CA2377434A1 - Induction d'agent therapeutique en reponse a un stress et procedes correspondant - Google Patents

Induction d'agent therapeutique en reponse a un stress et procedes correspondant Download PDF

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Publication number
CA2377434A1
CA2377434A1 CA002377434A CA2377434A CA2377434A1 CA 2377434 A1 CA2377434 A1 CA 2377434A1 CA 002377434 A CA002377434 A CA 002377434A CA 2377434 A CA2377434 A CA 2377434A CA 2377434 A1 CA2377434 A1 CA 2377434A1
Authority
CA
Canada
Prior art keywords
nucleic acid
sequence
acid construct
cell
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002377434A
Other languages
English (en)
Inventor
Amy S. Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2377434A1 publication Critical patent/CA2377434A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des compositions et des procédés destinés à l'expression sélective d'une séquence d'acide nucléique hétérologue dans un tissu cible, et concerne plus particulièrement le promoteur de réaction au stress de la grp 78 (glucose regulated protein), et son utilisation en thérapie génique et dans la production d'animaux transgéniques.
CA002377434A 1999-06-28 2000-06-28 Induction d'agent therapeutique en reponse a un stress et procedes correspondant Abandoned CA2377434A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14150599P 1999-06-28 1999-06-28
US60/141,505 1999-06-28
PCT/US2000/017885 WO2001000791A1 (fr) 1999-06-28 2000-06-28 Induction d'agent therapeutique en reponse a un stress et procedes correspondant

Publications (1)

Publication Number Publication Date
CA2377434A1 true CA2377434A1 (fr) 2001-01-04

Family

ID=22495982

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002377434A Abandoned CA2377434A1 (fr) 1999-06-28 2000-06-28 Induction d'agent therapeutique en reponse a un stress et procedes correspondant

Country Status (5)

Country Link
EP (1) EP1194527A4 (fr)
AU (1) AU6201500A (fr)
CA (1) CA2377434A1 (fr)
HK (1) HK1044568A1 (fr)
WO (1) WO2001000791A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3158514A1 (fr) * 2024-01-23 2025-07-25 Asfalia Biologics Système de régulation de l’expression d’un transgène d’intérêt

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656732B1 (en) 2001-05-18 2003-12-02 Isis Pharmaceuticals, Inc. Antisense inhibition of src-c expression
EP1678301B1 (fr) * 2003-09-08 2009-12-09 The University of Queensland Systeme d'expression bacterien inductible utilisant un promoteur sspa de la salmonelle

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0680517T4 (da) * 1993-01-21 2005-05-02 Harvard College Fremgangsmåde og diagnostiske sæt til bestemmelse af en forbindelses toksicitet under anvendelse afstress-promotorer fra pattedyr

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3158514A1 (fr) * 2024-01-23 2025-07-25 Asfalia Biologics Système de régulation de l’expression d’un transgène d’intérêt
WO2025157812A1 (fr) * 2024-01-23 2025-07-31 Asfalia Biologics Système de régulation de l'expression d'un transgène d'intérêt

Also Published As

Publication number Publication date
EP1194527A1 (fr) 2002-04-10
AU6201500A (en) 2001-01-31
HK1044568A1 (zh) 2002-10-25
WO2001000791A9 (fr) 2002-07-25
WO2001000791A1 (fr) 2001-01-04
EP1194527A4 (fr) 2004-04-14

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