CA2288307C - Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence - Google Patents

Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence Download PDF

Info

Publication number
CA2288307C
CA2288307C CA2288307A CA2288307A CA2288307C CA 2288307 C CA2288307 C CA 2288307C CA 2288307 A CA2288307 A CA 2288307A CA 2288307 A CA2288307 A CA 2288307A CA 2288307 C CA2288307 C CA 2288307C
Authority
CA
Canada
Prior art keywords
cells
cell
isolated
nkp30
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2288307A
Other languages
English (en)
Other versions
CA2288307A1 (fr
Inventor
Alessandro Moretta
Cristina Bottino
Roberto Biassoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innate Pharma SA
DIMES Dipartimento di Medicina Sperimentale Universita degli Studi di Genova
Original Assignee
Innate Pharma SA
DIMES Dipartimento di Medicina Sperimentale Universita degli Studi di Genova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA2288307A priority Critical patent/CA2288307C/fr
Application filed by Innate Pharma SA, DIMES Dipartimento di Medicina Sperimentale Universita degli Studi di Genova filed Critical Innate Pharma SA
Priority to AU26677/01A priority patent/AU783899B2/en
Priority to AT00989877T priority patent/ATE423848T1/de
Priority to JP2001538509A priority patent/JP4776845B2/ja
Priority to PCT/EP2000/011697 priority patent/WO2001036630A2/fr
Priority to DE60041655T priority patent/DE60041655D1/de
Priority to DK00989877T priority patent/DK1240326T3/da
Priority to ES00989877T priority patent/ES2321687T3/es
Priority to EP00989877A priority patent/EP1240326B1/fr
Publication of CA2288307A1 publication Critical patent/CA2288307A1/fr
Application granted granted Critical
Publication of CA2288307C publication Critical patent/CA2288307C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2288307A 1999-11-15 1999-11-15 Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence Expired - Fee Related CA2288307C (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA2288307A CA2288307C (fr) 1999-11-15 1999-11-15 Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence
AT00989877T ATE423848T1 (de) 1999-11-15 2000-11-15 Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizieren
JP2001538509A JP4776845B2 (ja) 1999-11-15 2000-11-15 ヒトナチュラルキラー細胞によって媒介される天然細胞毒性に関連した新規トリガリングレセプターおよび同一の性質を有する抗体
PCT/EP2000/011697 WO2001036630A2 (fr) 1999-11-15 2000-11-15 Nouveau recepteur de declenchement implique dans la cytotoxicite naturelle induite par les lymphocytes tueurs naturels (nk) et anticorps permettant de l'identifier
AU26677/01A AU783899B2 (en) 1999-11-15 2000-11-15 Novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells, and antibodies that identify the same
DE60041655T DE60041655D1 (de) 1999-11-15 2000-11-15 Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizieren
DK00989877T DK1240326T3 (da) 1999-11-15 2000-11-15 Udlösende receptor der er involveret i naturlig cytotoxicitet medieret af humane naturlige dræberceller og antistoffer som identificerer denne receptor
ES00989877T ES2321687T3 (es) 1999-11-15 2000-11-15 Receptor activador implicado en la citotoxicidad natural mediada por las celulas destructoras naturales humanas y anticuerpos que identifican dicho receptor.
EP00989877A EP1240326B1 (fr) 1999-11-15 2000-11-15 Recepteur de declenchement implique dans la cytotoxicite naturelle induite par les lymphocytes tueurs naturels (natural killer cells) d'origine humaine et anticorps permettant d'identifier ce recepteur

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2288307A CA2288307C (fr) 1999-11-15 1999-11-15 Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence

Publications (2)

Publication Number Publication Date
CA2288307A1 CA2288307A1 (fr) 2001-05-15
CA2288307C true CA2288307C (fr) 2012-05-15

Family

ID=4164540

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2288307A Expired - Fee Related CA2288307C (fr) 1999-11-15 1999-11-15 Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence

Country Status (1)

Country Link
CA (1) CA2288307C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115925933A (zh) * 2015-12-28 2023-04-07 依奈特制药公司 NKp46结合蛋白的可变区

Also Published As

Publication number Publication date
CA2288307A1 (fr) 2001-05-15

Similar Documents

Publication Publication Date Title
US20100015153A1 (en) Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells and Antibodies That Identify the Same
EP1240326B1 (fr) Recepteur de declenchement implique dans la cytotoxicite naturelle induite par les lymphocytes tueurs naturels (natural killer cells) d'origine humaine et anticorps permettant d'identifier ce recepteur
Pende et al. Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells
Cantoni et al. Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells
WO1994027638A1 (fr) Anticorps monoclonaux bloquant l'adhesion du ligand sur le recepteur cd22 dans les lymphocytes b matures
WO1993021318A1 (fr) Antigene hb15 d'activation lymphocytaire appartenant au sous-ordre des immunoglobulines
WO1995029236A2 (fr) Antigenes d'activation de lymphocytes et anticorps correspondants
WO1995029236A9 (fr) Antigenes d'activation de lymphocytes et anticorps correspondants
AU676325B2 (en) Receptors of interleukin-12 and antibodies
US7138243B2 (en) NTB-A, a surface molecule involved in natural killer cells activity
AU2002325333A1 (en) NTB-A, a surface molecule involved in natural killer cells activity
WO1998003551A1 (fr) Ligand de cd6
WO1996034880A1 (fr) Ligand cd6
US20080248045A1 (en) Polypeptides having a triggering nk activity and biological applications
CA2288307C (fr) Recepteur activateur nouveau entrant en jeu dans la cytoxicite naturelle induite par les cellules nk humaines et anticorps revelant sa presence

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20161115