CA2305432A1 - Method for preventing the misuse of a transdermal therapeutic system - Google Patents

Method for preventing the misuse of a transdermal therapeutic system Download PDF

Info

Publication number
CA2305432A1
CA2305432A1 CA002305432A CA2305432A CA2305432A1 CA 2305432 A1 CA2305432 A1 CA 2305432A1 CA 002305432 A CA002305432 A CA 002305432A CA 2305432 A CA2305432 A CA 2305432A CA 2305432 A1 CA2305432 A1 CA 2305432A1
Authority
CA
Canada
Prior art keywords
misuse
preventing
therapeutic system
transdermal therapeutic
transdermal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002305432A
Other languages
French (fr)
Other versions
CA2305432C (en
Inventor
Frank Becher
Ann-Katrin Klink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2305432A1 publication Critical patent/CA2305432A1/en
Application granted granted Critical
Publication of CA2305432C publication Critical patent/CA2305432C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)

Abstract

Denaturants are added to a transdermal therapeutic system to prevent an improper, i.e. oral, application.
CA002305432A 1997-10-01 1998-09-18 Method for preventing the misuse of a transdermal therapeutic system Expired - Lifetime CA2305432C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19743484A DE19743484C1 (en) 1997-10-01 1997-10-01 Transdermal patches containing substance with unpleasant taste
DE19743484.3 1997-10-01
PCT/EP1998/005955 WO1999016428A1 (en) 1997-10-01 1998-09-18 Method for preventing the misuse of a transdermal therapeutic system

Publications (2)

Publication Number Publication Date
CA2305432A1 true CA2305432A1 (en) 1999-04-08
CA2305432C CA2305432C (en) 2007-04-03

Family

ID=7844345

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002305432A Expired - Lifetime CA2305432C (en) 1997-10-01 1998-09-18 Method for preventing the misuse of a transdermal therapeutic system

Country Status (22)

Country Link
EP (1) EP1019032B1 (en)
JP (2) JP4755338B2 (en)
KR (1) KR100552102B1 (en)
AT (1) ATE228356T1 (en)
AU (1) AU759609B2 (en)
CA (1) CA2305432C (en)
DE (2) DE19743484C1 (en)
DK (1) DK1019032T3 (en)
ES (1) ES2188021T3 (en)
HU (1) HU226644B1 (en)
ID (1) ID24333A (en)
IL (1) IL134479A (en)
MY (1) MY116425A (en)
NO (2) NO319163B1 (en)
NZ (1) NZ503643A (en)
PL (1) PL193066B1 (en)
PT (1) PT1019032E (en)
SK (1) SK3332000A3 (en)
TR (1) TR200000461T2 (en)
TW (1) TW431894B (en)
WO (1) WO1999016428A1 (en)
ZA (1) ZA988904B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19743484C1 (en) * 1997-10-01 1999-01-28 Lohmann Therapie Syst Lts Transdermal patches containing substance with unpleasant taste
GB0026137D0 (en) * 2000-10-25 2000-12-13 Euro Celtique Sa Transdermal dosage form
US7867511B2 (en) * 2004-01-23 2011-01-11 Travanti Pharma Inc. Abuse potential reduction in abusable substance dosage form
DE102004019916A1 (en) * 2004-04-21 2005-11-17 Grünenthal GmbH Anti-abuse drug-containing patch
CN112823191A (en) * 2018-10-17 2021-05-18 日荣新化株式会社 Adhesive sheet and method for producing same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5149538A (en) * 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
DE4342174C1 (en) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermal therapeutic system and a method for producing a transdermal therapeutic system for the combined transdermal application of physostigmine and scopolamine for the prophylaxis and pretreatment of poisoning by highly toxic organophosphorus neurotoxins, in particular Soman and its use
DE19743484C1 (en) * 1997-10-01 1999-01-28 Lohmann Therapie Syst Lts Transdermal patches containing substance with unpleasant taste

Also Published As

Publication number Publication date
PL193066B1 (en) 2007-01-31
MY116425A (en) 2004-01-31
DE19743484C1 (en) 1999-01-28
HK1029919A1 (en) 2001-04-20
JP4755338B2 (en) 2011-08-24
HUP0003476A2 (en) 2001-02-28
SK3332000A3 (en) 2000-11-07
ID24333A (en) 2000-07-13
HUP0003476A3 (en) 2001-04-28
AU9626598A (en) 1999-04-23
TW431894B (en) 2001-05-01
ZA988904B (en) 1999-04-12
IL134479A (en) 2005-07-25
NO20001492D0 (en) 2000-03-22
NO20001691L (en) 2000-03-31
JP2001517695A (en) 2001-10-09
KR100552102B1 (en) 2006-02-13
TR200000461T2 (en) 2000-09-21
EP1019032A1 (en) 2000-07-19
ES2188021T3 (en) 2003-06-16
HU226644B1 (en) 2009-05-28
CA2305432C (en) 2007-04-03
WO1999016428A1 (en) 1999-04-08
KR20010030886A (en) 2001-04-16
ATE228356T1 (en) 2002-12-15
PL339736A1 (en) 2001-01-02
IL134479A0 (en) 2001-04-30
NZ503643A (en) 2003-05-30
DE59806468D1 (en) 2003-01-09
AU759609B2 (en) 2003-04-17
NO319163B1 (en) 2005-06-27
DK1019032T3 (en) 2003-03-10
NO20001492L (en) 2000-03-22
JP2009035561A (en) 2009-02-19
PT1019032E (en) 2003-04-30
EP1019032B1 (en) 2002-11-27
NO20001691D0 (en) 2000-03-31

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20180918