CA2425574C - Procede et appareil pour generer un liquide de perfusion sterile - Google Patents

Procede et appareil pour generer un liquide de perfusion sterile Download PDF

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Publication number
CA2425574C
CA2425574C CA002425574A CA2425574A CA2425574C CA 2425574 C CA2425574 C CA 2425574C CA 002425574 A CA002425574 A CA 002425574A CA 2425574 A CA2425574 A CA 2425574A CA 2425574 C CA2425574 C CA 2425574C
Authority
CA
Canada
Prior art keywords
fluid
conduit
connector
sterile
sterile infusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002425574A
Other languages
English (en)
Other versions
CA2425574A1 (fr
Inventor
Gregory R. Collins
James Summerton
Edward Spence
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nephros Inc
Original Assignee
Nephros Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nephros Inc filed Critical Nephros Inc
Publication of CA2425574A1 publication Critical patent/CA2425574A1/fr
Application granted granted Critical
Publication of CA2425574C publication Critical patent/CA2425574C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1668—Details of containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1672—Apparatus for preparing dialysates using membrane filters, e.g. for sterilising the dialysate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/22—Controlling or regulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/30—Accessories; Auxiliary operation
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/44—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
    • C02F1/444—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis by ultrafiltration or microfiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Organic Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un appareil et un procédé permettant de générer un liquide de perfusion stérile à partir d'un liquide de perfusion non stérile produit par une machine. Dans un mode de réalisation, le liquide de perfusion stérile est produit par un dispositif générant du liquide stérile, lequel dispositif constituant un dispositif auxiliaire conçu pour fonctionner conjointement à la machine existante. Par exemple, selon un mode de réalisation, le dispositif générant du liquide stérile peut être utilisé conjointement à une machine de dialyse, permettant ainsi de produire du liquide de perfusion stérile.
CA002425574A 2000-10-19 2001-10-19 Procede et appareil pour generer un liquide de perfusion sterile Expired - Fee Related CA2425574C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24166200P 2000-10-19 2000-10-19
US60/241,662 2000-10-19
PCT/US2001/050719 WO2002032476A2 (fr) 2000-10-19 2001-10-19 Procede et appareil pour generer un liquide de perfusion sterile

Publications (2)

Publication Number Publication Date
CA2425574A1 CA2425574A1 (fr) 2002-04-25
CA2425574C true CA2425574C (fr) 2008-05-13

Family

ID=22911654

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002425574A Expired - Fee Related CA2425574C (fr) 2000-10-19 2001-10-19 Procede et appareil pour generer un liquide de perfusion sterile

Country Status (8)

Country Link
US (1) US7108790B2 (fr)
EP (1) EP1343576B1 (fr)
JP (1) JP4094946B2 (fr)
AT (1) ATE354378T1 (fr)
AU (1) AU2002232900A1 (fr)
CA (1) CA2425574C (fr)
DE (1) DE60126817T2 (fr)
WO (1) WO2002032476A2 (fr)

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US6649063B2 (en) 2001-07-12 2003-11-18 Nxstage Medical, Inc. Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit
AU2003237403A1 (en) 2002-06-06 2003-12-22 Nxstage Medical, Inc. Last-chance quality check and/or air/pyrogen filter for infusion systems
EP1523350B1 (fr) 2002-07-19 2011-04-13 Baxter International Inc. Systeme de dialyse peritoneale
FR2845605B1 (fr) * 2002-10-15 2005-01-28 Gambro Lundia Ab Procede et dispositif pour la preparation en ligne de liquide pour un appareil destine au traitement extracorporel du sang
US20080210606A1 (en) * 2004-01-07 2008-09-04 Jeffrey Burbank Filtration System Preparation of Fluids for Medical Applications
ATE434454T1 (de) 2003-01-07 2009-07-15 Nxstage Medical Inc Chargenfiltriersystem zur herstellung einer sterilen ersatzflüssigkeit für nierenbehandlungen
US9700663B2 (en) 2005-01-07 2017-07-11 Nxstage Medical, Inc. Filtration system for preparation of fluids for medical applications
US7135142B2 (en) * 2003-08-01 2006-11-14 Steris Inc. Filter assembly for a reprocessor
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
DE602006017654D1 (de) 2005-01-07 2010-12-02 Nxstage Medical Inc Filterungssystem zur herstellung von flüssigkeiten für medizinische anwendungen
JP5378203B2 (ja) 2006-04-07 2013-12-25 ネクステージ メディカル インコーポレイテッド 医療用の流体を作るろ過システム
US7967022B2 (en) 2007-02-27 2011-06-28 Deka Products Limited Partnership Cassette system integrated apparatus
US8870811B2 (en) * 2006-08-31 2014-10-28 Fresenius Medical Care Holdings, Inc. Peritoneal dialysis systems and related methods
US7736328B2 (en) 2007-07-05 2010-06-15 Baxter International Inc. Dialysis system having supply container autoconnection
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US10265454B2 (en) 2008-07-25 2019-04-23 Baxter International Inc. Dialysis system with flow regulation device
DE102008045422B4 (de) 2008-09-02 2017-10-12 Fresenius Medical Care Deutschland Gmbh Vorrichtung zum Befüllen eines Filters und Verfahren hierzu
JP5736661B2 (ja) * 2010-04-09 2015-06-17 ニプロ株式会社 透析用配管内の汚染防止方法
EP2688602B1 (fr) 2011-03-23 2019-11-06 NxStage Medical, Inc. Systèmes de dialyse péritonéale, dispositif et méthodes
US20130146541A1 (en) 2011-12-13 2013-06-13 Nxstage Medical, Inc. Fluid purification methods, devices, and systems
KR101394505B1 (ko) 2012-09-18 2014-05-13 드림인 영농조합법인 비가열 정제살균주입장치
JP6072288B2 (ja) 2012-12-03 2017-02-01 イー・エム・デイー・ミリポア・コーポレイシヨン 重複滅菌濾過のために使用される方法及び装置
GB201305757D0 (en) * 2013-03-28 2013-05-15 Quanta Fluid Solutions Ltd Disposable Cartridge System for use with Sorbent
KR101578350B1 (ko) 2014-06-13 2015-12-17 드림식품기계공업 주식회사 비가열 정제살균주입장치
ES2987653T3 (es) 2015-06-25 2024-11-15 Gambro Lundia Ab Sistema y método de dispositivo médico que tiene una base de datos distribuida
EP3452140B1 (fr) 2016-05-06 2023-02-22 Gambro Lundia AB Système de dialyse péritonéale ayant une préparation de fluide de dialyse à point d'utilisation utilisant un accumulateur d'eau et un ensemble jetable
DE102016010222A1 (de) * 2016-08-20 2018-02-22 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Bereitstellung von Dialysierflüssigkeit und Dialysevorrichtung
AU2017381172A1 (en) 2016-12-21 2019-06-13 Gambro Lundia Ab Medical device system including information technology infrastructure having secure cluster domain supporting external domain
US11135345B2 (en) 2017-05-10 2021-10-05 Fresenius Medical Care Holdings, Inc. On demand dialysate mixing using concentrates
WO2018237375A1 (fr) 2017-06-24 2018-12-27 Nxstage Medical, Inc. Procédés et systèmes de préparation et/ou de traitement de fluide de dialyse péritonéale
CA3092575A1 (fr) 2018-02-28 2019-09-06 Nxstage Medical, Inc. Dispositifs, procedes et systemes de preparation de fluide et de traitement
IT201800005288A1 (it) * 2018-05-11 2019-11-11 Macchina per emodialisi provvista di un sistema di misura della portata di un liquido e relativo metodo di funzionamento
US11504458B2 (en) 2018-10-17 2022-11-22 Fresenius Medical Care Holdings, Inc. Ultrasonic authentication for dialysis
IT202000025105A1 (it) * 2020-10-22 2022-04-22 Baxter Int Sistema di generazione di fluidi medicali
IT202000025108A1 (it) * 2020-10-22 2022-04-22 Baxter Int Sistema di generazione di fluidi medicali
US20230211260A1 (en) * 2021-12-31 2023-07-06 Pall Corporation Fluid filtration system with single use filter and method of using same for automated filter conditioning

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Also Published As

Publication number Publication date
US20040045881A1 (en) 2004-03-11
WO2002032476A3 (fr) 2002-08-22
CA2425574A1 (fr) 2002-04-25
AU2002232900A1 (en) 2002-04-29
EP1343576B1 (fr) 2007-02-21
WO2002032476A2 (fr) 2002-04-25
US7108790B2 (en) 2006-09-19
DE60126817T2 (de) 2007-12-06
JP2004518462A (ja) 2004-06-24
DE60126817D1 (de) 2007-04-05
JP4094946B2 (ja) 2008-06-04
ATE354378T1 (de) 2007-03-15
EP1343576A2 (fr) 2003-09-17
EP1343576A4 (fr) 2004-08-18

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Effective date: 20141020