CA2414015A1 - Recepteurs - Google Patents

Recepteurs Download PDF

Info

Publication number
CA2414015A1
CA2414015A1 CA002414015A CA2414015A CA2414015A1 CA 2414015 A1 CA2414015 A1 CA 2414015A1 CA 002414015 A CA002414015 A CA 002414015A CA 2414015 A CA2414015 A CA 2414015A CA 2414015 A1 CA2414015 A1 CA 2414015A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
reptr
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002414015A
Other languages
English (en)
Inventor
Jennifer A. Griffin
Deborah A. Kallick
Catherine M. Tribouley
Henry Yue
Danniel B. Nguyen
Y. Tom Tang
Preeti Lal
Jennifer L. Policky
Yalda Azimzai
Dyung Aina M. Lu
Richard Graul
Monique G. Yao
Neil Burford
April J. A. Hafalia
Mariah R. Baughn
Olga Bandman
Chandra Patterson
Junming Yang
Yuming Xu
Ameena R. Gandhi
Bridget A. Warren
Li Ding
Madhusudan M. Sanjanwala
Brendan M. Duggan
Yan Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2414015A1 publication Critical patent/CA2414015A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des récepteurs humains (REPTR) et des polynucléotides qui identifient et codent les récepteurs REPTR. Elle concerne aussi des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Elle concerne enfin des méthodes de diagnostic, de traitement ou de prévention de troubles associés à l'expression aberrante des récepteurs REPTR.
CA002414015A 2000-06-21 2001-06-21 Recepteurs Abandoned CA2414015A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US21402700P 2000-06-21 2000-06-21
US60/214,027 2000-06-21
US22804500P 2000-08-25 2000-08-25
US60/228,045 2000-08-25
US25510400P 2000-12-12 2000-12-12
US60/255,104 2000-12-12
PCT/US2001/019942 WO2001098354A2 (fr) 2000-06-21 2001-06-21 Recepteurs

Publications (1)

Publication Number Publication Date
CA2414015A1 true CA2414015A1 (fr) 2001-12-27

Family

ID=27395939

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002414015A Abandoned CA2414015A1 (fr) 2000-06-21 2001-06-21 Recepteurs

Country Status (4)

Country Link
JP (1) JP2004516812A (fr)
AU (1) AU2001272974A1 (fr)
CA (1) CA2414015A1 (fr)
WO (1) WO2001098354A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
CA2423677A1 (fr) * 2000-10-04 2002-04-11 Curagen Corporation Nouvelles proteines, acides nucleiques codant ces derniers et anticorps diriges contre ces proteines
AU2001293870A1 (en) * 2000-10-16 2002-04-29 Bayer Aktiengesellschaft Regulation of human netrin binding membrane receptor unc5h-1
AU2002237225A1 (en) * 2000-12-05 2002-06-18 Bayer Aktiengesellschaft Regulation of human patched-like protein
AU2002235748A1 (en) * 2000-12-05 2002-06-18 Bayer Aktiengesellschaft Regulation of human patched-like protein
AU2003269557A1 (en) * 2002-10-18 2004-05-04 Lg Life Sciences Ltd. Gene families associated with cancers
JP4675671B2 (ja) * 2005-05-11 2011-04-27 学校法人北里研究所 核酸増幅反応の新規短時間検出方法
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
EP2511298B1 (fr) 2005-10-31 2019-01-16 Oncomed Pharmaceuticals, Inc. Compositions et procédés pour le traitement du cancer utilisant des recepteurs FZD humains
CL2007002609A1 (es) 2006-09-08 2008-04-18 Genentech Inc Antagonista de wnt que comprende un componente del dominio frizzled y un dominio fc; secuencia de acidos nucleicos que lo codifica; composicion que lo comprende; y su uso para tratar trastornos de proliferacion celular.
TWI506037B (zh) 2008-09-26 2015-11-01 Oncomed Pharm Inc 捲曲結合劑類及彼等之用途
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt拮抗劑及治療和篩選方法
WO2011123785A2 (fr) 2010-04-01 2011-10-06 Oncomed Pharmaceuticals, Inc. Agents de liaison aux récepteurs frizzled et leurs utilisations
EP2911691B1 (fr) 2012-10-23 2018-10-10 OncoMed Pharmaceuticals, Inc. Méthodes de traitement de tumeurs neuro-endocrines à l'aide d'agents liants de parcours wnt
JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Wnt経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939271A (en) * 1997-02-19 1999-08-17 The Regents Of The University Of California Netrin receptor
CA2399776A1 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Acides nucleiques et polypeptides

Also Published As

Publication number Publication date
WO2001098354A3 (fr) 2002-10-17
AU2001272974A1 (en) 2002-01-02
WO2001098354A2 (fr) 2001-12-27
JP2004516812A (ja) 2004-06-10

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Legal Events

Date Code Title Description
FZDE Dead