CA2301592A1 - Appareil et procede d'electrofluidite capillaire - Google Patents
Appareil et procede d'electrofluidite capillaire Download PDFInfo
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- CA2301592A1 CA2301592A1 CA002301592A CA2301592A CA2301592A1 CA 2301592 A1 CA2301592 A1 CA 2301592A1 CA 002301592 A CA002301592 A CA 002301592A CA 2301592 A CA2301592 A CA 2301592A CA 2301592 A1 CA2301592 A1 CA 2301592A1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
- B01J2219/00912—Separation by electrophoresis
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La présente invention concerne un appareil pouvant réaliser un procédé microfluidique. L'appareil comprend une première et une deuxième plaques intégrées (100, 110). La première plaque (100) comprend un réseau de récepteurs d'échantillons (102) pour recevoir une pluralité d'échantillons d'une série de contenants d'échantillons et distribuer les échantillons. La deuxième (110) comprend une série planaire de réseaux microfluidiques de structures à cavités et canaux pour réaliser un procédé microfluidique. L'invention concerne également un procédé de préparation d'une série d'échantillons. Au moins une partie de chaque échantillon d'un réseau de cupules d'échantillons est simultanément transférée vers une série correspondante de réseaux microfluidiques de moyens de structures à cavités et canaux d'une série correspondante de récepteurs d'échantillons communiquant solidairement avec la série de réseaux microfluidiques. Les échantillons sont ensuite traités. L'invention concerne en outre un dispositif servant à réaliser un procédé microfluidique, qui comprend un substrat planaire muni d'une série de réseaux microfluidiques de structures et canaux de cavité servant à réaliser un procédé microfluidique. Une pluralité de tels dispositifs peut être présente sur une feuille continue. L'invention concerne enfin des trousses comportant un appareil tel que décrit ci-dessus et servant à réaliser des procédés microfluidiques.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6758097P | 1997-09-19 | 1997-09-19 | |
| US60/067,580 | 1997-09-19 | ||
| PCT/US1998/018249 WO1999015888A1 (fr) | 1997-09-19 | 1998-09-15 | Appareil et procede d'electrofluidite capillaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2301592A1 true CA2301592A1 (fr) | 1999-04-01 |
Family
ID=22076988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002301592A Abandoned CA2301592A1 (fr) | 1997-09-19 | 1998-09-15 | Appareil et procede d'electrofluidite capillaire |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1019712A4 (fr) |
| JP (1) | JP2001517794A (fr) |
| AU (1) | AU753307B2 (fr) |
| CA (1) | CA2301592A1 (fr) |
| WO (1) | WO1999015888A1 (fr) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143152A (en) * | 1997-11-07 | 2000-11-07 | The Regents Of The University Of California | Microfabricated capillary array electrophoresis device and method |
| DE19819537A1 (de) * | 1998-04-30 | 2000-03-16 | Biochip Technologies Gmbh | Analyse- und Diagnostikinstrument |
| US6349740B1 (en) * | 1999-04-08 | 2002-02-26 | Abbott Laboratories | Monolithic high performance miniature flow control unit |
| JP3417344B2 (ja) | 1999-05-26 | 2003-06-16 | 株式会社島津製作所 | 化学発光検出方法及びその方法を用いたマイクロチップ電気泳動装置 |
| DE19926985B4 (de) * | 1999-06-14 | 2004-12-02 | Richard Dr. Reinhardt | Verfahren und Vorrichtung zur Gelelektrophorese |
| GB2368640B (en) * | 1999-08-13 | 2003-09-17 | Cartesian Technologies Inc | Apparatus for liquid sample handling |
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| US5571410A (en) * | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
| US5603351A (en) * | 1995-06-07 | 1997-02-18 | David Sarnoff Research Center, Inc. | Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device |
| US5560811A (en) * | 1995-03-21 | 1996-10-01 | Seurat Analytical Systems Incorporated | Capillary electrophoresis apparatus and method |
| US5872010A (en) * | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
-
1998
- 1998-09-15 CA CA002301592A patent/CA2301592A1/fr not_active Abandoned
- 1998-09-15 JP JP2000513135A patent/JP2001517794A/ja active Pending
- 1998-09-15 AU AU94721/98A patent/AU753307B2/en not_active Ceased
- 1998-09-15 EP EP98948072A patent/EP1019712A4/fr not_active Withdrawn
- 1998-09-15 WO PCT/US1998/018249 patent/WO1999015888A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU753307B2 (en) | 2002-10-17 |
| WO1999015888A1 (fr) | 1999-04-01 |
| EP1019712A1 (fr) | 2000-07-19 |
| JP2001517794A (ja) | 2001-10-09 |
| EP1019712A4 (fr) | 2002-08-07 |
| AU9472198A (en) | 1999-04-12 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |