CA2405907A1 - Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 - Google Patents
Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 Download PDFInfo
- Publication number
- CA2405907A1 CA2405907A1 CA002405907A CA2405907A CA2405907A1 CA 2405907 A1 CA2405907 A1 CA 2405907A1 CA 002405907 A CA002405907 A CA 002405907A CA 2405907 A CA2405907 A CA 2405907A CA 2405907 A1 CA2405907 A1 CA 2405907A1
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- Prior art keywords
- sdf
- cells
- cxcr4 agonist
- cxcr4
- amide
- Prior art date
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- Abandoned
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Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Conformément à divers aspects de cette invention, des agonistes de CXCR4, notamment des polypeptides SDF-1 et des homologues de polypeptides SDF-1, peuvent être utilisés pour la réduction du taux de multiplication des cellules hématopoïétiques. Des procédés de cette invention peuvent comprendre l'administration d'une quantité efficace d'un antagoniste de CXCR4 à des cellules choisies dans le groupe comprenant des cellules souches hématopoïétiques et des cellules primordiales hématopoïétiques. Les cellules peuvent être traitées in vitro ou in vivo dans un patient. Une quantité thérapeutiquement efficace dudit agoniste de CXCR4 peut être administrée à un patient dont la condition nécessite un tel traitement. Des patients dont la condition exige de tels traitements peuvent comprendre par exemple, des patients nécessitant une greffe de moelle osseuse ou une greffe de cellules souches du sang périphérique.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002405907A CA2405907A1 (fr) | 2000-04-12 | 2001-04-12 | Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 |
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002305036A CA2305036A1 (fr) | 2000-04-12 | 2000-04-12 | Traitement de cellules hematopoietiques a l'aide d'agonistes du cxcr4 |
| CA2,305,036 | 2000-04-12 | ||
| US23242500P | 2000-09-14 | 2000-09-14 | |
| US60/232,425 | 2000-09-14 | ||
| CA002335109A CA2335109A1 (fr) | 2000-04-12 | 2001-02-23 | Traitement de cellules hematopoietiques avec des agonistes du cxcr4 |
| CA2,335,109 | 2001-02-23 | ||
| CA002405907A CA2405907A1 (fr) | 2000-04-12 | 2001-04-12 | Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 |
| PCT/CA2001/000540 WO2001076615A2 (fr) | 2000-04-12 | 2001-04-12 | Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2405907A1 true CA2405907A1 (fr) | 2001-10-18 |
Family
ID=27427599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002405907A Abandoned CA2405907A1 (fr) | 2000-04-12 | 2001-04-12 | Traitement de cellules hematopoietiques utilisant des agonistes de cxcr4 |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2405907A1 (fr) |
-
2001
- 2001-04-12 CA CA002405907A patent/CA2405907A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |