CA2386509A1 - Recepteurs couples par des proteines g exprimes dans le cerveau - Google Patents

Recepteurs couples par des proteines g exprimes dans le cerveau Download PDF

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Publication number
CA2386509A1
CA2386509A1 CA002386509A CA2386509A CA2386509A1 CA 2386509 A1 CA2386509 A1 CA 2386509A1 CA 002386509 A CA002386509 A CA 002386509A CA 2386509 A CA2386509 A CA 2386509A CA 2386509 A1 CA2386509 A1 CA 2386509A1
Authority
CA
Canada
Prior art keywords
transmembrane receptor
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002386509A
Other languages
English (en)
Inventor
Gabriel Vogeli
Linda S. Wood
Kalpana Merchant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2386509A1 publication Critical patent/CA2386509A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des gènes codant des récepteurs couplés par des protéines G jusqu'ici inconnus, des constructions et des cellules hôtes recombinées incorporant les gènes; les polypeptides GPCR codés par les gènes; des anticorps dirigés contre les polypeptides; et des méthodes de production et d'utilisation de tout ce qui est précité.
CA002386509A 1999-10-27 2000-10-27 Recepteurs couples par des proteines g exprimes dans le cerveau Abandoned CA2386509A1 (fr)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US42765399A 1999-10-27 1999-10-27
US42802099A 1999-10-27 1999-10-27
US42785999A 1999-10-27 1999-10-27
US42811499A 1999-10-27 1999-10-27
US09/427,653 1999-10-27
US09/427,859 1999-10-27
US09/428,114 1999-10-27
US09/428,020 1999-10-27
US42969599A 1999-10-28 1999-10-28
US42967699A 1999-10-28 1999-10-28
US42955599A 1999-10-28 1999-10-28
US42951799A 1999-10-28 1999-10-28
US09/429,517 1999-10-28
US09/429,676 1999-10-28
US09/429,695 1999-10-28
US09/429,555 1999-10-28
US45439999A 1999-12-03 1999-12-03
US09/454,399 1999-12-03
US48179400A 2000-01-12 2000-01-12
US09/481,794 2000-01-12
PCT/US2000/029601 WO2001031014A2 (fr) 1999-10-27 2000-10-27 Recepteurs couples par des proteines g exprimes dans le cerveau

Publications (1)

Publication Number Publication Date
CA2386509A1 true CA2386509A1 (fr) 2001-05-03

Family

ID=27581260

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386509A Abandoned CA2386509A1 (fr) 1999-10-27 2000-10-27 Recepteurs couples par des proteines g exprimes dans le cerveau

Country Status (4)

Country Link
EP (1) EP1230361A2 (fr)
AU (1) AU1575601A (fr)
CA (1) CA2386509A1 (fr)
WO (1) WO2001031014A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555339B1 (en) 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US7119190B2 (en) 1997-04-14 2006-10-10 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human G protein-coupled receptors
EP1157038A4 (fr) * 1999-02-26 2005-01-19 Smithkline Beecham Corp Clonage du recepteur 7tm (axor 17) du type p2y
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
CN1310945C (zh) * 1999-11-17 2007-04-18 阿瑞那制药公司 人g蛋白偶联受体的内源形式和非内源形式
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
AU2001269014A1 (en) * 2000-05-18 2001-11-26 Bayer Aktiengesellschaft Regulation of human follicle stimulating hormone-like g protein-coupled receptor
WO2001087937A2 (fr) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. Recepteurs couples aux proteines g
AU6604901A (en) * 2000-06-05 2001-12-17 Bayer Aktiengesellschaft Regulation of human hm74-like g protein coupled receptor
US20030212255A1 (en) * 2000-07-26 2003-11-13 Muralidhara Padigaru Novel proteins and nucleic acids encoding same
EP1404716A2 (fr) * 2001-06-26 2004-04-07 Novartis AG Nouveaux recepteurs couples a la proteine g et leurs sequences d'adn
US6902902B2 (en) 2001-11-27 2005-06-07 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
AU2002359729A1 (en) * 2001-12-20 2003-07-09 Aventis Pharmaceuticals Inc. Novel g proein-coupled receptor, gave7
JP2005514934A (ja) * 2002-01-23 2005-05-26 アベンティス・ファーマスーティカルズ・インコーポレイテツド Ｇタンパク質共役受容体をコードする核酸、およびその使用
US7527935B2 (en) 2002-03-19 2009-05-05 Mitsubishi Tanabe Pharma Corporation G-protein coupled receptor having eicosanoid as ligand and gene thereof
AU2003220913A1 (en) * 2002-03-19 2003-09-29 Tanabe Seiyaku Co., Ltd. Novel g protein-coupled recepotrs and genes thereof
US20080260744A1 (en) 2002-09-09 2008-10-23 Omeros Corporation G protein coupled receptors and uses thereof
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
WO2006024449A2 (fr) * 2004-09-01 2006-03-09 Bayer Healthcare Ag Diagnostic et traitement des maladies associees au recepteur 1 de cysteinyl leucotriene (cyslt1)
WO2006040534A2 (fr) * 2004-10-11 2006-04-20 Paradigm Therapeutics Limited Methode
EP2091556B1 (fr) * 2006-11-15 2018-07-25 Omeros Corporation Modèle animal non-humain pour des maladies metaboliques comprenant une mutation dans le gène sreb2/gpr85

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955308A (en) * 1997-06-18 1999-09-21 Smithkline Beecham Corporation cDNA clone HEAOD54 that encodes a human 7-transmembrane receptor
DE69931360T2 (de) * 1998-03-12 2007-02-08 Astellas Pharma Inc. Neue, an ein g-protein gekoppelte rezeptorproteine
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
AU5801099A (en) * 1998-09-02 2000-03-21 Millennium Pharmaceuticals, Inc. 14926 receptor, a novel g-protein coupled receptor
CA2348688A1 (fr) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Recepteurs non-endogenes de la proteine g humaine ayant une activite constitutive
KR20080104062A (ko) * 1998-11-20 2008-11-28 아레나 파마슈티칼스, 인크. 사람의 오르판 ｇ 단백질 커플링 수용체
WO2001007612A2 (fr) * 1999-07-21 2001-02-01 Incyte Genomics, Inc. Recepteurs et proteines associees

Also Published As

Publication number Publication date
EP1230361A2 (fr) 2002-08-14
WO2001031014A3 (fr) 2002-06-06
WO2001031014A2 (fr) 2001-05-03
AU1575601A (en) 2001-05-08

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