CA2366059A1 - Clonage d'adn complementaire de 5, 8, 9 et 11 de mage et leur utilisation dans le diagnostic du cancer - Google Patents

Clonage d'adn complementaire de 5, 8, 9 et 11 de mage et leur utilisation dans le diagnostic du cancer Download PDF

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Publication number
CA2366059A1
CA2366059A1 CA002366059A CA2366059A CA2366059A1 CA 2366059 A1 CA2366059 A1 CA 2366059A1 CA 002366059 A CA002366059 A CA 002366059A CA 2366059 A CA2366059 A CA 2366059A CA 2366059 A1 CA2366059 A1 CA 2366059A1
Authority
CA
Canada
Prior art keywords
mage
glu
seq
leu
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002366059A
Other languages
English (en)
Inventor
Alfonso Serrano
Bernard Lethe
Christophe Lurquin
Etienne De Plaen
Donata Rimoldi
Thierry Boon-Falleur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Ludwig Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Cancer Research filed Critical Ludwig Cancer Research
Publication of CA2366059A1 publication Critical patent/CA2366059A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des molécules d'ADN complémentaire isolées et déterminées grâce à une méthode élaborée pour faciliter le niveau d'expression génique. L'invention concerne également des protéines et des peptides obtenus sur la base de ces molécules d'ADN complémentaire, ainsi que différentes utilisations diagnostiques et thérapeutiques de ces matières.
CA002366059A 1999-03-02 2000-03-01 Clonage d'adn complementaire de 5, 8, 9 et 11 de mage et leur utilisation dans le diagnostic du cancer Abandoned CA2366059A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26097899A 1999-03-02 1999-03-02
US09/260,978 1999-03-02
PCT/US2000/005346 WO2000052163A1 (fr) 1999-03-02 2000-03-01 Clonage d'adn complementaire de 5, 8, 9 et 11 de mage et leur utilisation dans le diagnostic du cancer

Publications (1)

Publication Number Publication Date
CA2366059A1 true CA2366059A1 (fr) 2000-09-08

Family

ID=22991462

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002366059A Abandoned CA2366059A1 (fr) 1999-03-02 2000-03-01 Clonage d'adn complementaire de 5, 8, 9 et 11 de mage et leur utilisation dans le diagnostic du cancer

Country Status (7)

Country Link
EP (1) EP1194542A1 (fr)
JP (1) JP2003512814A (fr)
KR (1) KR20020011967A (fr)
AU (1) AU3389500A (fr)
CA (1) CA2366059A1 (fr)
NZ (1) NZ513739A (fr)
WO (1) WO2000052163A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE545708T1 (de) * 2005-11-14 2012-03-15 Univ Laval Krebsantigen mage-a9 und verwendungen davon
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
WO2019007974A1 (fr) 2017-07-07 2019-01-10 Immatics Biotechnologies Gmbh Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie du cancer du poumon, y compris le cpnpc, le cppc et d'autres cancers
KR20200026898A (ko) 2017-07-07 2020-03-11 이매틱스 바이오테크놀로지스 게엠베하 Nsclc, sclc 등 폐암 및 기타 암에 대한 면역요법에서의 사용을 위한 신규 펩티드 및 펩티드의 조합
FR3087448B1 (fr) 2018-10-23 2023-10-13 Pdc Line Pharma Lignee pdc modifiee pour secreter une cytokine
TW202039535A (zh) 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 B*08限制肽和肽組合物抗癌免疫治療和相關方法
WO2025242815A1 (fr) * 2024-05-23 2025-11-27 CureVac SE Immunothérapie d'un carcinome à cellules squameuses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342774A (en) * 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5612201A (en) * 1991-05-23 1997-03-18 Ludwig Institute For Cancer Research Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor

Also Published As

Publication number Publication date
NZ513739A (en) 2001-09-28
KR20020011967A (ko) 2002-02-09
AU3389500A (en) 2000-09-21
JP2003512814A (ja) 2003-04-08
WO2000052163A1 (fr) 2000-09-08
EP1194542A1 (fr) 2002-04-10

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