CA2303384A1 - Systeme de detection d'aliments contamines - Google Patents
Systeme de detection d'aliments contamines Download PDFInfo
- Publication number
- CA2303384A1 CA2303384A1 CA002303384A CA2303384A CA2303384A1 CA 2303384 A1 CA2303384 A1 CA 2303384A1 CA 002303384 A CA002303384 A CA 002303384A CA 2303384 A CA2303384 A CA 2303384A CA 2303384 A1 CA2303384 A1 CA 2303384A1
- Authority
- CA
- Canada
- Prior art keywords
- food
- antibodies
- layer
- antigen
- food contamination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000011109 contamination Methods 0.000 title claims abstract description 67
- 238000001514 detection method Methods 0.000 title claims abstract description 64
- 235000013305 food Nutrition 0.000 title claims abstract description 62
- 239000000463 material Substances 0.000 claims abstract description 27
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 23
- 239000002250 absorbent Substances 0.000 claims abstract description 22
- 230000002745 absorbent Effects 0.000 claims abstract description 22
- 239000013039 cover film Substances 0.000 claims abstract description 20
- 239000000427 antigen Substances 0.000 claims description 57
- 108091007433 antigens Proteins 0.000 claims description 57
- 102000036639 antigens Human genes 0.000 claims description 57
- 239000012528 membrane Substances 0.000 claims description 35
- 239000004005 microsphere Substances 0.000 claims description 17
- 239000004816 latex Substances 0.000 claims description 12
- 229920000126 latex Polymers 0.000 claims description 12
- 239000012530 fluid Substances 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 10
- 239000011358 absorbing material Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 230000001681 protective effect Effects 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 33
- 239000000758 substrate Substances 0.000 description 18
- 229920003023 plastic Polymers 0.000 description 12
- 239000007788 liquid Substances 0.000 description 11
- 239000004033 plastic Substances 0.000 description 11
- 239000000123 paper Substances 0.000 description 10
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 9
- 239000002953 phosphate buffered saline Substances 0.000 description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 8
- 230000008859 change Effects 0.000 description 8
- 239000000356 contaminant Substances 0.000 description 8
- 239000010408 film Substances 0.000 description 8
- 231100000765 toxin Toxicity 0.000 description 7
- 239000003053 toxin Substances 0.000 description 7
- 108700012359 toxins Proteins 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 6
- 229940098773 bovine serum albumin Drugs 0.000 description 6
- 238000003556 assay Methods 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 241000251468 Actinopterygii Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 4
- 238000007654 immersion Methods 0.000 description 4
- 239000012064 sodium phosphate buffer Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 229920002799 BoPET Polymers 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000005041 Mylar™ Substances 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000001579 optical reflectometry Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- RIRGCFBBHQEQQH-KFAHYOAQSA-N (2r,3s,4r,5r)-2-(hydroxymethyl)-5-[6-[[(2s)-1-phenylpropan-2-yl]amino]purin-9-yl]oxolane-3,4-diol Chemical compound C([C@H](C)NC=1C=2N=CN(C=2N=CN=1)[C@H]1[C@@H]([C@H](O)[C@@H](CO)O1)O)C1=CC=CC=C1 RIRGCFBBHQEQQH-KFAHYOAQSA-N 0.000 description 2
- 206010016952 Food poisoning Diseases 0.000 description 2
- 208000019331 Foodborne disease Diseases 0.000 description 2
- 239000004471 Glycine Substances 0.000 description 2
- 241000186781 Listeria Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 231100000678 Mycotoxin Toxicity 0.000 description 2
- 231100000769 Phycotoxin Toxicity 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000002636 mycotoxin Substances 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- MUXUBPXAMABMBB-UHFFFAOYSA-N 3-amino-6-chloro-n-(diaminomethylidene)-5-piperidin-1-ylpyrazine-2-carboxamide Chemical compound N1=C(N)C(C(=O)N=C(N)N)=NC(Cl)=C1N1CCCCC1 MUXUBPXAMABMBB-UHFFFAOYSA-N 0.000 description 1
- 241000589876 Campylobacter Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 239000004836 Glue Stick Substances 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920006328 Styrofoam Polymers 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229930188356 brevetoxin Natural products 0.000 description 1
- 239000011111 cardboard Substances 0.000 description 1
