CA2360932A1 - Detection par resonance plasmonique de surface - Google Patents

Detection par resonance plasmonique de surface Download PDF

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Publication number
CA2360932A1
CA2360932A1 CA002360932A CA2360932A CA2360932A1 CA 2360932 A1 CA2360932 A1 CA 2360932A1 CA 002360932 A CA002360932 A CA 002360932A CA 2360932 A CA2360932 A CA 2360932A CA 2360932 A1 CA2360932 A1 CA 2360932A1
Authority
CA
Canada
Prior art keywords
optical
light beam
plasmon resonance
exterior surface
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002360932A
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English (en)
Inventor
Carsten Thirstrup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vir AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2360932A1 publication Critical patent/CA2360932A1/fr
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention concerne des détecteurs à résonance plasmonique de surface (SPR) comprenant une puce de détection constituée de réseaux intégrés latéralement d'unités de puce de détection plates et un transducteur optique constitué de réseaux intégrés latéralement d'unités de transduction optique plate. Une distance sépare la puce de détection remplaçable du transducteur optique, espace prévu pour y intercaler des interconnexions optiques perpendiculaires. Des éléments optiques de focalisation et de collimation ainsi que des zones de détection sont intégrés sur la même puce de détection tandis que les interconnexions optiques sont basées sur des faisceaux lumineux collimatés qui incident de manière perpendiculaire aux interfaces. Les éléments optiques de focalisation allient un élément optique diffracteur réfléchissant sur la surface supérieure et un miroir plat facultatif sur la surface arrière des unités de puce de détection.
CA002360932A 1999-02-01 2000-01-28 Detection par resonance plasmonique de surface Abandoned CA2360932A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11811199P 1999-02-01 1999-02-01
DKPA199900118 1999-02-01
US60/118,111 1999-02-01
DKPA199900118 1999-02-01
PCT/DK2000/000036 WO2000046589A1 (fr) 1999-02-01 2000-01-28 Detection par resonance plasmonique de surface

Publications (1)

Publication Number Publication Date
CA2360932A1 true CA2360932A1 (fr) 2000-08-10

Family

ID=26063351

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002360932A Abandoned CA2360932A1 (fr) 1999-02-01 2000-01-28 Detection par resonance plasmonique de surface

Country Status (8)

Country Link
EP (1) EP1157266A1 (fr)
JP (1) JP2002536638A (fr)
KR (1) KR20010110428A (fr)
CN (1) CN1344366A (fr)
AU (1) AU771594B2 (fr)
CA (1) CA2360932A1 (fr)
NZ (1) NZ513843A (fr)
WO (1) WO2000046589A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103712954A (zh) * 2013-12-27 2014-04-09 中国科学院苏州生物医学工程技术研究所 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002008800A2 (fr) 2000-07-21 2002-01-31 Vir A/S Elements de couplage pour capteurs a resonance du plasmon de surface
JP2002296176A (ja) * 2001-01-25 2002-10-09 Fuji Photo Film Co Ltd 全反射減衰を利用したセンサー
CN1509210A (zh) * 2001-02-16 2004-06-30 维尔有限公司 光(生物)化学传感器装置的制备方法
JP3945636B2 (ja) * 2001-03-27 2007-07-18 富士フイルム株式会社 測定装置
DE10151312C2 (de) * 2001-10-17 2003-08-28 Vir As Taastrup Oberflächenplasmonen-Resonanz-Sensor
NL1019317C2 (nl) * 2001-11-06 2003-05-07 Tno Detectie van een geladen deeltje.
DE10163657B4 (de) 2001-12-21 2008-05-08 Gedig, Erk, Dr. Vorrichtung und Verfahren zur Untersuchung dünner Schichten
EP1509760A1 (fr) 2002-05-31 2005-03-02 Gyros AB Agencement detecteur utilisant une resonance plasmonique de surface
AU2003280323A1 (en) * 2002-11-18 2004-06-15 Vir A/S Dispersion compensating biosensor
NL1022916C2 (nl) * 2003-03-13 2004-09-14 Ssens B V Toestel en werkwijze voor onderzoek van een dunne laag opbouw gebruik makend van oppervlakte plasmon resonantie en inrichting en werkwijze voor het regelen van temperatuur.
US7994877B1 (en) 2008-11-10 2011-08-09 Hrl Laboratories, Llc MEMS-based quartz hybrid filters and a method of making the same
DE10324973B4 (de) * 2003-05-27 2006-04-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anordnung und Verfahren zur optischen Detektion von in Proben enthaltenen chemischen, biochemischen Molekülen und/oder Partikeln
US7002688B2 (en) * 2003-10-16 2006-02-21 Pria Diagnostics, Inc. Multilens optical assembly for a diagnostic device
JP2007514922A (ja) 2003-11-19 2007-06-07 ビーナー オーワイ 表面プラズモン共鳴測定を実施するための方法及び装置
WO2005064317A1 (fr) * 2003-12-26 2005-07-14 Matsushita Electric Industrial Co., Ltd. Procede d'analyse d'un ligand dans un echantillon et appareil d'analyse d'un ligand dans un echantillon
WO2006030957A1 (fr) 2004-09-16 2006-03-23 Canon Kabushiki Kaisha Dispositif et procede pour acquerir des informations sur la substance d'un objectif a detecter en captant une variation des caracteristiques de longueur d'onde sur la transmittance optique
JP2006171479A (ja) * 2004-12-17 2006-06-29 Ricoh Co Ltd 変換素子
CN100520394C (zh) * 2005-03-08 2009-07-29 中国科学院电子学研究所 一种单通道多参数表面等离子体谐振测试仪
JP4481967B2 (ja) * 2005-09-05 2010-06-16 キヤノン株式会社 センサ装置
JP2007101241A (ja) * 2005-09-30 2007-04-19 Fujifilm Corp センシング装置
JP4893032B2 (ja) 2006-03-15 2012-03-07 オムロン株式会社 光学部品、光学センサ及び表面プラズモンセンサ
US7592826B1 (en) * 2006-05-31 2009-09-22 Lockheed Martin Corporation Method and apparatus for detecting EM energy using surface plasmon polaritons
PT103606B (pt) * 2006-11-15 2009-03-16 Biosurfit Sa Dispositivo de detecção dinâmico baseado no efeito de ressonância de plasmão de superfície
US7884930B2 (en) 2007-06-14 2011-02-08 Hrl Laboratories, Llc Integrated quartz biological sensor and method
US20100020311A1 (en) * 2007-06-14 2010-01-28 Hrl Laboratories, Llc Integrated quartz biological sensor and method
TW200902954A (en) * 2007-07-13 2009-01-16 Univ Nat Taiwan Miniaturized surface plasmon resonance sensing chip
US10266398B1 (en) 2007-07-25 2019-04-23 Hrl Laboratories, Llc ALD metal coatings for high Q MEMS structures
DE102007036492B4 (de) * 2007-08-01 2009-07-30 Trw Automotive Electronics & Components Gmbh & Co. Kg Optische Sensorvorrichtung
JP5107003B2 (ja) * 2007-11-22 2012-12-26 パナソニックヘルスケア株式会社 エバネッセント波発生装置及びそれを用いた観察装置
JP2010025580A (ja) * 2008-07-15 2010-02-04 Olympus Corp 光学ユニット
GB0919742D0 (en) * 2009-11-11 2009-12-30 Millipore Corp Optical sensor
US8912711B1 (en) 2010-06-22 2014-12-16 Hrl Laboratories, Llc Thermal stress resistant resonator, and a method for fabricating same
US10768108B2 (en) 2011-09-28 2020-09-08 Ge Healthcare Bio-Sciences Ab Surface plasmon resonance biosensor system
KR102102934B1 (ko) 2013-12-10 2020-04-21 일루미나, 인코포레이티드 생물학적 또는 화학적 분석을 위한 바이오센서들 및 이를 제조하기 위한 방법
JP6313054B2 (ja) * 2014-01-29 2018-04-18 京セラ株式会社 光センサモジュールおよび光センサ装置
US9977097B1 (en) 2014-02-21 2018-05-22 Hrl Laboratories, Llc Micro-scale piezoelectric resonating magnetometer
US9991863B1 (en) 2014-04-08 2018-06-05 Hrl Laboratories, Llc Rounded and curved integrated tethers for quartz resonators
US10308505B1 (en) 2014-08-11 2019-06-04 Hrl Laboratories, Llc Method and apparatus for the monolithic encapsulation of a micro-scale inertial navigation sensor suite
US10031191B1 (en) 2015-01-16 2018-07-24 Hrl Laboratories, Llc Piezoelectric magnetometer capable of sensing a magnetic field in multiple vectors
JP6458056B2 (ja) * 2015-01-26 2019-01-23 株式会社日立ハイテクノロジーズ 光学的分析装置
JP6538844B2 (ja) 2015-07-07 2019-07-03 古野電気株式会社 検体測定用チップ、検体測定装置、および検体測定方法
US10110198B1 (en) 2015-12-17 2018-10-23 Hrl Laboratories, Llc Integrated quartz MEMS tuning fork resonator/oscillator
US10175307B1 (en) 2016-01-15 2019-01-08 Hrl Laboratories, Llc FM demodulation system for quartz MEMS magnetometer
CN111366998B (zh) * 2020-03-16 2022-04-01 国家纳米科学中心 一种等离子体激元激子杂化结构及其制备方法和应用
GB202010010D0 (en) * 2020-06-30 2020-08-12 Ams Int Ag Imaging surface plasmon resonance apparatus
US11486825B1 (en) * 2022-06-07 2022-11-01 The Florida International University Board Of Trustees Devices and methods for analysis of biological matter using plasmon resonance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
WO1997015819A1 (fr) * 1995-10-25 1997-05-01 University Of Washington Capteur a conducteur de lumiere, a plasmon en surface
EP0797091A1 (fr) * 1996-03-19 1997-09-24 Texas Instruments Incorporated Capteur à resonance de plasmon de surface avec element optique remplacable
DE69830529T2 (de) * 1997-02-07 2006-05-11 Fuji Photo Film Co., Ltd., Minami-Ashigara Oberflächen-Plasmonen-Sensor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103712954A (zh) * 2013-12-27 2014-04-09 中国科学院苏州生物医学工程技术研究所 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法
CN103712954B (zh) * 2013-12-27 2016-02-03 中国科学院苏州生物医学工程技术研究所 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法

Also Published As

Publication number Publication date
WO2000046589A1 (fr) 2000-08-10
EP1157266A1 (fr) 2001-11-28
CN1344366A (zh) 2002-04-10
NZ513843A (en) 2002-07-26
AU771594B2 (en) 2004-03-25
KR20010110428A (ko) 2001-12-13
JP2002536638A (ja) 2002-10-29
AU2278500A (en) 2000-08-25

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20060130