CA2393646A1 - Stimulation de l'angiogenese par l'utilisation de survivine - Google Patents
Stimulation de l'angiogenese par l'utilisation de survivine Download PDFInfo
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- CA2393646A1 CA2393646A1 CA002393646A CA2393646A CA2393646A1 CA 2393646 A1 CA2393646 A1 CA 2393646A1 CA 002393646 A CA002393646 A CA 002393646A CA 2393646 A CA2393646 A CA 2393646A CA 2393646 A1 CA2393646 A1 CA 2393646A1
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- survivin
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- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 230000005747 tumor angiogenesis Effects 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 230000005751 tumor progression Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
- 229960001600 xylazine Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 230000004572 zinc-binding Effects 0.000 description 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Cette invention a trait à des techniques visant à stimuler l'angiogenèse à l'aide d'agents renforçant l'activité de la survivine, sa fonctionnalité et/ou son expression. Elle concerne également des techniques visant à inhiber l'angiogenèse à l'aide d'agents inhibant l'activité de la survivine, sa fonctionnalité et/ou son expression.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17299199P | 1999-12-21 | 1999-12-21 | |
| US60/172,991 | 1999-12-21 | ||
| PCT/US2000/034663 WO2001046455A2 (fr) | 1999-12-21 | 2000-12-21 | Stimulation de l'angiogenèse par l'utilisation de survivine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2393646A1 true CA2393646A1 (fr) | 2001-06-28 |
Family
ID=22630045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002393646A Abandoned CA2393646A1 (fr) | 1999-12-21 | 2000-12-21 | Stimulation de l'angiogenese par l'utilisation de survivine |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1242050A4 (fr) |
| JP (1) | JP2003529554A (fr) |
| AU (1) | AU2730801A (fr) |
| CA (1) | CA2393646A1 (fr) |
| MX (1) | MXPA02006167A (fr) |
| WO (1) | WO2001046455A2 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4785252B2 (ja) | 1999-02-26 | 2011-10-05 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | Ｔｒｐｍ−２アンチセンス療法 |
| US6900187B2 (en) | 1999-02-26 | 2005-05-31 | The University Of British Columbia | TRPM-2 antisense therapy using an oligonucleotide having 2′-O-(2-methoxy)ethyl modifications |
| US7569551B2 (en) | 2000-02-25 | 2009-08-04 | The University Of British Columbia | Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides |
| AU2001275707A1 (en) * | 2000-07-26 | 2002-02-05 | Cambridge University Technical Services Limited | Use of panaxatriol for stimulation angiogenesis |
| WO2003062421A1 (fr) | 2002-01-17 | 2003-07-31 | The University Of British Columbia | Oligonucleotides antisens bispecifiques qui inhibent l'igfbp-2 et l'igfbp-5 et procedes d'utilisation associes |
| SI1530636T1 (sl) | 2002-08-21 | 2010-12-31 | Stry Liaison Ofiice The University Of British Columbia Umiversity Indu | Zdravljenje melanoma z zniĹľanjem nivojev klusterina |
| US7713738B2 (en) | 2003-02-10 | 2010-05-11 | Enzon Pharmaceuticals, Inc. | Oligomeric compounds for the modulation of survivin expression |
| AU2004233043A1 (en) * | 2003-04-18 | 2004-11-04 | The Trustees Of The University Of Pennsylvania | Compositions and methods for siRNA inhibition of angiopoietin 1 and 2 and their receptor Tie2 |
| US8710020B2 (en) | 2004-04-02 | 2014-04-29 | The University Of British Columbia | Clusterin antisense therapy for treatment of cancer |
| WO2006050732A2 (fr) | 2004-11-09 | 2006-05-18 | Santaris Pharma A/S | Oligonucleotides lna et traitement du cancer |
| AU2008307145B2 (en) * | 2007-10-04 | 2014-07-10 | Bionomics Limited | Markers of endothelial cells and uses thereof |
| FR2932086A1 (fr) * | 2008-06-06 | 2009-12-11 | Lvmh Rech | Methode de soin cosmetique anti-age par stimulation de l'expression de la survivine |
| KR102095617B1 (ko) | 2013-03-15 | 2020-03-31 | 아이리스 인터내셔널 인크. | 혈액 샘플에서의 입자 분석을 위한 오토포커스 시스템 및 방법 |
| KR102773176B1 (ko) | 2015-09-04 | 2025-02-27 | 헬스 리서치 인코포레이티드 | 암 치료용 안티-서비빈 항체 |
-
2000
- 2000-12-21 CA CA002393646A patent/CA2393646A1/fr not_active Abandoned
- 2000-12-21 AU AU27308/01A patent/AU2730801A/en not_active Abandoned
- 2000-12-21 JP JP2001546951A patent/JP2003529554A/ja active Pending
- 2000-12-21 WO PCT/US2000/034663 patent/WO2001046455A2/fr not_active Ceased
- 2000-12-21 MX MXPA02006167A patent/MXPA02006167A/es unknown
- 2000-12-21 EP EP00990262A patent/EP1242050A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02006167A (es) | 2004-02-26 |
| WO2001046455A2 (fr) | 2001-06-28 |
| JP2003529554A (ja) | 2003-10-07 |
| EP1242050A4 (fr) | 2004-05-26 |
| EP1242050A2 (fr) | 2002-09-25 |
| AU2730801A (en) | 2001-07-03 |
| WO2001046455A3 (fr) | 2002-05-10 |
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