CA2465274A1 - Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample - Google Patents
Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample Download PDFInfo
- Publication number
- CA2465274A1 CA2465274A1 CA002465274A CA2465274A CA2465274A1 CA 2465274 A1 CA2465274 A1 CA 2465274A1 CA 002465274 A CA002465274 A CA 002465274A CA 2465274 A CA2465274 A CA 2465274A CA 2465274 A1 CA2465274 A1 CA 2465274A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- rna
- cytoplasmic
- combinations
- accomplished
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Environmental Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dentistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33066901P | 2001-10-26 | 2001-10-26 | |
| US60/330,669 | 2001-10-26 | ||
| US36994502P | 2002-04-04 | 2002-04-04 | |
| US60/369,945 | 2002-04-04 | ||
| PCT/US2002/034397 WO2003035894A2 (en) | 2001-10-26 | 2002-10-28 | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2465274A1 true CA2465274A1 (en) | 2003-05-01 |
Family
ID=26987390
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002465274A Abandoned CA2465274A1 (en) | 2001-10-26 | 2002-10-28 | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
| CA002465288A Abandoned CA2465288A1 (en) | 2001-10-26 | 2002-10-28 | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002465288A Abandoned CA2465288A1 (en) | 2001-10-26 | 2002-10-28 | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1438398A2 (de) |
| JP (1) | JP2005507997A (de) |
| KR (1) | KR20040047971A (de) |
| CN (1) | CN1610752A (de) |
| AU (1) | AU2002360305A1 (de) |
| BR (1) | BR0213520A (de) |
| CA (2) | CA2465274A1 (de) |
| IL (1) | IL161357A0 (de) |
| WO (2) | WO2003035894A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US7318902B2 (en) | 2002-02-04 | 2008-01-15 | Colorado School Of Mines | Laminar flow-based separations of colloidal and cellular particles |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| CA2542656A1 (en) * | 2003-10-16 | 2005-05-06 | Genomic Health, Inc. | Qrt-pcr assay system for gene expression profiling |
| US7332597B2 (en) | 2004-06-28 | 2008-02-19 | University Of Kentucky Research Foundation | Primers and probe to identify mycobacterium tuberculosis complex |
| ITBO20040420A1 (it) | 2004-07-07 | 2004-10-07 | Type S R L | Macchina per taglio e formatura di piattine metalliche |
| DE102005013261A1 (de) * | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| DE102005029808A1 (de) * | 2005-06-27 | 2007-01-04 | Siemens Ag | Trägermaterial, Verfahren zu seiner Herstellung und Verwendung |
| ITBO20050481A1 (it) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | Metodo ed apparato per la manipolazione e/o l'individuazione di particelle |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| KR101446626B1 (ko) | 2005-09-02 | 2014-10-06 | 도레이 카부시키가이샤 | 신장암 진단, 신장암 환자 예후 예측을 위한 조성물 및 방법 |
| US20070059683A1 (en) * | 2005-09-15 | 2007-03-15 | Tom Barber | Veterinary diagnostic system |
| ES2886923T3 (es) | 2005-09-20 | 2021-12-21 | Menarini Silicon Biosystems Spa | Métodos y composición para generar sondas de ADN de secuencia única, marcaje de sondas de ADN y el uso de estas sondas |
| US9134237B2 (en) | 2005-09-20 | 2015-09-15 | Janssen Diagnotics, LLC | High sensitivity multiparameter method for rare event analysis in a biological sample |
| ITBO20050646A1 (it) | 2005-10-26 | 2007-04-27 | Silicon Biosystem S R L | Metodo ed apparato per la caratterizzazione ed il conteggio di particelle |
| US9878326B2 (en) | 2007-09-26 | 2018-01-30 | Colorado School Of Mines | Fiber-focused diode-bar optical trapping for microfluidic manipulation |
| US8119976B2 (en) | 2007-07-03 | 2012-02-21 | Colorado School Of Mines | Optical-based cell deformability |
| US9885644B2 (en) | 2006-01-10 | 2018-02-06 | Colorado School Of Mines | Dynamic viscoelasticity as a rapid single-cell biomarker |
| US9487812B2 (en) | 2012-02-17 | 2016-11-08 | Colorado School Of Mines | Optical alignment deformation spectroscopy |
| ITTO20060226A1 (it) | 2006-03-27 | 2007-09-28 | Silicon Biosystem S P A | Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche |
| EP2008102A4 (de) * | 2006-04-18 | 2009-07-08 | Wellstat Biologics Corp | Detektion von proteinen aus zirkulierenden neoplastischen zellen |
| WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| EP2589668A1 (de) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| JP4926812B2 (ja) * | 2007-02-01 | 2012-05-09 | シスメックス株式会社 | 血球分析装置および体液分析方法 |
| US10722250B2 (en) | 2007-09-04 | 2020-07-28 | Colorado School Of Mines | Magnetic-field driven colloidal microbots, methods for forming and using the same |
| ITTO20070771A1 (it) | 2007-10-29 | 2009-04-30 | Silicon Biosystems Spa | Metodo e apparato per la identificazione e manipolazione di particelle |
| HUE031848T2 (en) | 2008-09-20 | 2017-08-28 | Univ Leland Stanford Junior | Non-invasive diagnosis of fetal aneuploidy by sequencing |
| IT1391619B1 (it) | 2008-11-04 | 2012-01-11 | Silicon Biosystems Spa | Metodo per l'individuazione, selezione e analisi di cellule tumorali |
| US10895575B2 (en) | 2008-11-04 | 2021-01-19 | Menarini Silicon Biosystems S.P.A. | Method for identification, selection and analysis of tumour cells |
| CA2782123C (en) | 2009-03-17 | 2017-05-02 | Silicon Biosystems S.P.A. | Microfluidic device for isolation of cells |
| JP5729904B2 (ja) | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | 細胞から蛋白質、dna、rnaを調製する方法 |
| WO2011034115A1 (ja) * | 2009-09-17 | 2011-03-24 | Jsr株式会社 | アビジンとビオチン誘導体の解離方法及び解離剤 |
| BR112012016451A2 (pt) * | 2010-01-04 | 2020-09-08 | Giagen Gaithersburg, INC. | métodos, composições, e kits para recuperação de ácidos nucleicos ou proteínas de amostras de tecido fixadas |
| JP5871933B2 (ja) | 2010-09-10 | 2016-03-01 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | Dna内のrna相互作用領域の検出 |
| CN102565404B (zh) * | 2010-12-24 | 2014-04-16 | 牛刚 | 一种检测血液中游离大肠癌细胞标志物的试剂盒 |
| CN102156164B (zh) * | 2011-01-13 | 2012-12-12 | 北京肿瘤医院 | 核仁磷酸蛋白可变剪接体的质谱鉴定方法和胃癌诊断试剂盒 |
| CN102109525B (zh) * | 2011-01-26 | 2013-10-16 | 牛刚 | 一种检测血液中游离乳腺癌细胞标志物的试剂盒 |
| EP2675913B1 (de) | 2011-02-15 | 2016-12-14 | Bio-Rad Laboratories, Inc. | Erkennung von methylierung in einer subpopulation von genomischer dna |
| US20120252038A1 (en) * | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| EP2739752B1 (de) * | 2011-08-03 | 2017-07-19 | Bio-Rad Laboratories, Inc. | Filterung von kleinen nukleinsäuren anhand von permeabilisierten zellen |
| ITTO20110990A1 (it) | 2011-10-28 | 2013-04-29 | Silicon Biosystems Spa | Metodo ed apparato per l'analisi ottica di particelle a basse temperature |
| ITBO20110766A1 (it) | 2011-12-28 | 2013-06-29 | Silicon Biosystems Spa | Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico |
| WO2014067528A1 (en) * | 2012-10-29 | 2014-05-08 | Arcedi Biotech Aps | Improved enrichment and detection of rare blood cells |
| US9857361B2 (en) | 2013-03-15 | 2018-01-02 | Iris International, Inc. | Flowcell, sheath fluid, and autofocus systems and methods for particle analysis in urine samples |
| ES2658692T3 (es) * | 2013-03-15 | 2018-03-12 | Iris International, Inc. | Método y composición para teñir y procesar una muestra de orina |
| EP3670664B1 (de) * | 2014-02-28 | 2022-09-07 | Gen-Probe Incorporated | Verfahren zur isolierung von nukleinsäure aus proben in flüssigkeitsbasierten zytologischen konservierungsmitteln mit formaldehyd |
| US9771571B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| US9771572B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| JP2014158468A (ja) * | 2014-03-05 | 2014-09-04 | Clinical Genomics Pty Ltd | 検出方法 |
| SG10202104816QA (en) * | 2015-02-10 | 2021-06-29 | Illumina Inc | Methods and compositions for analyzing cellular components |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| US10282588B2 (en) * | 2016-06-09 | 2019-05-07 | Siemens Healthcare Gmbh | Image-based tumor phenotyping with machine learning from synthetic data |
| CN115119829B (zh) | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| CN110456034B (zh) * | 2018-05-07 | 2022-07-22 | 上海市第十人民医院 | 一种循环肿瘤细胞的检测方法 |
| CN109402240B (zh) * | 2019-01-08 | 2020-08-25 | 圣湘生物科技股份有限公司 | 核酸释放剂、核酸pcr扩增方法和pcr扩增试剂盒 |
| KR102707636B1 (ko) * | 2021-11-05 | 2024-09-20 | 고려대학교 세종산학협력단 | 머신러닝 기반의 렌즈프리 그림자 이미징 기술을 이용한 백혈병 진단 방법 및 장치 |
| WO2023080601A1 (ko) * | 2021-11-05 | 2023-05-11 | 고려대학교 세종산학협력단 | 머신러닝 기반의 렌즈프리 그림자 이미징 기술을 이용한 질병 진단 방법 및 장치 |
| JP7757800B2 (ja) * | 2022-01-14 | 2025-10-22 | 株式会社島津製作所 | 電気泳動システム、電気泳動装置、電気泳動解析方法、および、電気泳動解析プログラム |
| CN116042772B (zh) * | 2023-02-10 | 2025-07-29 | 上海立闻生物科技有限公司 | 针对少量来自于新鲜样本的肿瘤细胞全转录组测序的方法和试剂盒 |
| WO2025256538A1 (zh) * | 2024-06-12 | 2025-12-18 | 北京沙砾生物医药股份有限公司 | 一种细胞产品中检测肿瘤残留的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929556A (en) * | 1986-02-06 | 1990-05-29 | The Dow Chemical Company | Enzyme immobilization with polysulfonium salts |
| US5346994A (en) * | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| WO1998004689A1 (en) * | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
| ATE471150T1 (de) * | 1996-03-26 | 2010-07-15 | Kopreski Michael S | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US6156564A (en) * | 1996-06-07 | 2000-12-05 | The United States Of America As Represented By The Department Of Health And Human Services | Cellular apoptosis susceptibility protein (CSP) and antisense CSP |
| WO1999041613A1 (en) * | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| US6156515A (en) * | 1999-02-09 | 2000-12-05 | Urocor, Inc. | Prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
| US6358697B2 (en) * | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
-
2002
- 2002-10-28 IL IL16135702A patent/IL161357A0/xx unknown
- 2002-10-28 WO PCT/US2002/034397 patent/WO2003035894A2/en not_active Ceased
- 2002-10-28 JP JP2003538395A patent/JP2005507997A/ja not_active Ceased
- 2002-10-28 CA CA002465274A patent/CA2465274A1/en not_active Abandoned
- 2002-10-28 BR BRPI0213520-5A patent/BR0213520A/pt unknown
- 2002-10-28 CN CNA028261313A patent/CN1610752A/zh active Pending
- 2002-10-28 CA CA002465288A patent/CA2465288A1/en not_active Abandoned
- 2002-10-28 EP EP02795554A patent/EP1438398A2/de not_active Withdrawn
- 2002-10-28 AU AU2002360305A patent/AU2002360305A1/en not_active Abandoned
- 2002-10-28 KR KR10-2004-7006181A patent/KR20040047971A/ko not_active Withdrawn
- 2002-10-28 EP EP02795565A patent/EP1438419A2/de not_active Withdrawn
- 2002-10-28 WO PCT/US2002/034570 patent/WO2003035895A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002360305A1 (en) | 2003-05-06 |
| WO2003035895A3 (en) | 2004-01-08 |
| WO2003035895A2 (en) | 2003-05-01 |
| BR0213520A (pt) | 2006-05-23 |
| KR20040047971A (ko) | 2004-06-05 |
| EP1438398A2 (de) | 2004-07-21 |
| WO2003035894A2 (en) | 2003-05-01 |
| CA2465288A1 (en) | 2003-05-01 |
| CN1610752A (zh) | 2005-04-27 |
| IL161357A0 (en) | 2004-09-27 |
| WO2003035894A3 (en) | 2003-12-04 |
| EP1438419A2 (de) | 2004-07-21 |
| JP2005507997A (ja) | 2005-03-24 |
| WO2003035894A8 (en) | 2004-06-03 |
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