CA2323630A1 - Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germ es gram-negatifs associees aux lipopolysaccharides - Google Patents

Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germ es gram-negatifs associees aux lipopolysaccharides Download PDF

Info

Publication number: CA2323630A1
Authority: CA; Canada
Prior art keywords: bpi; lps; bactericidal; gram negative; endotoxin
Prior art date: 1989-02-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002323630A

Other languages

English (en)

Inventor

Marian N. Marra

Randal W. Scott

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Incyte Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-14

Filing date

1990-02-14

Publication date

1990-08-15

1990-01-22 Priority claimed from US07/468,696 external-priority patent/US5089274A/en

1990-02-14 Application filed by Individual filed Critical Individual

1990-08-15 Publication of CA2323630A1 publication Critical patent/CA2323630A1/fr

Status Abandoned legal-status Critical Current

Links

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Landscapes

Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA002323630A 1989-02-14 1990-02-14 Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germ es gram-negatifs associees aux lipopolysaccharides Abandoned CA2323630A1 (fr)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US31084289A	1989-02-14	1989-02-14
US310,842		1989-02-14
US468,696		1990-01-22
US07/468,696 US5089274A (en)	1989-02-14	1990-01-22	Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders
CA002048619A CA2048619C (fr)	1989-02-14	1990-02-14	Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germes gram-negatifs associees aux lipopolysaccharides

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002048619A Division CA2048619C (fr)	1989-02-14	1990-02-14	Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germes gram-negatifs associees aux lipopolysaccharides

Publications (1)

Publication Number	Publication Date
CA2323630A1 true CA2323630A1 (fr)	1990-08-15

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Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002323630A Abandoned CA2323630A1 (fr)	1989-02-14	1990-02-14	Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germ es gram-negatifs associees aux lipopolysaccharides

Country Status (1)

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CA (1)	CA2323630A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2016179560A1 (fr)	2015-05-06	2016-11-10	The Procter & Gamble Company	Détection de facteurs de virulence microbienne orale
US9964472B2 (en)	2016-06-29	2018-05-08	The Procter & Gamble Company	Methods for sampling gingival metabolites

1990
- 1990-02-14 CA CA002323630A patent/CA2323630A1/fr not_active Abandoned

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2016179560A1 (fr)	2015-05-06	2016-11-10	The Procter & Gamble Company	Détection de facteurs de virulence microbienne orale
US9970934B2 (en)	2015-05-06	2018-05-15	The Procter & Gamble Company	Detection of oral microbial virulence factors
US10156566B2 (en)	2015-05-06	2018-12-18	The Procter & Gamble Company	Detoxification of microbial virulence factors in oral cavity
US10267797B2 (en)	2015-05-06	2019-04-23	The Procter & Gamble Company	Detection of oral microbial virulence factors
US9964472B2 (en)	2016-06-29	2018-05-08	The Procter & Gamble Company	Methods for sampling gingival metabolites

Legal Events

Date	Code	Title	Description
2000-10-26	EEER	Examination request
2008-04-07	FZDE	Dead

Publication	Publication Date	Title
CA2048619C (fr)	2001-02-13	Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germes gram-negatifs associees aux lipopolysaccharides
Marra et al.	1990	Bactericidal/permeability-increasing protein has endotoxin-neutralizing activity.
US5171739A (en)	1992-12-15	Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5334584A (en)	1994-08-02	Recombinant, non-glycosylated bpi protein and uses thereof
US5308834A (en)	1994-05-03	Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
EP0610445B1 (fr)	2000-01-05	Utilisation de compositions comprenant une proteine a action bactericide/accroissant la permeabilite et un excipient lipidique
Ooi et al.	1991	Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils.
Marra et al.	1992	The role of bactericidal/permeability-increasing protein as a natural inhibitor of bacterial endotoxin
US6222021B1 (en)	2001-04-24	Fragments of endotoxin binding protein and uses thereof
DE3751741T2 (de)	1996-11-14	Antimikrobielle Proteine, Zusammensetzungen, welche dieselben enthalten, und deren Anwendungen
Weinrauch et al.	1995	Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate.
CA2298101A1 (fr)	1999-02-11	Nouveaux peptides synthetiques possedant des proprietes antimicrobiennes et de neutralisation d'endotoxines et permettant de lutter contre le syndrome de septicemie
DE69431922T2 (de)	2003-11-13	Glycosilierte und nichtglycolisierte bakterizide/die permeabilität erhoehende proteine und methoden zu ihrer herstellung
EP0586573B1 (fr)	2001-12-19	Proteine de liaison et de neutralisation d'endotoxine et ses utilisations
Ohno	2024	LPS binding proteins in granulocyte lysosomes
WO1996034873A1 (fr)	1996-11-07	Proteines de recombinaison neutralisant une endotoxine
Gray et al.	1994	Bactericidal activity of synthetic peptides based on the structure of the 55-kilodalton bactericidal protein from human neutrophils
CA2323630A1 (fr)	1990-08-15	Utilisation de proteines bactericides accroissant la permeabilite ou de leurs analogues actifs biologiquement pour traiter des infections a germ es gram-negatifs associees aux lipopolysaccharides
US5489676A (en)	1996-02-06	Polypeptides that potentiate bactericidal/permeability-increasing protein and methods for treating bacterial infections
Naberezhnykh et al.	2025	Biochemical characterization and antibacterial activity of lipopolysaccharide binding proteins of the jellyfish Aurelia aurita and Rhopilema asamushi
Vogel	2018	Cobra Venom Factor: The Complement-Activating
Wasiluk	1991	Killing of Pseudomonas aeruginosa and Pseudomonas cepacia by bactericidal proteins isolated from the cytoplasmic granules of human polymorphonuclear leukocytes
Gough Scott	1998	Comparison of structurally related peptides in their antimicrobial and anti-endotoxic activity