CA2396401A1 - Novel fgf homolog zfgf12 - Google Patents

Novel fgf homolog zfgf12 Download PDF

Info

Publication number: CA2396401A1
Authority: CA; Canada
Prior art keywords: residue; polypeptide; sequence; cells; amino acid
Prior art date: 2000-01-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002396401A

Other languages

English (en)

French (fr)

Inventor

Darrell C. Conklin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Zymogenetics Inc

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-05

Filing date

2001-01-04

Publication date

2001-07-12

2001-01-04 Application filed by Individual filed Critical Individual

2001-07-12 Publication of CA2396401A1 publication Critical patent/CA2396401A1/en

Status Abandoned legal-status Critical Current

Links

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230000005945 translocation Effects 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Emergency Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Obesity (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)

CA002396401A 2000-01-05 2001-01-04 Novel fgf homolog zfgf12 Abandoned CA2396401A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US47806200A	2000-01-05	2000-01-05
US09/478,062		2000-01-05
PCT/US2001/000238 WO2001049740A1 (en)	2000-01-05	2001-01-04	Novel fgf homolog zfgf12

Publications (1)

Publication Number	Publication Date
CA2396401A1 true CA2396401A1 (en)	2001-07-12

Family

ID=23898370

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002396401A Abandoned CA2396401A1 (en)	2000-01-05	2001-01-04	Novel fgf homolog zfgf12

Country Status (5)

Country	Link
EP (1)	EP1246843A1 (de)
JP (1)	JP2003518944A (de)
AU (1)	AU2759201A (de)
CA (1)	CA2396401A1 (de)
WO (1)	WO2001049740A1 (de)

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EP1947182A1 (de) *	2000-02-15	2008-07-23	Amgen Inc.	Fibroblastenwachstumsfaktor-23-Moleküle und ihre Verwendung
AU3976701A (en) *	2000-02-15	2001-08-27	Amgen, Inc.	Fibroblast growth factor-23 molecules and uses thereof
WO2001066595A2 (en) *	2000-03-08	2001-09-13	Chiron Corporation	Human fgf-23 gene and gene expression products
AU2001245535A1 (en) *	2000-03-08	2001-09-17	Chiron Corporation	Human fgf-23 gene and gene expression products
ATE461213T1 (de) *	2000-07-19	2010-04-15	Advanced Res & Tech Inst	Neuer fibroblastwachstumsfaktor (fgf23) und methoden zur verwendung
EP2233571B1 (de) *	2000-08-11	2012-11-07	Kyowa Hakko Kirin Co., Ltd.	Den Phosphorsäure-Metabolismus, den Kalzium-Metabolismus, Verkalkung und den Vitamin D-Metabolismus kontrollierende Polypeptide sowie für diese kodierende DNA-Moleküle
JP4527982B2 (ja) *	2001-12-28	2010-08-18	協和発酵キリン株式会社	線維芽細胞増殖因子−２３に対する抗体
EP1728514A1 (de) *	2005-06-03	2006-12-06	Immunotech S.A.	Verwendungen von Oligonukleotiden welche mesenchymale Stammzellen Proliferation verursachen
US7883705B2 (en)	2007-02-14	2011-02-08	Kyowa Hakko Kirin Co., Ltd.	Anti FGF23 antibody and a pharmaceutical composition comprising the same
CN105601748B (zh)	2011-07-01	2021-08-27	恩格姆生物制药公司	用于代谢病症和疾病治疗的组合物、应用和方法
HK1214832A1 (zh)	2012-11-28	2016-08-05	恩格姆生物制药公司	用於代謝病症和疾病治療的組合物和方法
US9290557B2 (en)	2012-11-28	2016-03-22	Ngm Biopharmaceuticals, Inc.	Compositions comprising variants and fusions of FGF19 polypeptides
ES2915851T3 (es)	2012-12-27	2022-06-27	Ngm Biopharmaceuticals Inc	Péptidos quiméricos de FGF19 para usar en el tratamiento de trastornos de ácidos biliares
US9273107B2 (en)	2012-12-27	2016-03-01	Ngm Biopharmaceuticals, Inc.	Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
CA2927592C (en)	2013-10-28	2020-08-18	Ngm Biopharmaceuticals, Inc.	Fgf-19 variants for treating a fgf-19 dependent cancer or tumor
PE20170256A1 (es)	2014-01-24	2017-04-22	Ngm Biopharmaceuticals Inc	Proteinas de union y sus metodos de uso
WO2015183890A2 (en)	2014-05-28	2015-12-03	Ngm Biopharmaceuticals, Inc.	Methods and compositions for the treatment of metabolic disorders and diseases
AU2015277438B2 (en)	2014-06-16	2020-02-27	Ngm Biopharmaceuticals, Inc.	Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
RU2729161C2 (ru)	2014-10-23	2020-08-04	ЭнДжиЭм БАЙОФАРМАСЬЮТИКАЛЗ, ИНК.	Фармацевтические композиции, содержащие варианты пептидов, и способы их применения
US10434144B2 (en)	2014-11-07	2019-10-08	Ngm Biopharmaceuticals, Inc.	Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
US10800843B2 (en)	2015-07-29	2020-10-13	Ngm Biopharmaceuticals, Inc.	Beta klotho-binding proteins
JP6728352B2 (ja)	2015-11-09	2020-07-22	エヌジーエムバイオファーマシューティカルス，インコーポレーテッド	胆汁酸に関係した障害の治療方法
CA3034399A1 (en)	2016-08-26	2018-03-01	Ngm Biopharmaceuticals, Inc.	Methods of treating fibroblast growth factor 19-mediated cancers and tumors

