CA2369910A1 - Compositions et procedes pour traiter des maladies hyperproliferatives - Google Patents

Compositions et procedes pour traiter des maladies hyperproliferatives Download PDF

Info

Publication number
CA2369910A1
CA2369910A1 CA002369910A CA2369910A CA2369910A1 CA 2369910 A1 CA2369910 A1 CA 2369910A1 CA 002369910 A CA002369910 A CA 002369910A CA 2369910 A CA2369910 A CA 2369910A CA 2369910 A1 CA2369910 A1 CA 2369910A1
Authority
CA
Canada
Prior art keywords
agonist
rxr
rar
compound
camp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002369910A
Other languages
English (en)
Inventor
Gerard BENOIT
Hinrich Gronemeyer
Michel Lanotte
Marco Gottardis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Universite de Strasbourg
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Sante et de la Recherche Medicale INSERM, Universite de Strasbourg, Bristol Myers Squibb Co filed Critical Centre National de la Recherche Scientifique CNRS
Publication of CA2369910A1 publication Critical patent/CA2369910A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des compositions comportant un agoniste du récepteur X des rétinoïdes et un agent capable d'activer la protéine kinase A. L'invention concerne aussi des procédés pour traiter des maladies hyperprolifératives par l'administration d'un agoniste du récepteur X des rétinoïdes et d'un agent capable d'activer la protéine kinase A.
CA002369910A 1999-04-23 1999-04-23 Compositions et procedes pour traiter des maladies hyperproliferatives Abandoned CA2369910A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/008908 WO2000064260A1 (fr) 1999-04-23 1999-04-23 Compositions et procedes pour traiter des maladies hyperproliferatives

Publications (1)

Publication Number Publication Date
CA2369910A1 true CA2369910A1 (fr) 2000-11-02

Family

ID=22272621

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002369910A Abandoned CA2369910A1 (fr) 1999-04-23 1999-04-23 Compositions et procedes pour traiter des maladies hyperproliferatives

Country Status (5)

Country Link
EP (1) EP1173061A1 (fr)
JP (1) JP2002542268A (fr)
AU (1) AU773928B2 (fr)
CA (1) CA2369910A1 (fr)
WO (1) WO2000064260A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4866201A (en) * 2000-04-13 2001-10-30 Pierre Chambon Compositions and methods for use in modulating immune system function
AU2002229611A1 (en) * 2000-12-08 2002-06-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of active compounds capable of modulating the intracellular pathway triggered by the dp receptor in langerhans cells
JP5249484B2 (ja) * 2001-12-11 2013-07-31 第一三共株式会社 医薬組成物
EP1531737B1 (fr) * 2002-08-14 2008-12-17 Boston Scientific Limited Systemes et dispositifs relatifs a la pose d'implants medicaux
AU2003270202A1 (en) * 2002-09-17 2004-04-08 Centre National De La Recherche Scientifique Pharmaceutical compositions increasing camp useful for the treatment of cancers
GB0224415D0 (en) * 2002-10-21 2002-11-27 Medical Res Council Compositions
JPWO2004056351A1 (ja) * 2002-12-20 2006-04-20 エーザイ株式会社 Ｐｋａ活性調節剤
US10328040B2 (en) 2014-01-17 2019-06-25 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic methods
US10238626B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
US10238655B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Dihydroindene and tetrahydronaphthalene compounds
US10231947B2 (en) 2017-01-23 2019-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Isochroman compounds and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US5399586A (en) * 1993-03-11 1995-03-21 Allergan, Inc. Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity
AU4676999A (en) * 1998-06-12 1999-12-30 Ligand Pharmaceuticals, Inc. Treatment of anti-estrogen resistant breast cancer using rxr modulators

Also Published As

Publication number Publication date
JP2002542268A (ja) 2002-12-10
WO2000064260A1 (fr) 2000-11-02
AU773928B2 (en) 2004-06-10
AU4181599A (en) 2000-11-10
EP1173061A1 (fr) 2002-01-23

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued