CA2309033A1 - Emulsions specifiques de glandes lacrymales pour application topique sur le tissu oculaire - Google Patents

Emulsions specifiques de glandes lacrymales pour application topique sur le tissu oculaire Download PDF

Info

Publication number: CA2309033A1
Authority: CA; Canada
Prior art keywords: cyclosporin; lacrimal gland; topical application; ocular tissue; gland specific
Prior art date: 1994-05-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA002309033A

Other languages

English (en)

Other versions

CA2309033C (fr

Inventor

Shulin Ding

Walter L. Tien

Orest Olejnik

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Allergan Inc

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-17

Filing date

1995-05-17

Publication date

1995-11-23

1994-05-17 Priority claimed from US08/243,279 external-priority patent/US5474979A/en

1995-05-17 Application filed by Individual filed Critical Individual

1995-11-23 Publication of CA2309033A1 publication Critical patent/CA2309033A1/fr

2003-08-26 Application granted granted Critical

2003-08-26 Publication of CA2309033C publication Critical patent/CA2309033C/fr

2015-05-17 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000000839 emulsion Substances 0.000 title abstract 2
210000004561 lacrimal apparatus Anatomy 0.000 title abstract 2
210000001519 tissue Anatomy 0.000 title abstract 2
230000000699 topical effect Effects 0.000 title 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 4
229930105110 Cyclosporin A Natural products 0.000 abstract 4
108010036949 Cyclosporine Proteins 0.000 abstract 4
229960001265 ciclosporin Drugs 0.000 abstract 4
229930182912 cyclosporin Natural products 0.000 abstract 3
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
239000004359 castor oil Substances 0.000 abstract 1
235000019438 castor oil Nutrition 0.000 abstract 1
238000002425 crystallisation Methods 0.000 abstract 1
230000008025 crystallization Effects 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
230000007794 irritation Effects 0.000 abstract 1
238000002483 medication Methods 0.000 abstract 1
231100000344 non-irritating Toxicity 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
229920000053 polysorbate 80 Polymers 0.000 abstract 1
229940068968 polysorbate 80 Drugs 0.000 abstract 1

Landscapes

Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

CA002309033A 1994-05-17 1995-05-17 Emulsions specifiques de glandes lacrymales pour application topique sur le tissu oculaire Expired - Lifetime CA2309033C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/243,279 US5474979A (en)	1994-05-17	1994-05-17	Nonirritating emulsions for sensitive tissue
US08/243,279		1994-05-17
CA002190485A CA2190485C (fr)	1994-05-17	1995-05-17	Emulsion specifique de la glande lacrymale pour application locale sur les tissus de l'oeil

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002190485A Division CA2190485C (fr)	1994-05-17	1995-05-17	Emulsion specifique de la glande lacrymale pour application locale sur les tissus de l'oeil

Publications (2)

Publication Number	Publication Date
CA2309033A1 true CA2309033A1 (fr)	1995-11-23
CA2309033C CA2309033C (fr)	2003-08-26

Family

ID=25678827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002309033A Expired - Lifetime CA2309033C (fr)	1994-05-17	1995-05-17	Emulsions specifiques de glandes lacrymales pour application topique sur le tissu oculaire

Country Status (1)

Country	Link
CA (1)	CA2309033C (fr)

1995
- 1995-05-17 CA CA002309033A patent/CA2309033C/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2309033C (fr)	2003-08-26

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Legal Events

Date	Code	Title	Description
2000-05-30	EEER	Examination request
2015-07-21	MKEX	Expiry	Effective date: 20150519