CA2340465A1 - Genes regulant les cellules souche hematopoietiques et utilisation de ces genes - Google Patents

Genes regulant les cellules souche hematopoietiques et utilisation de ces genes Download PDF

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Publication number
CA2340465A1
CA2340465A1 CA002340465A CA2340465A CA2340465A1 CA 2340465 A1 CA2340465 A1 CA 2340465A1 CA 002340465 A CA002340465 A CA 002340465A CA 2340465 A CA2340465 A CA 2340465A CA 2340465 A1 CA2340465 A1 CA 2340465A1
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CA
Canada
Prior art keywords
seq
stem cell
cells
cell
hematopoietic stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002340465A
Other languages
English (en)
Inventor
Ihor Lemischka
Kateri Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2340465A1 publication Critical patent/CA2340465A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un acide nucléique isolé dérivé d'une cellule souche hématopoïétique isolée. Elle concerne également une protéine spécifique de cellule souche hématopoïétique ou une portion de cette protéine codée par l'acide nucléique décrit. L'invention concerne en outre un procédé permettant de produire une cellule souche/cellule précurseur d'une cellule hématopoïétique primitive, ainsi qu'un procédé permettant d'identifier la présence d'un composant modulant l'activité des cellules souches hématopoïétiques dans un échantillon. De plus, L'invention concerne une cellule souche hématopoïétique primitive dont la composition moléculaire a été définie. Enfin L'invention concerne un procédé de culture ex vivo de cellules souches hématopoïétiques.
CA002340465A 1998-08-21 1999-08-20 Genes regulant les cellules souche hematopoietiques et utilisation de ces genes Abandoned CA2340465A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13813298A 1998-08-21 1998-08-21
US09/138,132 1998-08-21
PCT/US1999/019052 WO2000011168A2 (fr) 1998-08-21 1999-08-20 Genes regulant les cellules souche hematopoietiques et utilisation de ces genes

Publications (1)

Publication Number Publication Date
CA2340465A1 true CA2340465A1 (fr) 2000-03-02

Family

ID=22480559

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002340465A Abandoned CA2340465A1 (fr) 1998-08-21 1999-08-20 Genes regulant les cellules souche hematopoietiques et utilisation de ces genes

Country Status (5)

Country Link
EP (1) EP1105482A2 (fr)
JP (1) JP2002523044A (fr)
AU (1) AU5780999A (fr)
CA (1) CA2340465A1 (fr)
WO (1) WO2000011168A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7160679B1 (en) 1998-05-21 2007-01-09 Diadexus, Inc. Method of diagnosing, monitoring, and staging lung cancer
US20020137906A1 (en) * 2000-06-02 2002-09-26 Horvitz H. Robert Tumor suppressor pathway in C. elegans
US20020082191A1 (en) * 2000-12-08 2002-06-27 Karl Guegler Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2011040500A1 (fr) 2009-09-29 2011-04-07 国立大学法人九州大学 Peptide inhibant la différenciation des cellules souches hématopoïétiques ou des cellules précurseurs hématopoïétiques et son utilisation
US10603359B2 (en) 2014-10-30 2020-03-31 Acceleron Pharma Inc. Methods and compositions using GDF15 polypeptides for increasing red blood cells

Also Published As

Publication number Publication date
WO2000011168A3 (fr) 2000-06-22
JP2002523044A (ja) 2002-07-30
EP1105482A2 (fr) 2001-06-13
WO2000011168A2 (fr) 2000-03-02
AU5780999A (en) 2000-03-14

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Legal Events

Date Code Title Description
FZDE Discontinued