- WTXGTTBOKVQBGS-ZOTXBKINSA-N chembl1077122 Chemical compound C(/[C@H]1O[C@H]2C[C@H]3O[C@H](CC(=C)C=O)C[C@H](O)[C@]3(C)O[C@@H]2C[C@@H]1O[C@@H]1C2)=C/C[C@@H]1O[C@H]1[C@@]2(C)O[C@]2(C)CC[C@@H]3O[C@@H]4C[C@]5(C)O[C@@H]6C(C)=CC(=O)O[C@H]6C[C@H]5O[C@H]4C[C@@H](C)[C@H]3O[C@H]2C1 WTXGTTBOKVQBGS-ZOTXBKINSA-N 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- VYVRIXWNTVOIRD-UHFFFAOYSA-N ciguatoxin Natural products O1C(C(C(C)C2OC3CC(C)CC4OC5(C)C(O)CC6OC7C=CC8OC9CC%10C(C(C%11OC(C=CCC%11O%10)C=CC(O)CO)O)OC9C=CC8OC7CC=CCC6OC5CC4OC3CC2O2)O)C2C(C)C(C)C21CC(O)CO2 VYVRIXWNTVOIRD-UHFFFAOYSA-N 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000001268 conjugating effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 235000020200 pasteurised milk Nutrition 0.000 description 1
- 235000020030 perry Nutrition 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 235000020995 raw meat Nutrition 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000008261 styrofoam Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
Cette invention concerne un indicateur de contamination des aliments, qui comprend une première couche servant de support imperméable, une deuxième couche et une troisième couche constituée d'un film de revêtement imperméable. La deuxième couche contient un matériau absorbant, qui permet l'écoulement direct de divers jus, un tampon pour une solution "d'immuno-perles", et une zone de détection. La couche capillaire, qui repose sur la couche de support imperméable, est recouverte par la troisième couche en film de revêtement imperméable: de cette manière, la couche capillaire réside entre la couche de support imperméable et la troisième couche en film de revêtement imperméable.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5887397P | 1997-09-15 | 1997-09-15 | |
| US60/058,873 | 1997-09-15 | ||
| PCT/US1998/019167 WO1999014598A1 (fr) | 1997-09-15 | 1998-09-15 | Systeme de detection pour aliments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2303384A1 true CA2303384A1 (fr) | 1999-03-25 |
Family
ID=22019438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002303384A Abandoned CA2303384A1 (fr) | 1997-09-15 | 1998-09-15 | Systeme de detection d'aliments contamines |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1018013A1 (fr) |
| JP (1) | JP2001516883A (fr) |
| CN (1) | CN1278920A (fr) |
| AU (1) | AU9483998A (fr) |
| CA (1) | CA2303384A1 (fr) |
| NO (1) | NO20001297L (fr) |
| WO (1) | WO1999014598A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4109101A1 (fr) * | 2021-06-24 | 2022-12-28 | Technische Universität München | Dispositif de test portable pour tester la susceptibilité d'une sonde biologique à une ou plusieurs substances bioactives |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000020863A1 (fr) * | 1998-10-06 | 2000-04-13 | Verseau Group | Detecteur de toxines |
| DE102004052729A1 (de) * | 2004-10-30 | 2006-05-04 | Roche Diagnostics Gmbh | Immunkomplex-spezifsicher Antikörper zur Reduktion des Nullwerts beim Nachweis von Antigen-spezifisch gebundenen Antikörpern einer bestimmten Immunglobulinklasse in Array-Testformaten |
| GB2427271A (en) * | 2005-06-16 | 2006-12-20 | Porvair Filtration Group Ltd | Diagnostic device |
| WO2013115478A1 (fr) * | 2012-02-03 | 2013-08-08 | 동국대학교 산학협력단 | Kit d'emballage alimentaire permettant de détecter des bactéries |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981786A (en) * | 1987-09-04 | 1991-01-01 | Syntex (U.S.A.) Inc. | Multiple port assay device |
| US5958339A (en) * | 1992-08-31 | 1999-09-28 | Clinical Diagnostic Systems, Inc. | Format for immunoassay in thin film |
| DK0699304T3 (da) * | 1993-05-19 | 2000-05-29 | California South Pacific Investors | Detektering af forurenende stoffer i levnedsmidler |
| US5306466A (en) * | 1993-05-19 | 1994-04-26 | California South Pacific Investors | Detection of contaminants in food |
| DE69733494D1 (de) * | 1996-09-30 | 2005-07-14 | California South Pacific Investors | Nachweis von Verunreinigungen in Lebensmitteln |
-
1998
- 1998-09-15 AU AU94839/98A patent/AU9483998A/en not_active Abandoned
- 1998-09-15 EP EP98948221A patent/EP1018013A1/fr not_active Withdrawn
- 1998-09-15 CN CN98811173A patent/CN1278920A/zh active Pending
- 1998-09-15 JP JP2000512083A patent/JP2001516883A/ja active Pending
- 1998-09-15 CA CA002303384A patent/CA2303384A1/fr not_active Abandoned
- 1998-09-15 WO PCT/US1998/019167 patent/WO1999014598A1/fr not_active Ceased
-
2000
- 2000-03-13 NO NO20001297A patent/NO20001297L/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4109101A1 (fr) * | 2021-06-24 | 2022-12-28 | Technische Universität München | Dispositif de test portable pour tester la susceptibilité d'une sonde biologique à une ou plusieurs substances bioactives |
| WO2022268827A1 (fr) | 2021-06-24 | 2022-12-29 | Technische Universität München | Dispositif de test portatif pour test de sensibilité d'une sonde biologique à une ou plusieurs substances bioactives |
Also Published As
| Publication number | Publication date |
|---|---|
| NO20001297D0 (no) | 2000-03-13 |
| CN1278920A (zh) | 2001-01-03 |
| NO20001297L (no) | 2000-05-15 |
| JP2001516883A (ja) | 2001-10-02 |
| EP1018013A1 (fr) | 2000-07-12 |
| WO1999014598A1 (fr) | 1999-03-25 |
| AU9483998A (en) | 1999-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |