CA2307499A1 - Method and apparatus for mixing and separating particulate matter from a liquid specimen - Google Patents

Method and apparatus for mixing and separating particulate matter from a liquid specimen Download PDF

Info

Publication number
CA2307499A1
CA2307499A1 CA002307499A CA2307499A CA2307499A1 CA 2307499 A1 CA2307499 A1 CA 2307499A1 CA 002307499 A CA002307499 A CA 002307499A CA 2307499 A CA2307499 A CA 2307499A CA 2307499 A1 CA2307499 A1 CA 2307499A1
Authority
CA
Canada
Prior art keywords
particulate matter
mixing
separating particulate
liquid specimen
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002307499A
Other languages
French (fr)
Other versions
CA2307499C (en
Inventor
Raouf A. Guirguis
Mark T. Maclean-Blevins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lamina Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2307499A1 publication Critical patent/CA2307499A1/en
Application granted granted Critical
Publication of CA2307499C publication Critical patent/CA2307499C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1058—General features of the devices using the transfer device for another function for mixing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Landscapes

  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

An apparatus for separating particulate matter from a fluid includes a collection container, a porous arrangement positioned in a housing and suitable for collecting particulate matter in the liquid on a collection site, and a pump. The apparatus is used to collect a uniform monolayer of cells from a biogical fluid, especially for use in cytology.
CA002307499A 1997-11-04 1998-11-04 Method and apparatus for mixing and separating particulate matter from a liquid specimen Expired - Fee Related CA2307499C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6427197P 1997-11-04 1997-11-04
US60/064,271 1997-11-04
PCT/US1998/023222 WO1999023468A1 (en) 1997-11-04 1998-11-04 Method and apparatus for mixing and separating particulate matter from a liquid specimen

Publications (2)

Publication Number Publication Date
CA2307499A1 true CA2307499A1 (en) 1999-05-14
CA2307499C CA2307499C (en) 2006-08-01

Family

ID=22054758

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002307499A Expired - Fee Related CA2307499C (en) 1997-11-04 1998-11-04 Method and apparatus for mixing and separating particulate matter from a liquid specimen

Country Status (9)

Country Link
US (2) US6296764B1 (en)
EP (1) EP1029228B1 (en)
JP (1) JP4074058B2 (en)
KR (1) KR100883817B1 (en)
AT (1) ATE214479T1 (en)
AU (1) AU749820B2 (en)
CA (1) CA2307499C (en)
DE (1) DE69804239T2 (en)
WO (1) WO1999023468A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114964905A (en) * 2022-07-26 2022-08-30 天津市水产研究所 An offshore seawater sediment collection device

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423237B1 (en) * 1992-07-28 2002-07-23 Lamina, Inc. Method and apparatus for manually separating particulate matter from a liquid specimen
ATE214479T1 (en) * 1997-11-04 2002-03-15 Monogen Inc METHOD AND APPARATUS FOR MIXING AND SEPARATING PARTICLE MATERIAL FROM A LIQUID SAMPLE
US6405609B1 (en) * 1998-02-27 2002-06-18 Ventana Medical Systems, Inc. System and method of aspirating and dispensing reagent
JP3898834B2 (en) * 1998-04-10 2007-03-28 富士フイルム株式会社 Blood continuous filtration device
US6830935B1 (en) * 1998-07-07 2004-12-14 Lamina, Inc. Method for mixing and processing specimen samples
DE19954713B4 (en) * 1999-11-13 2006-02-09 Forschungszentrum Jülich GmbH Device for hybridization of cells
US7708946B1 (en) * 2001-07-19 2010-05-04 Michael Sherman Device for protein detecting tests
WO2003034035A1 (en) * 2001-10-19 2003-04-24 Monogen, Inc. Vial system and method for processing liquid-based specimens
US7771662B2 (en) 2001-10-19 2010-08-10 Hologic, Inc Vial system and method for processing liquid-based specimens
WO2003034076A1 (en) * 2001-10-19 2003-04-24 Monogen, Inc. Article handling system and method
EP1845357A1 (en) * 2001-10-19 2007-10-17 MonoGen, Inc. Apparatus and method for mixing specimens in vials
US7270785B1 (en) 2001-11-02 2007-09-18 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
DK1890127T3 (en) 2002-04-15 2013-09-23 Ventana Med Syst Inc High capacity automated slide staining system
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
ES2556242T3 (en) 2002-04-26 2016-01-14 Ventana Medical Systems, Inc. Automated molecular pathology device that has fixed slide platforms
US6884341B2 (en) * 2002-10-02 2005-04-26 G6 Science Corp. Filter device to capture a desired amount of material
US6905594B2 (en) * 2002-10-11 2005-06-14 G6 Science Corp. Filter apparatus and methods to capture a desired amount of material from a sample suspension for monolayer deposition, analysis or other uses
EP1611942B1 (en) * 2004-06-07 2007-05-16 The Automation Partnership (Cambridge) Limited Stirring system for cell culture
CA2586893A1 (en) * 2004-11-09 2006-05-18 Monogen, Inc. Vial assembly, sampling apparatus and method for processing liquid-based specimens
EP1882524A4 (en) * 2005-05-17 2010-09-08 Universal Bio Research Co Ltd Filter processing method, filter encapsulation chip, and filter processing device
CA2646888A1 (en) 2006-03-20 2007-09-27 Rongshan Li Cytoblock preparation system and methods of use
CN101382510B (en) * 2007-09-06 2012-07-25 清华大学 Multi-bottle test container
CN102209889B (en) 2008-11-12 2015-05-13 文塔纳医疗系统公司 Methods and apparatuses for heating slides carrying specimens
US8333925B2 (en) * 2009-06-05 2012-12-18 Jeffrey Michael Holmes Ergonomic pipetting workstation
TWI413616B (en) * 2009-09-25 2013-11-01 Iner Aec Executive Yuan Wastewater treatment apparatus and method with stair-like heat treatment tanks
KR101912952B1 (en) * 2010-05-05 2018-10-29 베크만 쿨터 바이오메디컬, 엘엘씨 Diagnostic instrument and flow process
KR101168232B1 (en) * 2011-03-25 2012-07-30 바디텍메드 주식회사 Integrated sampling and dispensing device
GB201111080D0 (en) * 2011-06-29 2011-08-10 Ge Healthcare Uk Ltd Syringeless filter device compressor
JP5801124B2 (en) * 2011-07-14 2015-10-28 日本光電工業株式会社 Pipette member and cell isolation instrument
WO2013059526A1 (en) 2011-10-18 2013-04-25 The Trustees Of Columbia University In The City Of New York Medical apparatus and method for collecting biological samples
CN102608034B (en) * 2012-02-28 2014-07-23 何毅 A reagent prepackaged cuvette structure
US8690752B2 (en) 2012-08-03 2014-04-08 Alison Jane Jose Oocyte separation and collection system
DE102012108989B3 (en) 2012-09-24 2014-01-23 Eads Deutschland Gmbh Detection device and method for the automatic detection of particles
EP2902784B1 (en) * 2012-09-28 2018-10-24 National Institute of Advanced Industrial Science and Technology Assay device using porous medium
CN110074820A (en) 2012-11-20 2019-08-02 纽约哥伦比亚大学董事会 Medical Devices and method for collecting biological sample
US10302535B2 (en) 2013-09-12 2019-05-28 CellectGen, Inc. Biofluid collection and filtration device
WO2015038834A1 (en) * 2013-09-12 2015-03-19 CellectGen, Inc. Biofluid collection and filtration device
JP6165574B2 (en) * 2013-09-26 2017-07-19 シスメックス株式会社 Filter member and cell acquisition method
FR3012976B1 (en) * 2013-11-12 2016-07-29 Biocarecell DEVICE FOR FILTRATION OF BIOLOGICAL FLUID.
CN105793690B (en) 2013-12-13 2020-01-03 文塔纳医疗系统公司 Automated histological processing of biological samples and related techniques
JP6281945B2 (en) * 2014-03-11 2018-02-21 国立研究開発法人産業技術総合研究所 Assay device using porous media
JP6205299B2 (en) * 2014-03-31 2017-09-27 シチズンファインデバイス株式会社 Sample loading plate
CN105928757B (en) * 2014-04-23 2019-01-25 杭州电子科技大学 Automatic Cell Block Preparation System
EP2957886B1 (en) * 2014-06-17 2016-10-12 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Device for exposing test bodies in a liquid
JP6264465B2 (en) * 2014-09-02 2018-01-24 株式会社島津製作所 Pre-processing apparatus and analysis system provided with the same
CN116869527A (en) * 2015-01-30 2023-10-13 Emd密理博公司 Fluid delivery devices, systems and methods
DE102016123658B4 (en) * 2016-12-07 2021-10-07 Technische Universität Dresden Filtration device and method for the enrichment of targets and the subsequent release of biogenic agents
KR102061651B1 (en) * 2017-03-03 2020-01-02 사회복지법인 삼성생명공익재단 Pre-processing apparatus of object and method for pre-processing the object
CN111065904A (en) * 2017-08-02 2020-04-24 普凯尔德诊断技术有限公司 Processor filter arrangement including method and apparatus for removing waste liquid through filter
FR3080780B1 (en) * 2018-05-04 2021-07-09 Bertin Technologies Sa PARTICLE OR MICRO-ORGANISMS COLLECTION DEVICE
KR101985008B1 (en) * 2018-09-08 2019-05-31 (주)바이오다인 exfoliative cell processing device
ES3035146T3 (en) 2019-04-25 2025-08-29 Fremonta Corp Powered sampling device and method
CN110180274B (en) * 2019-05-30 2021-10-26 马鞍山科宇环境工程有限公司 Small-size portable dust collecting equipment
WO2020256628A1 (en) * 2019-06-20 2020-12-24 Amniotics Ab An apparatus for filtering amniotic fluid
CN112033745B (en) * 2020-07-25 2023-12-22 金丽琴 A sampling device for chemical laboratory analysis
US20230356212A1 (en) * 2020-10-06 2023-11-09 Foss Analytical A/S Method for determining dietary fiber and a sample container
US12435308B2 (en) 2020-11-06 2025-10-07 Amniotics Ab Immunomodulation by amniotic fluid mesenchymal stem cells
CN116726756B (en) * 2023-08-15 2023-10-24 福建紫金矿冶测试技术有限公司 Sample mixing equipment for mineral sample detection and application method thereof
CN118755558B (en) * 2024-09-06 2024-11-05 成都大学 Microbial fermentation device convenient to separate slag charge

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583230A (en) * 1968-06-12 1971-06-08 Sondell Research Dev Co Sample injection method and apparatus
US3802843A (en) * 1971-05-28 1974-04-09 American Hospital Supply Corp Fluid testing apparatus
GB1467428A (en) * 1973-08-17 1977-03-16 Strutt Farrands Ltd Filtration apparauts
AU547490B2 (en) * 1980-05-31 1985-10-24 Sanden Corporation Scroll-type pump
JPS5861469A (en) * 1981-10-08 1983-04-12 Mochida Pharmaceut Co Ltd Inclined rotating device for reactor
US4871683A (en) * 1985-04-18 1989-10-03 Beckman Instruments, Inc. Apparatus and method using a new reaction capsule
US4602995A (en) * 1985-05-20 1986-07-29 Technicon Instruments Corporation Liquid level adjusting and filtering device
US4921618A (en) * 1987-07-01 1990-05-01 Basf Corporation Inverted separation and transfer device, and process for using same
US5139031A (en) 1989-09-18 1992-08-18 La Mina Ltd. Method and device for cytology and microbiological testing
US5042502A (en) 1989-09-18 1991-08-27 La Mina Ltd. Urine testing module with cytology cup
US5301685A (en) 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US4953561A (en) 1989-09-18 1990-09-04 Cancer Diagnostics, Inc. Urine testing module and method of collecting urine antigen
US5016644A (en) 1989-01-10 1991-05-21 La Mina Ltd. Urine testing module and method of collecting urine antigen
US4879431A (en) * 1989-03-09 1989-11-07 Biomedical Research And Development Laboratories, Inc. Tubeless cell harvester
US5167926A (en) * 1989-09-13 1992-12-01 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for pretreating cells for flow cytometry
US5137031A (en) 1989-09-18 1992-08-11 La Mina Ltd. Urine testing apparatus with urinary sediment device
US5282978A (en) * 1990-07-09 1994-02-01 Cytyc Corporation Specimen processor method and apparatus
US5143627A (en) 1990-07-09 1992-09-01 Cytyc Corporation Method and apparatus for preparing cells for examination
US5324483B1 (en) * 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
US5236263A (en) * 1992-10-08 1993-08-17 Friedland Donald R Printing ink mixing apparatus
US5366620A (en) * 1993-04-01 1994-11-22 Upchurch Scientific, Inc. Inlet filter
US5624554A (en) * 1993-11-22 1997-04-29 Biomedical Polymers, Inc. Collection and transfer device
JP2955365B2 (en) * 1994-02-25 1999-10-04 デイステク インコーポレイテツド Dissolution test equipment
US5816701A (en) * 1996-04-22 1998-10-06 Source For Automation, Inc. Automated tablet dissolution apparatus
ATE214479T1 (en) * 1997-11-04 2002-03-15 Monogen Inc METHOD AND APPARATUS FOR MIXING AND SEPARATING PARTICLE MATERIAL FROM A LIQUID SAMPLE

