CA2460959A1 - Enzymes - Google Patents
Enzymes Download PDFInfo
- Publication number
- CA2460959A1 CA2460959A1 CA002460959A CA2460959A CA2460959A1 CA 2460959 A1 CA2460959 A1 CA 2460959A1 CA 002460959 A CA002460959 A CA 002460959A CA 2460959 A CA2460959 A CA 2460959A CA 2460959 A1 CA2460959 A1 CA 2460959A1
- Authority
- CA
- Canada
- Prior art keywords
- polynucleotide
- seq
- polypeptide
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- HUHWZXWWOFSFKF-UHFFFAOYSA-N uroporphyrinogen-III Chemical compound C1C(=C(C=2CCC(O)=O)CC(O)=O)NC=2CC(=C(C=2CCC(O)=O)CC(O)=O)NC=2CC(N2)=C(CC(O)=O)C(CCC(=O)O)=C2CC2=C(CCC(O)=O)C(CC(O)=O)=C1N2 HUHWZXWWOFSFKF-UHFFFAOYSA-N 0.000 description 1
- 210000004509 vascular smooth muscle cell Anatomy 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 201000010866 very long chain acyl-CoA dehydrogenase deficiency Diseases 0.000 description 1
- 230000028973 vesicle-mediated transport Effects 0.000 description 1
- 201000010653 vesiculitis Diseases 0.000 description 1
- 229960000744 vinpocetine Drugs 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229960005080 warfarin Drugs 0.000 description 1
- PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 description 1
- 229940075420 xanthine Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
Abstract
Sous diverses variantes, l'invention concerne des enzymes humaines (ENZM) et des polynucléotides qui identifient et codent ces enzymes ENZM. Différentes variantes concernent en outre des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. D'autres variantes concernent des procédés pour le diagnostic, le traitement ou la prévention de troubles associés à l'expression aberrante des enzymes ENZM.
Applications Claiming Priority (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32638801P | 2001-09-28 | 2001-09-28 | |
| US60/326,388 | 2001-09-28 | ||
| US32897901P | 2001-10-12 | 2001-10-12 | |
| US60/328,979 | 2001-10-12 | ||
| US34603401P | 2001-10-19 | 2001-10-19 | |
| US60/346,034 | 2001-10-19 | ||
| US34828401P | 2001-10-26 | 2001-10-26 | |
| US60/348,284 | 2001-10-26 | ||
| US33804801P | 2001-11-08 | 2001-11-08 | |
| US60/338,048 | 2001-11-08 | ||
| US33234001P | 2001-11-16 | 2001-11-16 | |
| US60/332,340 | 2001-11-16 | ||
| US34035701P | 2001-12-14 | 2001-12-14 | |
| US60/340,357 | 2001-12-14 | ||
| US36872202P | 2002-03-29 | 2002-03-29 | |
| US36879902P | 2002-03-29 | 2002-03-29 | |
| US60/368,799 | 2002-03-29 | ||
| US60/368,722 | 2002-03-29 | ||
| US38155802P | 2002-05-17 | 2002-05-17 | |
| US60/381,588 | 2002-05-17 | ||
| US38711902P | 2002-06-07 | 2002-06-07 | |
| US60/387,119 | 2002-06-07 | ||
| US39066202P | 2002-06-21 | 2002-06-21 | |
| US60/390,662 | 2002-06-21 | ||
| PCT/US2002/031096 WO2003042357A2 (fr) | 2001-09-28 | 2002-09-26 | Enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2460959A1 true CA2460959A1 (fr) | 2003-05-22 |
Family
ID=27583841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002460959A Abandoned CA2460959A1 (fr) | 2001-09-28 | 2002-09-26 | Enzymes |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1434860A2 (fr) |
| JP (1) | JP2005525788A (fr) |
| AU (1) | AU2002347778A1 (fr) |
| CA (1) | CA2460959A1 (fr) |
| WO (1) | WO2003042357A2 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005076012A2 (fr) * | 2004-01-30 | 2005-08-18 | Five Prime Therapeutics, Inc. | Nouveaux variants d'epissure et methodes d'utilisation associees |
| EP1642905B1 (fr) * | 2004-10-02 | 2009-01-21 | Immatics Biotechnologies GmbH | Epitopes T-auxiliaires d'antigènes tumoraux humains et leur utilisation en méthodes immunothérapeutiques |
| CN101160524A (zh) * | 2005-02-24 | 2008-04-09 | 西米尼斯公司 | 用于生物样品分类的组合物和方法 |
| US20100216703A1 (en) * | 2006-08-14 | 2010-08-26 | The Regents Of The University Of California | Inhibitors of PDE4 and Methods of Use |
| NZ607996A (en) | 2010-09-22 | 2014-07-25 | Alios Biopharma Inc | Substituted nucleotide analogs |
| CA2860234A1 (fr) | 2011-12-22 | 2013-06-27 | Alios Biopharma, Inc. | Analogues de nucleotide phosphorothioate substitue |
| HK1206362A1 (zh) | 2012-03-21 | 2016-01-08 | Alios Biopharma, Inc. | 硫代氨基磷酸酯核苷酸前藥的固體形式 |
| WO2013142157A1 (fr) | 2012-03-22 | 2013-09-26 | Alios Biopharma, Inc. | Combinaisons pharmaceutiques comprenant un analogue thionucléotidique |
| US10077432B2 (en) * | 2014-03-21 | 2018-09-18 | Ikeda Food Research Co., Ltd. | Flavin-conjugated glucose dehydrogenase |
| EP3526344B1 (fr) * | 2016-10-13 | 2020-09-30 | Biomérieux | Identification et caractérisation antibiotique des pathogènes d'un échantillon métagénomique |
| CN110749687B (zh) * | 2019-04-04 | 2021-05-28 | 中山大学 | 一种日本血吸虫病早期诊断尿液生物标志物及筛选方法和应用 |
| CN119082052B (zh) * | 2023-01-18 | 2025-07-22 | 安徽华恒生物科技股份有限公司 | 一种转运蛋白变体及其在r-泛解酸制备中的应用 |
-
2002
- 2002-09-26 CA CA002460959A patent/CA2460959A1/fr not_active Abandoned
- 2002-09-26 AU AU2002347778A patent/AU2002347778A1/en not_active Abandoned
- 2002-09-26 JP JP2003544177A patent/JP2005525788A/ja active Pending
- 2002-09-26 EP EP02783990A patent/EP1434860A2/fr not_active Withdrawn
- 2002-09-26 WO PCT/US2002/031096 patent/WO2003042357A2/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005525788A (ja) | 2005-09-02 |
| AU2002347778A1 (en) | 2003-05-26 |
| EP1434860A2 (fr) | 2004-07-07 |
| WO2003042357A2 (fr) | 2003-05-22 |
| WO2003042357A3 (fr) | 2003-11-20 |
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