK1023545A (en)	2000-09-15	Container for moisture-sensitive material
HK1024455A (en)	2000-10-13	Container for moisture-sensitive material