CA2309354A1 - Gabapentine et ses derives pour le traitement de la douleur musculaire et squelettique - Google Patents

Gabapentine et ses derives pour le traitement de la douleur musculaire et squelettique Download PDF

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Publication number
CA2309354A1
CA2309354A1 CA002309354A CA2309354A CA2309354A1 CA 2309354 A1 CA2309354 A1 CA 2309354A1 CA 002309354 A CA002309354 A CA 002309354A CA 2309354 A CA2309354 A CA 2309354A CA 2309354 A1 CA2309354 A1 CA 2309354A1
Authority
CA
Canada
Prior art keywords
pain
gabapentin
day
muscular
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002309354A
Other languages
English (en)
Inventor
Leslie Magnus-Miller
Catherine A. Segal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2309354A1 publication Critical patent/CA2309354A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un procédé visant à utiliser certains analogues d'acide glutamique et d'acide gamma-aminobutyrique afin de soulager la douleur du dos de nature musculaire ou squelettique.
CA002309354A 1998-01-23 1999-01-22 Gabapentine et ses derives pour le traitement de la douleur musculaire et squelettique Abandoned CA2309354A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7239798P 1998-01-23 1998-01-23
US60/072,397 1998-01-23
PCT/US1999/001290 WO1999037296A1 (fr) 1998-01-23 1999-01-22 Gabapentine et ses derives pour le traitement de la douleur musculaire et squelettique

Publications (1)

Publication Number Publication Date
CA2309354A1 true CA2309354A1 (fr) 1999-07-29

Family

ID=22107298

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002309354A Abandoned CA2309354A1 (fr) 1998-01-23 1999-01-22 Gabapentine et ses derives pour le traitement de la douleur musculaire et squelettique

Country Status (4)

Country Link
EP (1) EP1047414A1 (fr)
AU (1) AU2463099A (fr)
CA (1) CA2309354A1 (fr)
WO (1) WO1999037296A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4334900A (en) 1999-04-09 2000-11-14 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
CA2392879C (fr) 1999-12-01 2005-03-29 Ucb, S.A. Derive de pyrrolidine acetamide seul ou combine pour traiter des affections du snc
DE10048714A1 (de) 2000-09-30 2002-04-11 Gruenenthal Gmbh 5-Amino-1-penlen-3-ol-Derivate
US6620829B2 (en) 2000-10-17 2003-09-16 Warner-Lambert Company Method of treating noninflammatory cartilage damage
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AU2002310409C1 (en) 2001-06-11 2008-04-17 Xenoport, Inc. Orally administered dosage forms of GABA analog prodrugs having reduced toxicity
EP1412324A4 (fr) 2001-06-11 2004-09-29 Xenoport Inc Conjugues d'amino acides permettant d'obtenir des concentrations systemiques soutenues d'analogues du gaba
JP4337138B2 (ja) * 2001-08-31 2009-09-30 味の素株式会社 新規ジアリールアルケン誘導体及び新規ジアリールアルカン誘導体
CN1274306C (zh) 2001-09-03 2006-09-13 纽朗制药有限公司 包含加巴喷丁或其类似物和α－氨基酰胺的药物组合物及其止痛应用
US6927036B2 (en) 2002-02-19 2005-08-09 Xero Port, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
WO2003099338A2 (fr) 2002-05-17 2003-12-04 Xenoport, Inc. Conjugues d'acides amines permettant d'obtenir des concentrations systemiques prolongees d'analogues gaba
AU2003297927A1 (en) 2002-12-11 2004-06-30 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
ATE449633T1 (de) * 2003-09-12 2009-12-15 Pfizer Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern
CA2538802C (fr) 2003-09-17 2015-01-27 Xenoport, Inc. Traitement ou prevention du syndrome des jambes sans repos a l'aide de promedicaments a base d'analogues du gaba
CA2541752C (fr) 2003-10-14 2012-01-03 Xenoport, Inc. Forme cristalline d'analogue d'acide gamma-aminobutyrique
EP1811986B1 (fr) 2004-11-04 2014-03-26 XenoPort, Inc. Formes posologiques orales a liberation prolongee d'un promedicament de la gabapentine
WO2007108001A2 (fr) * 2006-03-22 2007-09-27 Haim Dror Blecher Remodelage de ligament
EP2184986A4 (fr) * 2007-08-06 2010-12-15 Trinity Lab Inc Compositions pharmaceutiques pour le traitement de la douleur chronique et de la douleur associée à une neuropathie
JP7441181B2 (ja) 2018-05-14 2024-02-29 エックスジーン ファーマシューティカル インク． ナプロキセンとプレガバリンの１－（アシルオキシ）－アルキルカルバメート薬品複合体の結晶形態

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
EP1132082A1 (fr) * 1996-11-05 2001-09-12 Head Explorer ApS Utilisation des composés ayant une action inhibitrice sur la production de glutamate pour le traitement des cephalées de type tension nerveuse
WO1998046601A1 (fr) * 1997-04-11 1998-10-22 Eli Lilly And Company Composition pour le traitement de la douleur
HRP980342A2 (en) * 1997-06-25 1999-02-28 Warner Lambert Co Anti-inflammatory method

Also Published As

Publication number Publication date
WO1999037296A1 (fr) 1999-07-29
AU2463099A (en) 1999-08-09
EP1047414A1 (fr) 2000-11-02

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued