CA2364012A1 - Systeme de transfert de liquides et procede associe - Google Patents
Systeme de transfert de liquides et procede associe Download PDFInfo
- Publication number
- CA2364012A1 CA2364012A1 CA002364012A CA2364012A CA2364012A1 CA 2364012 A1 CA2364012 A1 CA 2364012A1 CA 002364012 A CA002364012 A CA 002364012A CA 2364012 A CA2364012 A CA 2364012A CA 2364012 A1 CA2364012 A1 CA 2364012A1
- Authority
- CA
- Canada
- Prior art keywords
- plunger
- syringe
- needle
- liquid
- assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 126
- 239000011248 coating agent Substances 0.000 claims description 23
- 238000000576 coating method Methods 0.000 claims description 23
- 238000000429 assembly Methods 0.000 claims description 19
- 230000000712 assembly Effects 0.000 claims description 19
- 230000002209 hydrophobic effect Effects 0.000 claims description 14
- 230000007246 mechanism Effects 0.000 claims description 6
- 238000012546 transfer Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 5
- 229920001296 polysiloxane Polymers 0.000 claims description 4
- 230000000977 initiatory effect Effects 0.000 claims 1
- 229910001220 stainless steel Inorganic materials 0.000 description 7
- 239000010935 stainless steel Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 6
- 238000010276 construction Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000036316 preload Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 241000243251 Hydra Species 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000009432 framing Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- QRXWMOHMRWLFEY-UHFFFAOYSA-N isoniazide Chemical compound NNC(=O)C1=CC=NC=C1 QRXWMOHMRWLFEY-UHFFFAOYSA-N 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00373—Hollow needles
- B01J2219/00376—Hollow needles in multiple or parallel arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
L'invention porte sur des systèmes et procédés de transfert de liquides dont l'un comporte une base (12) et au moins 864 pipettes fonctionnellement reliées à la base (12). Chacune des pipettes comporte un embout distal pouvant aspirer ou éjecter un volume sensiblement égal de liquide. De plus, les embouts sont disposés à l'intérieur d'une surface de moins de 80 cm?2¿.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26036899A | 1999-03-01 | 1999-03-01 | |
| US09/260,368 | 1999-03-01 | ||
| PCT/US2000/004836 WO2000051735A1 (fr) | 1999-03-01 | 2000-02-25 | Systeme de transfert de liquides et procede associe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2364012A1 true CA2364012A1 (fr) | 2000-09-08 |
Family
ID=22988885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002364012A Abandoned CA2364012A1 (fr) | 1999-03-01 | 2000-02-25 | Systeme de transfert de liquides et procede associe |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1165234A1 (fr) |
| JP (1) | JP2002537978A (fr) |
| AU (1) | AU3378600A (fr) |
| CA (1) | CA2364012A1 (fr) |
| WO (1) | WO2000051735A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6893877B2 (en) | 1998-01-12 | 2005-05-17 | Massachusetts Institute Of Technology | Methods for screening substances in a microwell array |
| AU756982B2 (en) | 1999-03-19 | 2003-01-30 | Life Technologies Corporation | Multi-through hole testing plate for high throughput screening |
| US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
| JP4361271B2 (ja) | 2000-10-10 | 2009-11-11 | バイオトローブ・インコーポレイテツド | アッセイ、合成、および保存用の器具、ならびに、その作製、使用、および操作の方法 |
| US20100261159A1 (en) | 2000-10-10 | 2010-10-14 | Robert Hess | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
| AU2003302264A1 (en) | 2002-12-20 | 2004-09-09 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
| EP1735097B1 (fr) | 2004-03-12 | 2016-11-30 | Life Technologies Corporation | Chargement d'ensembles d'echantillons de l'ordre du nanolitre |
| US12070731B2 (en) | 2004-08-04 | 2024-08-27 | Life Technologies Corporation | Methods and systems for aligning dispensing arrays with microfluidic sample arrays |
| US20060105453A1 (en) | 2004-09-09 | 2006-05-18 | Brenan Colin J | Coating process for microfluidic sample arrays |
| CN103920425B (zh) * | 2014-04-28 | 2016-03-02 | 四川沃文特生物技术有限公司 | 保证试剂加注准确性的系统 |
| CN103920426B (zh) * | 2014-04-28 | 2016-01-20 | 四川沃文特生物技术有限公司 | 对试剂管加注药液的装置 |
| US20160346783A1 (en) * | 2015-05-28 | 2016-12-01 | Mo Bio Laboratories, Inc. | Adjustable device for multi-channel pipette |
| WO2017119097A1 (fr) * | 2016-01-07 | 2017-07-13 | 株式会社 エー・アンド・デイ | Pipette multicanal |
| WO2018075577A1 (fr) * | 2016-10-18 | 2018-04-26 | President And Fellows Of Harvard College | Procédés de traitement microfluidique intégré pour empêcher une perte d'échantillon |
| US20240173712A1 (en) * | 2022-11-29 | 2024-05-30 | Takara Bio Usa, Inc. | Device for Liquid Handling |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4555957A (en) * | 1983-10-14 | 1985-12-03 | Cetus Corporation | Bi-directional liquid sample handling system |
| US4554839A (en) * | 1983-10-14 | 1985-11-26 | Cetus Corporation | Multiple trough vessel for automated liquid handling apparatus |
| DE3410508C2 (de) * | 1984-03-22 | 1986-06-26 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Serien-Abfüllgerät zum Befüllen der Becher einer Mikrobecherplatte |
| US4952518A (en) * | 1984-10-01 | 1990-08-28 | Cetus Corporation | Automated assay machine and assay tray |
| US4586546A (en) * | 1984-10-23 | 1986-05-06 | Cetus Corporation | Liquid handling device and method |
| US5226462A (en) * | 1991-07-26 | 1993-07-13 | Carl Richard A | Introducing measured amounts of liquid into receptacles |
| US5849598A (en) * | 1996-03-15 | 1998-12-15 | Washington University | Method for transferring micro quantities of liquid samples to discrete locations |
| US5733509A (en) * | 1996-04-17 | 1998-03-31 | Motorola, Inc. | Method and system for synthesizing oligonucleotides using nucleotide-specific dispensing bars |
| US5853894A (en) * | 1997-02-03 | 1998-12-29 | Cytonix Corporation | Laboratory vessel having hydrophobic coating and process for manufacturing same |
-
2000
- 2000-02-25 EP EP00911980A patent/EP1165234A1/fr not_active Withdrawn
- 2000-02-25 JP JP2000602394A patent/JP2002537978A/ja not_active Withdrawn
- 2000-02-25 AU AU33786/00A patent/AU3378600A/en not_active Abandoned
- 2000-02-25 WO PCT/US2000/004836 patent/WO2000051735A1/fr not_active Ceased
- 2000-02-25 CA CA002364012A patent/CA2364012A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU3378600A (en) | 2000-09-21 |
| JP2002537978A (ja) | 2002-11-12 |
| WO2000051735A1 (fr) | 2000-09-08 |
| EP1165234A1 (fr) | 2002-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |