CA2302780A1 - Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto - Google Patents

Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto Download PDF

Info

Publication number: CA2302780A1
Authority: CA; Canada
Prior art keywords: hedgehog; leu; ala; muscle; gly
Prior art date: 1997-08-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002302780A

Other languages

English (en)

French (fr)

Inventor

Chris S. Bladgen

Peter D. Currie

Philip W. Ingham

Simon M. Hughes

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Ontogeny Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-29

Filing date

1998-08-28

Publication date

1999-03-04

1998-08-28 Application filed by Ontogeny Inc filed Critical Ontogeny Inc

1999-03-04 Publication of CA2302780A1 publication Critical patent/CA2302780A1/en

Status Abandoned legal-status Critical Current

Links

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Marine Sciences & Fisheries (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

CA002302780A 1997-08-29 1998-08-28 Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto Abandoned CA2302780A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5739497P	1997-08-29	1997-08-29
US60/057,394		1997-08-29
PCT/US1998/017922 WO1999010004A2 (en)	1997-08-29	1998-08-28	Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto

Publications (1)

Publication Number	Publication Date
CA2302780A1 true CA2302780A1 (en)	1999-03-04

Family

ID=22010324

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002302780A Abandoned CA2302780A1 (en)	1997-08-29	1998-08-28	Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto

Country Status (4)

Country	Link
EP (1)	EP1009424A2 (de)
AU (1)	AU9125298A (de)
CA (1)	CA2302780A1 (de)
WO (1)	WO1999010004A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999000117A2 (en)	1997-06-27	1999-01-07	Ontogeny, Inc.	Neuroprotective methods and reagents
US7144997B2 (en)	1997-07-24	2006-12-05	Curis, Inc.	Vertebrate embryonic patterning-inducing proteins, compositions and uses related therto
US6891082B2 (en) *	1997-08-01	2005-05-10	The Johns Hopkins University School Of Medicine	Transgenic non-human animals expressing a truncated activintype II receptor
US6639051B2 (en)	1997-10-20	2003-10-28	Curis, Inc.	Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
US6884770B1 (en)	1998-11-06	2005-04-26	Curis, Inc.	Methods and compositions for treating or preventing peripheral neuropathies
US20030083242A1 (en) *	1998-11-06	2003-05-01	Alphonse Galdes	Methods and compositions for treating or preventing peripheral neuropathies
AU2724500A (en) *	1999-01-14	2000-08-01	Eli Lilly And Company	Use of desert hedgehog protein
EP1183271A1 (de) *	1999-06-01	2002-03-06	Biogen, Inc.	Polymer-konjugate von hedgehog-proteinen und deren verwendungen
US6545005B1 (en) *	1999-09-16	2003-04-08	Curtis, Inc.	Mediators of hedgehog signaling pathways, compositions and uses related thereto
US20070021493A1 (en)	1999-09-16	2007-01-25	Curis, Inc.	Mediators of hedgehog signaling pathways, compositions and uses related thereto
US8852937B2 (en)	2000-03-30	2014-10-07	Curis, Inc.	Small organic molecule regulators of cell proliferation
US6683108B1 (en) *	2000-03-30	2004-01-27	Curis, Inc.	Agonists of hedgehog signaling pathways and uses related thereto
US6683192B2 (en) *	2000-03-30	2004-01-27	Curis, Inc.	Small organic molecule regulators of cell proliferation
US7115653B2 (en)	2000-03-30	2006-10-03	Curis, Inc.	Small organic molecule regulators of cell proliferation
US7498304B2 (en)	2000-06-16	2009-03-03	Curis, Inc.	Angiogenesis-modulating compositions and uses
DK1387674T3 (en)	2000-10-13	2017-04-10	Curis Inc	Hedgehog antagonists, methods and uses related thereto
US7708998B2 (en)	2000-10-13	2010-05-04	Curis, Inc.	Methods of inhibiting unwanted cell proliferation using hedgehog antagonists
ES2707393T3 (es)	2004-03-26	2019-04-03	Curis Inc	Moduladores de interferencia de ARN de señalización de hedgehog y usos de los mismos
KR20100116177A (ko) *	2008-01-29	2010-10-29	노파르티스 아게	근골격-관련 장애의 치료에서 헤지호그 효능제의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3942114C2 (de) *	1988-12-26	1997-09-04	Hiroyoshi Hidaka	Verbindungen mit einer Wirkung für eine gleichmäßige Gefäßmuskelentspannung und pharmazeutische Zusammensetzung, die diese enthält
CA2179029C (en) *	1993-12-30	2009-02-24	Philip W. Ingham	Vertebrate embryonic pattern-inducing hedgehog-like proteins
US6281332B1 (en) *	1994-12-02	2001-08-28	The Johns Hopkins University School Of Medicine	Hedgehog-derived polypeptides
AU6714396A (en) *	1995-07-28	1997-02-26	Trustees Of Boston University	Methods and compositions for treating cell proliferative disorders
WO1998048830A1 (en) *	1997-04-28	1998-11-05	Trustees Of The University Of Pennsylvania	Method for promoting myogenesis using osteogenic proteins

1998
- 1998-08-28 CA CA002302780A patent/CA2302780A1/en not_active Abandoned
- 1998-08-28 EP EP98943462A patent/EP1009424A2/de not_active Withdrawn
- 1998-08-28 WO PCT/US1998/017922 patent/WO1999010004A2/en not_active Ceased
- 1998-08-28 AU AU91252/98A patent/AU9125298A/en not_active Abandoned

Also Published As

Publication number	Publication date
AU9125298A (en)	1999-03-16
WO1999010004A3 (en)	1999-05-27
EP1009424A2 (de)	2000-06-21
WO1999010004A2 (en)	1999-03-04

Legal Events

Date	Code	Title	Description
2004-06-01	FZDE	Discontinued

Publication	Publication Date	Title
AU760939B2 (en)	2003-05-22	Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
CA2302780A1 (en)	1999-03-04	Regulation of muscle tissues by hedgehog-like polypeptides, and formulations and uses related thereto
US20110124580A1 (en)	2011-05-26	Regulation of lung tissue by hedgehog-like polypeptides, and formulations and uses related thereto
EP1067917B1 (de)	2005-12-07	Methode zur behandlung von dopaminergen und gaba-nergen störungen
CA2349498A1 (en)	2000-05-18	Methods and compositions for treating or preventing peripheral neuropathies
EP1646395B1 (de)	2014-11-05	Verfahren und zusammensetzungen zur regulierung der lymphozytenaktivität
US6884770B1 (en)	2005-04-26	Methods and compositions for treating or preventing peripheral neuropathies
US6951839B1 (en)	2005-10-04	Methods and compositions for regulating lymphocyte activity
US20030162698A1 (en)	2003-08-28	Methods and compositions for treating dopaminergic and gaba-nergic disorders
AU763032B2 (en)	2003-07-10	Methods and compositions for treating disorders involving excitotoxicity
AU2003200161B2 (en)	2004-12-02	Method of treating dopaminergic and gaba-nergic disorders
US20080221037A1 (en)	2008-09-11	Methods and compositions for treating disorders involving excitotoxicity
HK1030365B (en)	2004-09-24	Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto