CA2437250A1 - Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente - Google Patents

Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente Download PDF

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Publication number
CA2437250A1
CA2437250A1 CA 2437250 CA2437250A CA2437250A1 CA 2437250 A1 CA2437250 A1 CA 2437250A1 CA 2437250 CA2437250 CA 2437250 CA 2437250 A CA2437250 A CA 2437250A CA 2437250 A1 CA2437250 A1 CA 2437250A1
Authority
CA
Canada
Prior art keywords
alginate
cells
islet
islets
des
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2437250
Other languages
English (en)
Inventor
Francois Leblond
Guillaume Jourdan
Jean-Pierre Halle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMS RECH Inc
Original Assignee
IMS RECHERCHE Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMS RECHERCHE Inc filed Critical IMS RECHERCHE Inc
Priority to CA 2437250 priority Critical patent/CA2437250A1/fr
Publication of CA2437250A1 publication Critical patent/CA2437250A1/fr
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622Microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA 2437250 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente Abandoned CA2437250A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2437250 CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2437250 CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Publications (1)

Publication Number Publication Date
CA2437250A1 true CA2437250A1 (fr) 2005-02-14

Family

ID=34140448

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2437250 Abandoned CA2437250A1 (fr) 2003-08-14 2003-08-14 Microencapsulation de cellules vivantes dans des membranes d'alginate-poly-l-lysine-alginate a reticulation covalente

Country Status (1)

Country Link
CA (1) CA2437250A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011011962A1 (fr) * 2009-07-31 2011-02-03 清华大学 Méthode de préparation de précurseurs complexes d’organes tissulaires multicouches
RU2429864C2 (ru) * 2005-10-21 2011-09-27 Ливинг Селл Продактс Пти Лимитед Система инкапсуляции
US8202701B2 (en) 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
US11077289B2 (en) 2013-03-07 2021-08-03 Viacyte, Inc. 3-dimensional large capacity cell encapsulation device assembly
CN113730372A (zh) * 2021-10-15 2021-12-03 中国人民解放军陆军军医大学第二附属医院 一种神经干细胞磷脂膜微囊及其制备方法
CN114767837A (zh) * 2022-05-05 2022-07-22 合肥工业大学 一种口服胰岛素脂质体水凝胶及其应用
CN115737600A (zh) * 2022-11-25 2023-03-07 苏州大学 一种持续产氢生物微球及其制备方法与应用
CN119274722A (zh) * 2024-12-11 2025-01-07 青岛沙木新材料有限公司 单组分无溶剂刷涂型透明防水聚脲配方优化方法

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202701B2 (en) 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
RU2429864C2 (ru) * 2005-10-21 2011-09-27 Ливинг Селл Продактс Пти Лимитед Система инкапсуляции
WO2011011962A1 (fr) * 2009-07-31 2011-02-03 清华大学 Méthode de préparation de précurseurs complexes d’organes tissulaires multicouches
US11077289B2 (en) 2013-03-07 2021-08-03 Viacyte, Inc. 3-dimensional large capacity cell encapsulation device assembly
US12296125B2 (en) 2013-03-07 2025-05-13 Viacyte, Inc. 3-dimensional large capacity cell encapsulation device assembly
CN113730372A (zh) * 2021-10-15 2021-12-03 中国人民解放军陆军军医大学第二附属医院 一种神经干细胞磷脂膜微囊及其制备方法
CN114767837A (zh) * 2022-05-05 2022-07-22 合肥工业大学 一种口服胰岛素脂质体水凝胶及其应用
CN115737600A (zh) * 2022-11-25 2023-03-07 苏州大学 一种持续产氢生物微球及其制备方法与应用
CN115737600B (zh) * 2022-11-25 2024-05-31 苏州大学 一种持续产氢生物微球及其制备方法与应用
CN119274722A (zh) * 2024-12-11 2025-01-07 青岛沙木新材料有限公司 单组分无溶剂刷涂型透明防水聚脲配方优化方法

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