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Publication number	Priority date	Publication date	Assignee	Title
US5859208A (en) *	1988-07-06	1999-01-12	Fiddes; John C.	Human basic fibroblast growth factor analog
JP2879148B2 (ja) *	1987-07-07	1999-04-05	サイオスインコーポレイテッド	組換え繊維芽細胞成長因子
EP0832215A4 (de) *	1995-06-05	2000-05-17	Human Genome Sciences Inc	Fibroblasten-wachstumsfaktor 11
KR20050009764A (ko) *	1997-11-25	2005-01-25	제넨테크, 인크.	섬유아세포 성장 인자-19

2001
- 2001-01-04 EP EP01901722A patent/EP1246843A1/de not_active Withdrawn
- 2001-01-04 CA CA002396401A patent/CA2396401A1/en not_active Abandoned
- 2001-01-04 JP JP2001550280A patent/JP2003518944A/ja active Pending
- 2001-01-04 AU AU27592/01A patent/AU2759201A/en not_active Abandoned
- 2001-01-04 WO PCT/US2001/000238 patent/WO2001049740A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO2001049740A1 (en)	2001-07-12
AU2759201A (en)	2001-07-16
JP2003518944A (ja)	2003-06-17
EP1246843A1 (de)	2002-10-09

Legal Events

Date	Code	Title	Description
2006-01-03	EEER	Examination request
2009-09-10	FZDE	Dead

Publication	Publication Date	Title
US20080124759A1 (en)	2008-05-29	Novel fgf homolog zfgf12
US20020081663A1 (en)	2002-06-27	Novel FGF homolog ZFGF11
WO2001049849A1 (en)	2001-07-12	Novel fgf homolog zfgf11
CA2396401A1 (en)	2001-07-12	Novel fgf homolog zfgf12
KR100611063B1 (ko)	2006-08-09	섬유아세포 성장인자 상동체
US6518236B1 (en)	2003-02-11	FGF homologs
WO1999055869A1 (en)	1999-11-04	Novel polypeptide growth factors and materials and methods for making them
WO1999032515A2 (en)	1999-07-01	Angiopoietin homolog, dna encoding it, and method of making it
US6395890B1 (en)	2002-05-28	Nucleic acids encoding connective tissue growth factor homologs
US20020031805A1 (en)	2002-03-14	Novel FGF homolog zFGF10
US6531576B1 (en)	2003-03-11	Four-helical bundle protein zsig81
WO2001047957A2 (en)	2001-07-05	Human fgf-10- (kgf-2)-like protein zfgf-10
EP1204681A2 (de)	2002-05-15	Schraubenförmiges zytokin zalpha48
EP1181369B1 (de)	2008-02-13	Vier-helix bündelprotein zsig81
EP1268804A2 (de)	2003-01-02	Helix protein zalpha51
EP1054967A1 (de)	2000-11-29	Bindegewebswachstumsfaktor homologe
US20030153050A1 (en)	2003-08-14	Helical polypeptide zalpha29
WO2001018205A1 (en)	2001-03-15	Secreted polypeptide zalpha30
US20020009775A1 (en)	2002-01-24	Helical protein zalpha51
CA2377580A1 (en)	2001-01-04	Helical polypeptide zalpha29
WO2001029223A2 (en)	2001-04-26	Type i membrane protein ztsl1
CA2374412A1 (en)	2000-12-07	Secreted alpha-helical protein-31