CA2360084A1 - Composes immunogeniques - Google Patents
Composes immunogeniques Download PDFInfo
- Publication number
- CA2360084A1 CA2360084A1 CA002360084A CA2360084A CA2360084A1 CA 2360084 A1 CA2360084 A1 CA 2360084A1 CA 002360084 A CA002360084 A CA 002360084A CA 2360084 A CA2360084 A CA 2360084A CA 2360084 A1 CA2360084 A1 CA 2360084A1
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- Prior art keywords
- polypeptide
- polynucleotide
- seq
- sequence
- basb058
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
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- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 1
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- 210000004698 lymphocyte Anatomy 0.000 description 1
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- 108010003700 lysyl aspartic acid Proteins 0.000 description 1
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- 101150082581 lytA gene Proteins 0.000 description 1
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- 238000004153 renaturation Methods 0.000 description 1
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- 101150055347 repA2 gene Proteins 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
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- 239000001509 sodium citrate Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
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- 230000032258 transport Effects 0.000 description 1
- 229940093609 tricaprylin Drugs 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229910021642 ultra pure water Inorganic materials 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 230000009452 underexpressoin Effects 0.000 description 1
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- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
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- 238000012800 visualization Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
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- 229940098232 yersinia enterocolitica Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention concerne des polypeptides BASB058 et des polynucléotides provenant de Neisseria Meningitidis et codant pour les polypeptides BASB058 ainsi que des procédés de fabrication de ces polypeptides par des techniques recombinantes. L'invention concerne aussi des utilisations diagnostiques, prophylactiques et thérapeutiques.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9902084.4 | 1999-01-29 | ||
| GBGB9902084.4A GB9902084D0 (en) | 1999-01-29 | 1999-01-29 | Novel compounds |
| PCT/EP2000/000560 WO2000044890A1 (fr) | 1999-01-29 | 2000-01-25 | Composes immunogeniques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2360084A1 true CA2360084A1 (fr) | 2000-08-03 |
Family
ID=10846802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002360084A Abandoned CA2360084A1 (fr) | 1999-01-29 | 2000-01-25 | Composes immunogeniques |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1153126A1 (fr) |
| AU (1) | AU2544300A (fr) |
| CA (1) | CA2360084A1 (fr) |
| GB (1) | GB9902084D0 (fr) |
| WO (1) | WO2000044890A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2261338A3 (fr) * | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Antigènes de Neisseria meningitidis et compositions |
| JP2004508801A (ja) | 1999-10-29 | 2004-03-25 | カイロン ソチエタ ア レスポンサビリタ リミタータ | ナイセリア抗原性ペプチド |
| NZ521531A (en) | 2000-02-28 | 2005-12-23 | Chiron S | Heterologous expression of neisserial proteins |
| MX339524B (es) * | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| DE602004013752D1 (de) * | 2004-06-29 | 2008-06-26 | Ct For Disease Control Dept Of | Oberflächenprotein aus Neisserien |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| CN107913396B (zh) | 2010-08-23 | 2022-03-08 | 惠氏有限责任公司 | 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂 |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| EP3299467B1 (fr) | 2012-02-02 | 2021-08-11 | GlaxoSmithKline Biologicals SA | Promoteurs pour une expression protéique accrue dans les méningocoques |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MY198910A (en) | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| WO2014136064A2 (fr) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Polypeptides immunogènes de fusion |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| WO2016132294A1 (fr) | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Compositions de neisseria meningitidis et méthodes associées |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| WO2021059181A1 (fr) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Compositions de neisseria meningitidis et méthodes associées |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2739624B1 (fr) * | 1995-10-10 | 1997-12-05 | Pasteur Merieux Serums Vacc | Nouvelle sous-unite tbp2 de neisseria meningitidis |
| WO1998017805A2 (fr) * | 1996-10-24 | 1998-04-30 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, c/o Centers for Disease Control and Prevention, Technology Transfer Office | Genes provenant du serogroupe b de neisseria meningitidis associes a une invasion |
| US6403306B1 (en) * | 1997-04-09 | 2002-06-11 | Emory University | Serogroup-specific nucleotide sequences in the molecular typing of bacterial isolates and the preparation of vaccines thereto |
| EP2261338A3 (fr) * | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Antigènes de Neisseria meningitidis et compositions |
-
1999
- 1999-01-29 GB GBGB9902084.4A patent/GB9902084D0/en not_active Ceased
-
2000
- 2000-01-25 EP EP00903629A patent/EP1153126A1/fr not_active Withdrawn
- 2000-01-25 AU AU25443/00A patent/AU2544300A/en not_active Abandoned
- 2000-01-25 WO PCT/EP2000/000560 patent/WO2000044890A1/fr not_active Ceased
- 2000-01-25 CA CA002360084A patent/CA2360084A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2544300A (en) | 2000-08-18 |
| EP1153126A1 (fr) | 2001-11-14 |
| GB9902084D0 (en) | 1999-03-24 |
| WO2000044890A1 (fr) | 2000-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |