CA2412089A1 - Vaccin de proteines de prostase contenant des residus thiol derives, et procedes de production dudit antigene - Google Patents

Vaccin de proteines de prostase contenant des residus thiol derives, et procedes de production dudit antigene Download PDF

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Publication number
CA2412089A1
CA2412089A1 CA002412089A CA2412089A CA2412089A1 CA 2412089 A1 CA2412089 A1 CA 2412089A1 CA 002412089 A CA002412089 A CA 002412089A CA 2412089 A CA2412089 A CA 2412089A CA 2412089 A1 CA2412089 A1 CA 2412089A1
Authority
CA
Canada
Prior art keywords
protein
antigen
leu
ser
prostase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002412089A
Other languages
English (en)
Inventor
Teresa Elisa Virginia Cabezon Silva
Philippe Jean Gervais Ghislain Permanne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2412089A1 publication Critical patent/CA2412089A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne des dérivés de prostase chimiquement modifiés, des fragments et des homologues de ces derniers. Ces antigènes peuvent être formulés pour produire des vaccins destinés au traitement de tumeurs prostatiques. L'invention concerne également des procédés de purification de protéines et d'homologues de prostase.
CA002412089A 2000-06-27 2001-06-21 Vaccin de proteines de prostase contenant des residus thiol derives, et procedes de production dudit antigene Abandoned CA2412089A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0015722.2 2000-06-27
GBGB0015722.2A GB0015722D0 (en) 2000-06-27 2000-06-27 Vaccine
PCT/EP2001/007081 WO2002000867A1 (fr) 2000-06-27 2001-06-21 Vaccin de proteines de prostase contenant des residus thiol derives, et procedes de production dudit antigene

Publications (1)

Publication Number Publication Date
CA2412089A1 true CA2412089A1 (fr) 2002-01-03

Family

ID=9894497

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002412089A Abandoned CA2412089A1 (fr) 2000-06-27 2001-06-21 Vaccin de proteines de prostase contenant des residus thiol derives, et procedes de production dudit antigene

Country Status (6)

Country Link
EP (1) EP1297118A1 (fr)
JP (1) JP2004501638A (fr)
AU (1) AU2001270585A1 (fr)
CA (1) CA2412089A1 (fr)
GB (1) GB0015722D0 (fr)
WO (1) WO2002000867A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0509738D0 (en) 2005-05-12 2005-06-22 Cambridge Consultants Processor and interface
GB201513921D0 (en) * 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203035A3 (en) * 1998-07-14 2007-12-28 Corixa Corp Compositions and methods for therapy and diagnosis of prostate cancer
CA2378846A1 (fr) * 1999-07-13 2001-01-18 Smithkline Beecham Biologicals S.A. Vaccin

Also Published As

Publication number Publication date
WO2002000867A1 (fr) 2002-01-03
JP2004501638A (ja) 2004-01-22
AU2001270585A1 (en) 2002-01-08
EP1297118A1 (fr) 2003-04-02
GB0015722D0 (en) 2000-08-16

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Legal Events

Date Code Title Description
FZDE Discontinued