CA2281758A1 - Reparation d'anomalies des tissus autologues - Google Patents
Reparation d'anomalies des tissus autologues Download PDFInfo
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- CA2281758A1 CA2281758A1 CA002281758A CA2281758A CA2281758A1 CA 2281758 A1 CA2281758 A1 CA 2281758A1 CA 002281758 A CA002281758 A CA 002281758A CA 2281758 A CA2281758 A CA 2281758A CA 2281758 A1 CA2281758 A1 CA 2281758A1
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présent invention concerne une méthodologie d'augmentation à long terme et/ou de réparation de tissus cutanés, sous-cutanés ou des cordes vocales, par injection ou implantation chirurgicale directe de fibroblastes cultivés autologues provenant d'un tissu conjonctif, ou dermique, ou aponévrotique, ou de fibroblastes provenant de tissus du chorion de l'intestin ou d'adipocytes. Les fibroblastes cultivés utilisés pour l'augmentation et/ou la réparation d'anomalies cutanées proviennent d'un tissu conjonctif, et/ou dermique et/ou aponévrotique. L'invention concerne en outre une méthodologie qui permet de cultiver des cellules sensiblement débarrassées des protéines potentiellement immunogènes contenues dans le sérum en faisant passer, au stade final de leur culture, les fibroblastes issus de tissus du chorion de l'intestin ou d'adipocytes dans un milieu exempt de sérum, ou encore dans le propre sérum du patient.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3796197P | 1997-02-20 | 1997-02-20 | |
| US60/037,961 | 1997-02-20 | ||
| US09/003,328 US6081275A (en) | 1997-01-10 | 1998-01-06 | Image compositing apparatus |
| US09/003,378 | 1998-01-06 | ||
| PCT/US1998/003439 WO1998040027A1 (fr) | 1997-02-20 | 1998-02-20 | Augmentation ou reparation d'anomalies des tissus cutanes, sous-cutanes ou des cordes vocales |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2281758A1 true CA2281758A1 (fr) | 1998-09-17 |
| CA2281758C CA2281758C (fr) | 2014-09-23 |
Family
ID=26671627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2281758A Expired - Lifetime CA2281758C (fr) | 1997-02-20 | 1998-02-20 | Reparation d'anomalies des tissus autologues |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1014880A4 (fr) |
| JP (1) | JP2001509064A (fr) |
| AU (1) | AU740113B2 (fr) |
| BR (1) | BR9815713A (fr) |
| CA (1) | CA2281758C (fr) |
| WO (1) | WO1998040027A1 (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5591444A (en) * | 1995-07-28 | 1997-01-07 | Isolagen Technologies, Inc. | Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects |
| US7767452B2 (en) | 1997-02-20 | 2010-08-03 | Kleinsek Don A | Tissue treatments with adipocyte cells |
| GB2360948B (en) * | 1998-12-01 | 2003-12-10 | Purdue Research Foundation | Composition suitable for vocal cord reconstruction |
| US6918396B1 (en) | 1998-12-01 | 2005-07-19 | Purdue Research Foundation | Method for vocal cord reconstruction |
| JP2003517858A (ja) * | 1999-11-05 | 2003-06-03 | ジェリジーン メディカル コーポレーション | 老齢関連の軟組織の欠陥の増強と修復 |
| US8394371B2 (en) | 2002-02-11 | 2013-03-12 | Neocutis Sa | Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same |
| WO2004017972A1 (fr) * | 2002-08-23 | 2004-03-04 | Law Peter K | Reparation et amelioration biologique de la peau |
| MX343796B (es) * | 2003-03-13 | 2016-11-23 | M Burgess Cheryl | Metodos para administrar un material en un paciente para realce dermico. |
| US20060058238A1 (en) | 2004-09-15 | 2006-03-16 | Lee Laurent-Applegate | Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same |
| CA2626460A1 (fr) * | 2005-10-18 | 2007-04-26 | Organogenesis, Inc. | Constructions collageniques antimicrobiennes |
| GB2440908A (en) * | 2006-05-25 | 2008-02-20 | Intercytex Ltd | Tissue Repair and Augmentation |
| US20080306610A1 (en) * | 2007-06-07 | 2008-12-11 | Zimmer Orthobiologics, Inc. | Tissue processing for nonimmunogenic implants |
| US8455459B2 (en) | 2007-08-02 | 2013-06-04 | Medicis Pharmaceutical Corporation | Method of applying an injectable filler |
| RU2428996C2 (ru) * | 2009-08-28 | 2011-09-20 | Вадим Леонидович Зорин | Биотрансплантат для коррекции дефектов мягких тканей (варианты), способ получения биотрансплантата (варианты) и способ коррекции дефектов мягких тканей |
| US9113916B2 (en) | 2010-08-31 | 2015-08-25 | Zimmer, Inc. | Drill bit for osteochondral drilling with guiding element and uses thereof |
| US9370469B2 (en) * | 2014-03-14 | 2016-06-21 | Suneva Medical, Inc | Injectable alloplastic implants and methods of use thereof |
| FR3083246B1 (fr) * | 2018-06-29 | 2023-12-08 | Oreal | Modeles cellulaires et tissulaires comprenant des fibroblastes de la jonction dermo-hypodermique et ses applications |
| CN111117952A (zh) * | 2019-10-29 | 2020-05-08 | 济南磐升生物技术有限公司 | 一种修复妊娠纹的细胞混悬液及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0282746A1 (fr) * | 1987-02-19 | 1988-09-21 | Takeda Chemical Industries, Ltd. | Procédé de préparation de tissu cultivé de manière artificielle |
| GB8708009D0 (en) * | 1987-04-03 | 1987-05-07 | Clayton Found Res | Injectable soft tissue augmentation materials |
| US4837379A (en) * | 1988-06-02 | 1989-06-06 | Organogenesis Inc. | Fibrin-collagen tissue equivalents and methods for preparation thereof |
| US5374515A (en) * | 1992-11-13 | 1994-12-20 | Organogenesis, Inc. | In vitro cornea equivalent model |
| US5827641A (en) * | 1992-11-13 | 1998-10-27 | Parenteau; Nancy L. | In vitro cornea equivalent model |
| US5591444A (en) * | 1995-07-28 | 1997-01-07 | Isolagen Technologies, Inc. | Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects |
| IT1282207B1 (it) * | 1995-11-20 | 1998-03-16 | Fidia Advanced Biopolymers Srl | Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico |
| WO1998033889A1 (fr) * | 1997-01-31 | 1998-08-06 | The Penn State Research Foundation | Culture d'adipocytes |
-
1998
- 1998-02-20 WO PCT/US1998/003439 patent/WO1998040027A1/fr not_active Ceased
- 1998-02-20 BR BR9815713-2A patent/BR9815713A/pt not_active Application Discontinuation
- 1998-02-20 AU AU63344/98A patent/AU740113B2/en not_active Ceased
- 1998-02-20 JP JP53957898A patent/JP2001509064A/ja active Pending
- 1998-02-20 CA CA2281758A patent/CA2281758C/fr not_active Expired - Lifetime
- 1998-02-20 EP EP98907575A patent/EP1014880A4/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU740113B2 (en) | 2001-11-01 |
| BR9815713A (pt) | 2002-11-05 |
| JP2001509064A (ja) | 2001-07-10 |
| CA2281758C (fr) | 2014-09-23 |
| AU6334498A (en) | 1998-09-29 |
| WO1998040027A1 (fr) | 1998-09-17 |
| EP1014880A1 (fr) | 2000-07-05 |
| EP1014880A4 (fr) | 2000-08-16 |
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