CA2309677A1 - Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques - Google Patents

Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques Download PDF

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Publication number
CA2309677A1
CA2309677A1 CA002309677A CA2309677A CA2309677A1 CA 2309677 A1 CA2309677 A1 CA 2309677A1 CA 002309677 A CA002309677 A CA 002309677A CA 2309677 A CA2309677 A CA 2309677A CA 2309677 A1 CA2309677 A1 CA 2309677A1
Authority
CA
Canada
Prior art keywords
sel
protein
gly
seq
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002309677A
Other languages
English (en)
Inventor
Dorit Donoviel
Alan Bernstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mt Sinai Hospital
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2309677A1 publication Critical patent/CA2309677A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une molécule d'acide nucléique, appelée Sel-IL (de type Sel-1, connue aussi sous le nom de Hip-1), qui est largement exprimée dans les souris adultes et les tissus humains avec des taux particulièrement élevés dans le pancréas et dans la partie plancher du tube neural. La Sel-IL peut aussi être localisée dans les vésicules intracellulaires. Le gène couvre 14q24.3-31 à proximité du locus du diabète insulino-dépendant (IDDML). La molécule d'acide nucléique code une protéine appelée "protéine SEL-IL".
CA002309677A 1997-11-19 1998-11-19 Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques Abandoned CA2309677A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6614097P 1997-11-19 1997-11-19
US60/066,140 1997-11-19
US12354998A 1998-07-28 1998-07-28
US09/123,549 1998-07-28
PCT/CA1998/001058 WO1999027088A2 (fr) 1997-11-19 1998-11-19 Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques

Publications (1)

Publication Number Publication Date
CA2309677A1 true CA2309677A1 (fr) 1999-06-03

Family

ID=26746413

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002309677A Abandoned CA2309677A1 (fr) 1997-11-19 1998-11-19 Nouveaux gene et proteine exprimes dans les tissus nerveux et pancreatiques

Country Status (2)

Country Link
CA (1) CA2309677A1 (fr)
WO (1) WO1999027088A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4058567B2 (ja) * 1997-11-28 2008-03-12 大塚製薬株式会社 Ｔｓａ３０５遺伝子
US6720173B1 (en) 1999-11-08 2004-04-13 Lexicon Genetics Incorporated Human kinase protein and polynucleotides encoding the same
AU1919401A (en) * 1999-11-17 2001-05-30 Lexicon Genetics Incorporated Novel human notch ligand proteins and polynucleotides encoding the same
EP1871163A2 (fr) * 2005-06-06 2008-01-02 Genentech, Inc. Nouvelles interruptions geniques, compositions et methodes associees

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU724054B2 (en) * 1995-08-17 2000-09-14 Regents Of The University Of California, The Genes and proteins controlling cholesterol synthesis
AU7521196A (en) * 1995-10-27 1997-05-15 Asahi Chemical Industry Co. Ltd. Peptide inhibitors of a phosphotyrosine-binding domain containing protein

Also Published As

Publication number Publication date
WO1999027088A2 (fr) 1999-06-03
WO1999027088A3 (fr) 1999-08-12

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Legal Events

Date Code Title Description
FZDE Discontinued