CA2287254A1 - Cytokines de mammifere; reactifs et procedes connexes - Google Patents

Cytokines de mammifere; reactifs et procedes connexes Download PDF

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Publication number
CA2287254A1
CA2287254A1 CA002287254A CA2287254A CA2287254A1 CA 2287254 A1 CA2287254 A1 CA 2287254A1 CA 002287254 A CA002287254 A CA 002287254A CA 2287254 A CA2287254 A CA 2287254A CA 2287254 A1 CA2287254 A1 CA 2287254A1
Authority
CA
Canada
Prior art keywords
protein
seq
polypeptide
antibody
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002287254A
Other languages
English (en)
Inventor
Joseph A. Hedrick
Theodore R. Sana
J. Fernando Bazan
Robert A. Kastelein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2287254A1 publication Critical patent/CA2287254A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des acides nucléiques codant chez un mammifère (par exemple, rongeur) les protéines suivantes : IL-1.delta., IL-1.epsilon., IL-1.delta. et IL-1.epsilon. purifiées ainsi que des fragments de ces protéines. L'invention concerne aussi des anticorps polyclonaux et monoclonaux, et des procédés liés à l'utilisation des compositions considérées à des fins diagnostiques et thérapeutiques.
CA002287254A 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes Abandoned CA2287254A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US83762797A 1997-04-21 1997-04-21
US08/837,627 1997-04-21
US5511197P 1997-08-06 1997-08-06
US60/055,111 1997-08-06
PCT/US1998/006879 WO1998047921A1 (fr) 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes

Publications (1)

Publication Number Publication Date
CA2287254A1 true CA2287254A1 (fr) 1998-10-29

Family

ID=26733854

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002287254A Abandoned CA2287254A1 (fr) 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes

Country Status (5)

Country Link
EP (1) EP0977779A1 (fr)
JP (1) JP2002501496A (fr)
AU (1) AU7103198A (fr)
CA (1) CA2287254A1 (fr)
WO (1) WO1998047921A1 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000039297A2 (fr) * 1998-12-23 2000-07-06 Genentech, Inc. Polypeptides apparentes a il-1
US6197551B1 (en) * 1998-01-27 2001-03-06 Millennium Pharmaceuticals, Inc. Spoil-1 protein and nucleic acid molecules and uses therefor
EP1044271A1 (fr) 1998-01-09 2000-10-18 Immunex Corporation Adn codant il-1 delta et polypeptides il-1 delta
US6962904B1 (en) 1998-03-13 2005-11-08 Connective Tissue Imagineering Elastin peptide analogs and uses thereof
US6426191B1 (en) * 1998-04-03 2002-07-30 Hyseq, Inc. Assays involving an IL-1 receptor antagonist
US6541623B1 (en) 1998-04-03 2003-04-01 Hyseq, Inc. Interleukin—1 receptor antagonist and uses thereof
US6337072B1 (en) 1998-04-03 2002-01-08 Hyseq, Inc. Interleukin-1 receptor antagonist and recombinant production thereof
WO1999051744A2 (fr) * 1998-04-03 1999-10-14 Hyseq, Inc. Antagoniste du recepteur de l'interleukine-1 et ses utilisations
US6294655B1 (en) 1998-04-03 2001-09-25 Hyseq, Inc. Anti-interleukin-1 receptor antagonist antibodies and uses thereof
AU5772299A (en) * 1998-08-07 2000-02-28 Millennium Pharmaceuticals, Inc. Novel molecules of the tango-93-related protein family and uses thereof
US6838290B2 (en) 1998-08-21 2005-01-04 Immunex Corporation Methods for screening compounds that affect IL-1 epsilon activity
CA2340790C (fr) * 1998-08-21 2012-07-10 Immunex Corporation Adn humain il-1 epsilon et polypeptides
US6949359B1 (en) 1998-08-21 2005-09-27 Immunex Corporation Human IL-1 epsilon DNA and polypeptides
WO2000020595A1 (fr) * 1998-10-08 2000-04-13 Zymogenetics, Inc. Homologues de l'interleukine-1
US7074556B2 (en) 1999-03-02 2006-07-11 Invitrogen Corporation cDNA synthesis improvements
US6339141B1 (en) 1999-05-20 2002-01-15 Hycey Inc. Interleukin-1 Hy2 materials and methods
AU5282600A (en) 1999-05-20 2000-12-12 Hyseq, Inc. Interleukin-1 hy2 materials and methods
WO2000071583A1 (fr) * 1999-05-24 2000-11-30 Smithkline Beecham Corporation Homologue de l'interleukine 1 murine, il-1h3
EP1190097A2 (fr) 1999-06-22 2002-03-27 Invitrogen Corporation Amorces et procedes ameliores destines a la detection et a la discrimination d'acides nucleiques
US6830902B1 (en) 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
CA2378954A1 (fr) * 1999-07-16 2001-01-25 Interleukin Genetics, Inc. Gene il-1l1 et produits polypeptidiques
CA2393532A1 (fr) * 1999-12-10 2001-06-14 Frank J. Calzone Molecules de type antagoniste du recepteur d'interleukine-1 et utilisations
AU2001275018B2 (en) * 2000-05-30 2008-04-03 Connective Tissue Imagineering Llc Composition and method for enhancing elasticity of tissue
US6794362B1 (en) * 2000-05-30 2004-09-21 Connective Tissue Imagineering Llc Asparagine containing elastin peptide analogs
US20030165859A1 (en) 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
DK1899378T3 (da) * 2005-06-21 2010-02-01 Xoma Technology Ltd IL-1 beta-bindende antistoffer og fragmenter deraf
CN103221422B (zh) * 2010-07-29 2017-03-29 十一生物治疗股份有限公司 嵌合il‑1受体i型激动剂和拮抗剂
WO2012024642A1 (fr) 2010-08-20 2012-02-23 Life Technologies Corporation Dosage d'amplification en chaîne par polymérase en temps réel utilisant des amorces à double marquage de transfert d'énergie par résonance de fluorescence
WO2012103240A2 (fr) * 2011-01-25 2012-08-02 Eleven Biotherapeutics, Inc. Agents de liaison à un récepteur
WO2014071322A1 (fr) 2012-11-02 2014-05-08 Life Technologies Corporation Capture, détection et quantification de petit arn
US11254977B2 (en) 2013-03-12 2022-02-22 Life Technologies Corporation Universal reporter-based genotyping methods and materials
SG10201707477SA (en) 2013-03-13 2017-10-30 Eleven Biotherapeutics Inc Chimeric cytokine formulations for ocular delivery
PT3319985T (pt) 2015-07-06 2021-01-06 Immatics Biotechnologies Gmbh Novos péptidos e combinação de péptidos para uso em imunoterapia do cancro do esófago e outros cancros
GB201511792D0 (en) * 2015-07-06 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers
EP3472349A1 (fr) 2016-06-16 2019-04-24 Life Technologies Corporation Nouvelles compositions, procédés et kits permettant de détecter des micro-organismes
CN118207299A (zh) 2016-08-26 2024-06-18 生命技术公司 核酸提取和扩增对照及其使用方法
CN111527216A (zh) 2017-11-13 2020-08-11 生命技术公司 用于尿路微生物检测的组合物、方法和试剂盒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148009B1 (ko) * 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제

Also Published As

Publication number Publication date
EP0977779A1 (fr) 2000-02-09
AU7103198A (en) 1998-11-13
JP2002501496A (ja) 2002-01-15
WO1998047921A1 (fr) 1998-10-29
WO1998047921A9 (fr) 1999-04-22

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued