CA2463090C - Vaccin antirabique recombine, preparation et utilisation de ce vaccin - Google Patents
Vaccin antirabique recombine, preparation et utilisation de ce vaccin Download PDFInfo
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- CA2463090C CA2463090C CA2463090A CA2463090A CA2463090C CA 2463090 C CA2463090 C CA 2463090C CA 2463090 A CA2463090 A CA 2463090A CA 2463090 A CA2463090 A CA 2463090A CA 2463090 C CA2463090 C CA 2463090C
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- rabies
- vaccine
- spbnga
- protein
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
L'invention concerne des vaccins antirabiques à virus vivants comprenant un génome recombiné de virus de la rage qui provoque une surexpression de la protéine G du virus de la rage. Ces vaccins augmentent l'activité apoptotique dans les cellules infectées et entraînent l'apparition d'une immunité antirabique chez le sujet.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32835001P | 2001-10-10 | 2001-10-10 | |
| US60/328,350 | 2001-10-10 | ||
| PCT/US2002/032475 WO2003030933A1 (fr) | 2001-10-10 | 2002-10-10 | Vaccin antirabique recombine, preparation et utilisation de ce vaccin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2463090A1 CA2463090A1 (fr) | 2003-04-17 |
| CA2463090C true CA2463090C (fr) | 2012-06-12 |
Family
ID=23280622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2463090A Expired - Lifetime CA2463090C (fr) | 2001-10-10 | 2002-10-10 | Vaccin antirabique recombine, preparation et utilisation de ce vaccin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7223584B2 (fr) |
| EP (1) | EP1439856B1 (fr) |
| AT (1) | ATE427119T1 (fr) |
| CA (1) | CA2463090C (fr) |
| DE (1) | DE60231821D1 (fr) |
| WO (1) | WO2003030933A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003087339A2 (fr) * | 2002-04-11 | 2003-10-23 | Medimmune Vaccines, Inc. | Lyophilisation par pulverisation de compositions a administration pulmonaire |
| EP1768697B1 (fr) | 2004-07-12 | 2010-06-02 | Thomas Jefferson University | Compositions contre des virus rabiques recombinants |
| CA2943039C (fr) | 2005-10-14 | 2018-11-06 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Compositions et procedes contre des virus rabiques |
| CA2736604C (fr) * | 2008-09-17 | 2017-01-03 | Charles Rupprecht | Compositions immunocontraceptives recombinantes a base du virus de la rage et methodes d'utilisation |
| US8282939B2 (en) * | 2009-09-11 | 2012-10-09 | Thomas Jefferson University | Attenuated live triple G protein recombinant rabies virus vaccine for pre- and post-exposure prophylaxis of rabies |
| CN101768575B (zh) * | 2010-01-15 | 2013-06-12 | 中国农业科学院哈尔滨兽医研究所 | 双表达g基因的重组狂犬病病毒的构建及其生物学特性分析 |
| WO2011163446A2 (fr) * | 2010-06-24 | 2011-12-29 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Vaccins anti-lyssavirus contre la rage |
| CN103323588A (zh) * | 2012-03-19 | 2013-09-25 | 郑州中道生物技术有限公司 | 一种犬狂犬病毒抗体的检测方法及检测试剂盒 |
| WO2014055289A1 (fr) * | 2012-10-01 | 2014-04-10 | Thomas Jefferson University | Immunisation par un vecteur viral de la rage exprimant un antigène protéique étranger |
| CN104599668B (zh) * | 2014-12-18 | 2018-02-02 | 清华大学 | 基于稀疏矩阵快速语音识别方法和装置 |
| CN117700522B (zh) * | 2023-12-14 | 2026-07-21 | 吉林大学 | 宿主因子Snapin在狂犬病病毒新型疫苗和救治药物研制中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2693655B1 (fr) * | 1992-07-20 | 1994-10-14 | Virbac | Vaccin antirabique avirulent. |
| US6295531B1 (en) * | 1998-11-09 | 2001-09-25 | Unisys Corporation | Cool ICE data wizard |
| WO2001070932A2 (fr) | 2000-03-23 | 2001-09-27 | Thomas Jefferson University | Vaccin recombine contre la rage genetiquement modifie pour l'immunisation de chiens errants et de la faune |
| US6708173B1 (en) * | 2000-10-18 | 2004-03-16 | Unisys Corporation | Method and apparatus for multiple application trace streams |
| US6836886B2 (en) * | 2001-03-19 | 2004-12-28 | Autodesk, Inc. | Method and apparatus for delivering electronic information |
-
2002
- 2002-10-10 CA CA2463090A patent/CA2463090C/fr not_active Expired - Lifetime
- 2002-10-10 AT AT02801021T patent/ATE427119T1/de not_active IP Right Cessation
- 2002-10-10 EP EP02801021A patent/EP1439856B1/fr not_active Expired - Lifetime
- 2002-10-10 WO PCT/US2002/032475 patent/WO2003030933A1/fr not_active Ceased
- 2002-10-10 DE DE60231821T patent/DE60231821D1/de not_active Expired - Lifetime
- 2002-10-10 US US10/268,197 patent/US7223584B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE427119T1 (de) | 2009-04-15 |
| WO2003030933A1 (fr) | 2003-04-17 |
| US7223584B2 (en) | 2007-05-29 |
| US20030113346A1 (en) | 2003-06-19 |
| EP1439856A4 (fr) | 2005-01-19 |
| DE60231821D1 (de) | 2009-05-14 |
| EP1439856B1 (fr) | 2009-04-01 |
| CA2463090A1 (fr) | 2003-04-17 |
| EP1439856A1 (fr) | 2004-07-28 |
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| EEER | Examination request | ||
| MKEX | Expiry |
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