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114964905A (en) * 2022-07-26 2022-08-30 天津市水产研究所 An offshore seawater sediment collection device
CN114964905B (en) * 2022-07-26 2022-10-25 天津市水产研究所 Offshore seawater sediment collection device

Also Published As

Publication number Publication date
US6379565B1 (en) 2002-04-30
KR20010031820A (en) 2001-04-16
WO1999023468A1 (en) 1999-05-14
DE69804239T2 (en) 2002-10-31
KR100883817B1 (en) 2009-02-16
DE69804239D1 (en) 2002-04-18
EP1029228B1 (en) 2002-03-13
EP1029228A1 (en) 2000-08-23
JP2001522042A (en) 2001-11-13
ATE214479T1 (en) 2002-03-15
AU1208199A (en) 1999-05-24
AU749820B2 (en) 2002-07-04
JP4074058B2 (en) 2008-04-09
CA2307499C (en) 2006-08-01
US6296764B1 (en) 2001-10-02

Similar Documents

Publication Publication Date Title
CA2176139A1 (en) Method and Apparatus for Collecting a Cell Sample from a Liquid Specimen
WO1998020352A3 (en) Method and apparatus for collecting a cell sample from a liquid specimen
CA2072331A1 (en) Sampling device and sample adequacy system
IL134404A (en) Method and apparatus for separating particulate matter from a liquid specimen
CA2075193A1 (en) Specimen test unit
AU2001267332A1 (en) Assembly for withdrawing and filtering partial volumes of process fluid
EP1038541A3 (en) System and method for processing biological fluids
CA2014119A1 (en) Methods and devices for the separation of plasma or serum from whole blood, collection of plasma or serum, and reagent delivery system
DE69804239D1 (en) METHOD AND APPARATUS FOR MIXING AND SEPARATING PARTICLE MATERIAL FROM A LIQUID SAMPLE
EP0832690A3 (en) Collection assembly with a reservoir
CA2304017A1 (en) Apparatuses and methods for isolating nucleic acid
EP1340982A3 (en) Assay work station
CA2255716A1 (en) Method and apparatus for collecting vaginal fluid and exfoliated vaginal cells for diagnostic purposes
CA2336093A1 (en) Improved method for mixing and processing specimen samples
US6629612B2 (en) Biological filtration station
CA2176699A1 (en) Mid-stream fluid sampler
EP1504812A4 (en) METHOD AND APPARATUS FOR COLLECTING A MICROMATERIAL
CA2039108A1 (en) Method and apparatus for detecting trace contaminents
BR9813936A (en) Method and apparatus for mixing and separating particulate matter from a liquid sample
JPS56118706A (en) Ventilating and stirring filter
CA2204251A1 (en) Method and apparatus for preparing substances for optical analysis
CA2181305A1 (en) Apparatus for collecting a mid-stream urine sample
CA2028098A1 (en) Apparatus for and method of managing liquid under pressure
WO2001072609A3 (en) Method and container for selectively collecting solid urban waste
EP0763736A3 (en) Analysis element and method for preparing the same

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20131105