CA2436366A1 - Biosynthese de carotenoides - Google Patents

Biosynthese de carotenoides Download PDF

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Publication number
CA2436366A1
CA2436366A1 CA002436366A CA2436366A CA2436366A1 CA 2436366 A1 CA2436366 A1 CA 2436366A1 CA 002436366 A CA002436366 A CA 002436366A CA 2436366 A CA2436366 A CA 2436366A CA 2436366 A1 CA2436366 A1 CA 2436366A1
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CA
Canada
Prior art keywords
nucleic acid
seq
sequence
isolated nucleic
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002436366A
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English (en)
Inventor
Mervyn L. De Souza
Sherry R. Kollmann
Colleen A. May
William A. Schroeder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
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Individual
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Filing date
Publication date
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Publication of CA2436366A1 publication Critical patent/CA2436366A1/fr
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01029—Geranylgeranyl diphosphate synthase (2.5.1.29)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Husbandry (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Feed For Specific Animals (AREA)
  • Farming Of Fish And Shellfish (AREA)

Abstract

L'invention concerne des bactéries membraneuses produisant de l'astaxanthine et d'autres caroténoïdes. Elle concerne aussi des acides nucléaires isolés et des vecteurs d'expression pouvant être utilisés dans la production de caroténoïdes dans des micro-organismes.
CA002436366A 2001-01-26 2002-01-25 Biosynthese de carotenoides Abandoned CA2436366A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26432901P 2001-01-26 2001-01-26
US60/264,329 2001-01-26
US28898401P 2001-05-04 2001-05-04
US60/288,984 2001-05-04
PCT/US2002/002124 WO2002079395A2 (fr) 2001-01-26 2002-01-25 Biosynthese de carotenoides

Publications (1)

Publication Number Publication Date
CA2436366A1 true CA2436366A1 (fr) 2002-10-10

Family

ID=26950419

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002436366A Abandoned CA2436366A1 (fr) 2001-01-26 2002-01-25 Biosynthese de carotenoides

Country Status (6)

Country Link
EP (1) EP1377598A4 (fr)
JP (1) JP2004528839A (fr)
AU (1) AU2002311758A1 (fr)
CA (1) CA2436366A1 (fr)
NO (1) NO20033353L (fr)
WO (1) WO2002079395A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818424B2 (en) 2000-09-01 2004-11-16 E. I. Du Pont De Nemours And Company Production of cyclic terpenoids
US20030148319A1 (en) * 2001-08-15 2003-08-07 Brzostowicz Patricia C. Genes encoding carotenoid compounds
US7063955B2 (en) 2001-11-20 2006-06-20 E. I. Du Pont De Nemours And Company Method for production of asymmetric carotenoids
US20040151761A1 (en) * 2003-02-05 2004-08-05 The Procter & Gamble Company Methods and compositions utilizing astaxanthin
US7070952B2 (en) 2003-05-07 2006-07-04 E. I. Du Pont Nemours And Company Genes encoding carotenoid compounds
US7064196B2 (en) 2003-05-20 2006-06-20 E. I. Du Pont De Nemours And Company Genes encoding carotenoid compounds
US6929928B2 (en) * 2003-06-12 2005-08-16 E. I. Du Pont De Nemours And Company Genes encoding carotenoid compounds
DE102004007624A1 (de) * 2004-02-17 2005-09-15 Sungene Gmbh & Co. Kgaa Neue Ketolasen und Verfahren zur Herstellung von Ketocarotinoiden
DE102004007622A1 (de) * 2004-02-17 2005-08-25 Sungene Gmbh & Co. Kgaa Verfahren zur Herstellung von Ketocarotinoiden in genetisch veränderten, nicht-humanen Organismen
WO2005047486A2 (fr) 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Production biologique de tetradehydrolycopene
ATE458809T1 (de) * 2003-11-18 2010-03-15 Kirin Holdings Kk Neues carotenoidhydroxylasegen, verfahren zur herstellung von hydroxyliertem carotenoid und neues geranylgeranylpyrophosphatsynthasegen
WO2005062867A2 (fr) 2003-12-19 2005-07-14 E.I. Dupont De Nemours And Company Nouvelles cetolases de carotenoide
FR2864968B1 (fr) * 2004-01-09 2007-10-05 Inst Rech Developpement Ird Procede de production de carotenoides et bacteries mises en oeuvre
EP1780281B1 (fr) * 2004-06-04 2013-12-11 Kirin Holdings Kabushiki Kaisha Procédé de production de l'astaxanthine ou d'un produit métabolique de ce composé en utilisant les gènes de la caroténoïde cétolase et de la caroténoïde hydrolase
US7425625B2 (en) 2004-06-08 2008-09-16 E.I. Du Pont De Nemours And Company Carotenoid ketolase genes with improved ketocarotenoid yield
US7091031B2 (en) 2004-08-16 2006-08-15 E. I. Du Pont De Nemours And Company Carotenoid hydroxylase enzymes
US7074604B1 (en) 2004-12-29 2006-07-11 E. I. Du Pont De Nemours And Company Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US7393671B2 (en) 2006-03-30 2008-07-01 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolases
US7422873B2 (en) 2006-03-31 2008-09-09 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolase
WO2008042338A2 (fr) 2006-09-28 2008-04-10 Microbia, Inc. Production de caroténoïdes dans des levures et des champignons oléagineux
US20120171734A1 (en) * 2009-07-01 2012-07-05 The Regents Of The University Of California Extraction of extracellular terpenoids from microalgae colonies
CN112119951A (zh) * 2020-10-30 2020-12-25 西藏自治区农牧科学院水产科学研究所 一种尖裸鲤亲鱼的培育方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429939A (en) * 1989-04-21 1995-07-04 Kirin Beer Kabushiki Kaisha DNA sequences useful for the synthesis of carotenoids
US5684238A (en) * 1990-03-02 1997-11-04 Amoco Corporation Biosynthesis of zeaxanthin and glycosylated zeaxanthin in genetically engineered hosts
AU702584B2 (en) * 1993-12-27 1999-02-25 Kirin Holdings Kabushiki Kaisha DNA strands useful for the synthesis of xanthophylls and the process for producing the xanthophylls
JPH0889241A (ja) * 1994-09-30 1996-04-09 Asahi Chem Ind Co Ltd β−カロチンの生産に有用な遺伝子およびβ−カロチンの製造方法
US5916791A (en) * 1995-11-24 1999-06-29 Hirschberg; Joseph Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a β--C--4--oxygenase activity for biotechnological production of (3S,3S)astaxanthin

Also Published As

Publication number Publication date
AU2002311758A1 (en) 2002-10-15
WO2002079395A2 (fr) 2002-10-10
WO2002079395A3 (fr) 2003-10-23
NO20033353L (no) 2003-09-25
JP2004528839A (ja) 2004-09-24
EP1377598A4 (fr) 2005-08-03
EP1377598A2 (fr) 2004-01-07
NO20033353D0 (no) 2003-07-25
WO2002079395A9 (fr) 2003-06-05

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