CA2376479A1 - Peptides retro-inverses derives de l'interleukine 6 - Google Patents
Peptides retro-inverses derives de l'interleukine 6 Download PDFInfo
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- CA2376479A1 CA2376479A1 CA002376479A CA2376479A CA2376479A1 CA 2376479 A1 CA2376479 A1 CA 2376479A1 CA 002376479 A CA002376479 A CA 002376479A CA 2376479 A CA2376479 A CA 2376479A CA 2376479 A1 CA2376479 A1 CA 2376479A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Ces peptides rétro-inverses dérivés de l'interleukine 6 (IL-6) possèdent entre 17 et 40 acides aminés environ et renferment la séquence illustrée par SEQ ID N·: 1. Ces peptides, qui ont la même activité que l'IL-6 endogène, ont également une activité neurotrophique. La présence de la liaison génétique aminoacide de type D dans ces peptides les rend moins sujets à un dégradation protéolytique <i>in vivo</i>.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13968799P | 1999-06-16 | 1999-06-16 | |
| US60/139,687 | 1999-06-16 | ||
| PCT/US2000/040227 WO2000077033A1 (fr) | 1999-06-16 | 2000-06-16 | Peptides rétro-inverses dérivés de l'interleukine 6 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2376479A1 true CA2376479A1 (fr) | 2000-12-21 |
Family
ID=22487847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002376479A Abandoned CA2376479A1 (fr) | 1999-06-16 | 2000-06-16 | Peptides retro-inverses derives de l'interleukine 6 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1183267A4 (fr) |
| JP (1) | JP4786843B2 (fr) |
| AU (1) | AU6540500A (fr) |
| CA (1) | CA2376479A1 (fr) |
| IL (3) | IL147094A0 (fr) |
| WO (1) | WO2000077033A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571787A (en) | 1993-07-30 | 1996-11-05 | Myelos Corporation | Prosaposin as a neurotrophic factor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
| US6271196B1 (en) * | 1996-03-05 | 2001-08-07 | Regents Of The University Of Ca | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
| WO1998039357A1 (fr) * | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Procedes pour soulager les douleurs neuropathiques |
| US6458357B1 (en) * | 1997-09-09 | 2002-10-01 | Myelos Corporation | Retro-inverso neurotrophic and analgesic peptides |
-
2000
- 2000-06-16 CA CA002376479A patent/CA2376479A1/fr not_active Abandoned
- 2000-06-16 IL IL14709400A patent/IL147094A0/xx unknown
- 2000-06-16 WO PCT/US2000/040227 patent/WO2000077033A1/fr not_active Ceased
- 2000-06-16 AU AU65405/00A patent/AU6540500A/en not_active Abandoned
- 2000-06-16 JP JP2001503890A patent/JP4786843B2/ja not_active Expired - Fee Related
- 2000-06-16 EP EP00952761A patent/EP1183267A4/fr not_active Withdrawn
-
2001
- 2001-12-13 IL IL147094A patent/IL147094A/en not_active IP Right Cessation
-
2008
- 2008-03-09 IL IL190034A patent/IL190034A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003502343A (ja) | 2003-01-21 |
| IL147094A0 (en) | 2002-08-14 |
| EP1183267A4 (fr) | 2002-09-18 |
| JP4786843B2 (ja) | 2011-10-05 |
| IL147094A (en) | 2011-04-28 |
| WO2000077033A1 (fr) | 2000-12-21 |
| EP1183267A1 (fr) | 2002-03-06 |
| IL190034A0 (en) | 2011-08-01 |
| AU6540500A (en) | 2001-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |